Lewis Y

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For Research Use Only. Not For Clinical Use.


Background

Lewis Y is a carbohydrate antigen that is expressed on the surface of some cancer cells. It is a type of glycan, which is a complex carbohydrate structure. Lewis Y is considered a tumor-associated carbohydrate antigen (TACA) and has been studied as a potential target for cancer immunotherapy and diagnostics.
The Lewis antigen system is a human blood group system based upon genes on chromosome 19 p13.3 (FUT3 or Lewis gene) and 19q13.3, (FUT2 or secretor gene).
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