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    APC-A*02:01/Human DKK1 (YLGAAGATYV) MHC Tetramer

    CAT#: MHC-CN0357

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, CACO-2, fHDF/TERT166)
    ❯

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • DKK1
    • Antigen Species
    • Human
    • Peptide
    • YLGAAGATYV
    • Conjugate
    • APC
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
    • Alternative Names
    • DKK1; dickkopf WNT signaling pathway inhibitor 1; SK; DKK-1; dickkopf-related protein 1; hDkk-1; dickkopf-1 like; dickkopf 1 homolog
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    Related Signaling Pathways

    Canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway
    Non-Canonical Wnt Signaling Pathway Non-Canonical Wnt Signaling Pathway

    Downloadable Resources

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    Datasheet

    Datasheet - MHC-CN0357.pdf

    MSDS

    MSDS - MHC-CN0357.pdf

    COA

    Certificate of Analysis Lookup

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