Afuco™ Anti-C5 ADCC Recombinant Antibody (Eculizumab), ADCC Enhanced (CAT#: AFC-TAB-008)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human C5. Eculizumab also is the first agent approved for the treatment of atypical hemolytic uremic syndrome (aHUS), an ultra-rare genetic disease that causes abnormal blood clots to form in small blood vessels throughout the body, leading to kidney failure, damage to other vital organs and premature death.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000106804-C5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000106804-C5
Specifications
- Immunogen
- Human C5 protein emulsified with complete Fraud`s adjuvant
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Eculizumab
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Trade name
- Soliris
- Generic Name
- Eculizumab
- Related Disease
- Neuromyelitis optica (NMO)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Eculizumab; soliris; 219685-50-4; h5G1.1; DB01257 C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Gene ID
- 727
- UniProt ID
- P01031
Related Resources
Please refer to Eculizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Eculizumab.
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Eculizumab"
Anti-Human C5 Recombinant Antibody (Eculizumab)Recombinant monoclonal antibody to Human C5. Eculizumab also is the first agent approved for the treatment of atypical hemolytic uremic syndrome (aHUS), an ultra-rare genetic disease that causes abnormal blood clots to form in small blood vessels throughout the body, leading to kidney failure, damage to other vital organs and premature death.
See other products for "Clone Eculizumab"
See other products for "C5"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody
Humanized Antibody
Neutralizing Antibody
Blocking Antibody
Rabbit Monoclonal Antibody
Human Antibody
Recombinant Antibody
Fab Fragment Antibody
Single-domain Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1366CL | Mouse Anti-C5 Recombinant Antibody (TAB-1366CL) | ELISA, Inhib | Mouse IgG |
| TAB-1367CL | Mouse Anti-C5 Recombinant Antibody (TAB-1367CL) | ELISA, Inhib | Mouse IgG |
| TAB-1368CL | Mouse Anti-C5 Recombinant Antibody (TAB-1368CL) | ELISA | Mouse IgG |
| TAB-1369CL | Mouse Anti-C5 Recombinant Antibody (TAB-1369CL) | ELISA, Inhib | Mouse IgG |
| TAB-1370CL | Mouse Anti-C5 Recombinant Antibody (TAB-1370CL) | ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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