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Lewis Y

Anti-Lewis Y Products
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, FuncS, IHC, Inhib
- Anti-Human Lewis Y Recombinant Antibody (MB 311) (TAB-488CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Application: Cyt
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Lewis Y Recombinant Antibody (MB311) (TAB-0015CL)
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- Type: Humanized Antibody
- Application: FC, FuncS
- Anti-Lewis Y Recombinant Antibody (Hu3s193) (TAB-0016CL)
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- Type: Humanized Antibody
- Application: RIA, IHC
- Human Anti-Lewis Y Antibody (clone hu3S193), mRNA (PABX-003-mRNA)
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- Species Reactivity: Human
- Mouse Anti-Lewis Y Antibody, mRNA (PABX-131-mRNA) (PABX-131-mRNA)
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- Human Anti-Lewis Y Recombinant Antibody (clone BR96) (FAMAB-1327CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: IHC, Cyt
- Mouse Anti-Lewis Y Antibody (clone MSL5), mRNA (FAMAB-0207CQ-mRNA)
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- Human Anti-Lewis Y Antibody, mRNA (Gly-044LC-mRNA)
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- Species Reactivity: Human
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
- Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5) (FAMAB-0207CQ)
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- Derivation: Mouse
- Type: Mouse IgG
- Application: ELISA, FC, IHC
- Recombinant Human Anti-LewisY Antibody scFv Fragment (hu3S193) (PABX-003-S (P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, IF, FuncS
- Recombinant Human Anti-LewisY Antibody Fab Fragment (hu3S193) (PABX-003-F (E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, IF, FuncS
- Human Anti-Lewis Y Recombinant Antibody; Fab Fragment (TAB-0019CL-F(E)) (TAB-0019CL-F(E))
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- Type: Humanized Fab
- Application: FuncS
- Anti-Lewis Y Recombinant Antibody Fab Fragment (hABL364) (TAB-0017CL-F(E))
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- Type: Humanized Antibody
- Application: ELISA
- Anti-Lewis Y Recombinant Antibody scFv Fragment (hABL364) (TAB-0017CL-S(P))
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- Type: Humanized Antibody
- Application: ELISA
- Anti-Lewis Y Recombinant Antibody Fab Fragment (MB311) (TAB-0015CL-F(E))
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- Type: Humanized Antibody
- Application: FC
- Anti-Lewis Y Recombinant Antibody Fab Fragment (Hu3s193) (TAB-0016CL-F(E))
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- Type: Humanized Antibody
- Application: ELISA, BI
- Anti-Lewis Y Recombinant Antibody (hABL364) (TAB-0017CL)
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- Type: Humanized Antibody
- Application: CDC, ADCC, ELISA
- Human Anti-Lewis Y Recombinant Antibody; scFv Fragment (TAB-0019CL-S(P)) (TAB-0019CL-S(P))
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- Type: Humanized scFv
- Application: FuncS
- Human Anti-Lewis Y Recombinant Antibody (TAB-0019CL) (TAB-0019CL)
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- Type: Humanized IgG
- Application: FC, FuncS
- Anti-Lewis Y Recombinant Antibody scFv Fragment (MB311) (TAB-0015CL-S(P))
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- Type: Humanized Antibody
- Application: FC
- Anti-Lewis Y Recombinant Antibody scFv Fragment (Hu3s193) (TAB-0016CL-S(P))
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- Type: Humanized Antibody
- Application: ELISA, BI
- Recombinant Anti-LeY Antibody (MOB-620)
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- Derivation: Mouse
- Type: IgG
- Application: WB, IF, FuncS
- Recombinant Human Anti-LeY Antibody (MHH-620)
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- Derivation: Human
- Type: IgG
- Application: ELISA, IP, FuncS
- Human Anti-LeY Recombinant Antibody (clone H18A) (FAMAB-1325CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, IHC
- Human Anti-LeY Antibody (clone H18A), mRNA (FAMAB-1325CQ-mRNA)
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- Species Reactivity: Human
- Recombinant Human Anti-LeY Antibody Fab Fragment (MHH-620-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, IP, FuncS
- Recombinant Human Anti-LeY Antibody scFv Fragment (MHH-620-S(P))
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- Derivation: Human
- Type: scFv
- Application: WB, ELISA, IHC, FuncS
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- Target: Ley
- Species Reactivity: Human
- Cytokine 1: TNFα
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: TNFα-scFv
- Recombinant Anti-LeY Antibody Fab Fragment (MOB-620-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: WB, Neut, FuncS
- Recombinant Anti-LeY Antibody scFv Fragment (MOB-620-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: WB, IF, FuncS
- Anti-Human Lewis Y Recombinant Antibody (3S193) (TAB-0650CL)
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- Application: Cyt, ELISA
- Anti-Human Lewis Y Recombinant Antibody scFv Fragment (3S193) (TAB-0650CL-S(P))
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- Application: ELISA
- Anti-Lewis Y Recombinant Antibody (BR55-2) (TAB-0018CL)
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- Application: Activ, Inhib
- Anti-Lewis Y Recombinant Antibody scFv Fragment (BR55-2) (TAB-0018CL-S(P))
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- Application: FuncS, Inhib
- Anti-Lewis Y Recombinant Antibody Fab Fragment (BR55-2) (TAB-0018CL-F(E))
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- Application: FuncS, Inhib
- Anti-Human Lewis Y Recombinant Antibody Fab Fragment (3S193) (TAB-0650CL-F(E))
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- Application: ELISA
- Recombinant Mouse Anti-LewisY Antibody Fab Fragment (MBR96) (PABX-131-F (E))
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- Derivation: Mouse
- Type: Fab
- Application: WB, Neut, FuncS
- Recombinant Mouse Anti-LewisY Antibody scFv Fragment (MBR96) (PABX-131-S (P))
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- Derivation: Mouse
- Type: scFv
- Application: WB, Neut, FuncS
- Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5); Fab Fragment (FAMAB-0207CQ-F(E))
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- Derivation: Mouse
- Type: Mouse Fab
- Application: FC, IHC
- Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5); scFv Fragment (FAMAB-0207CQ-S(P))
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- Derivation: Mouse
- Type: Mouse scFv
- Application: FC, IHC
- Recombinant Anti-Human Lewis Y VHH Single Domain Antibody (NAB-1634-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IP, ChiP, Neut, ELISA
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- Derivation: Mouse
- Type: IgG
- Application: WB, Neut, FuncS
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- Species Reactivity: Human
- Type: Antibody hexamer
- Application: CDC, ADCC, ELISA
- Human Anti-Lewis Y (clone MB311) scFv-Fc Chimera (VS-0325-FY131)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: ADCC
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Asn297
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Fc region
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For Research Use Only. Not For Clinical Use.
Background
Lewis Y (Le(y)) is a specific blood group antigen, considered a type of sugar molecule, that is expressed on the surface of various cells, particularly epithelial cells, and is often found in high quantities on certain cancers, making it a potential target for cancer treatment due to its unique expression pattern on tumor cells compared to normal tissues; it is part of the Lewis blood group system, which also includes other Lewis antigens like Lewis A and Lewis B.
The Lewis antigen system is a human blood group system based upon genes on chromosome 19 p13.3 (FUT3 or Lewis gene) and 19q13.3, (FUT2 or secretor gene).