Anti-Human C5 Recombinant Antibody (TAB-453CQ) (CAT#: TAB-453CQ)

Recombinant monoclonal antibody to C5. This antibody is a human monoclonal antibody that binds specifically to C5, blocking its cleavage into C5a and C5b.

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  • Gene Expression
  • Datasheet
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SDS-PAGE

Figure 1 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SDS-PAGE

Figure 1 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SDS-PAGE

SDS-PAGE analysis of TAB-453CQ in non-reduced (right) and reduced (left) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.

SEC-HPLC

Figure 2 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SEC-HPLC

Figure 2 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in SEC-HPLC

The purity of TAB-453CQ was greater than 95% as determined by HPLC.

ELISA

Figure 3 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in ELISA

Figure 3 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in ELISA

Sandwich ELISA analysis of TAB-453CQ was performed by coating with TAB-453CQ and Recombinant Human C5 (his tag).
The secondary antibody: HRP-Anti-His tag

WB

Figure 4 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in WB

Figure 4 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in WB

Western blot analysis of TAB-453CQ was performed by loading Recombinant Human C5 (His Tag).

TAB-453CQ incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane1: Reducing antigen (0.1 μg)
Lane2: Reducing antigen (0.3 μg)
Lane3: Reducing antigen (0.6 μg)


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1, λ2
  • Specificity
  • Human C5
  • Species Reactivity
  • Human
  • Applications
  • Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
  • Conjugate
  • Unconjugated
  • Related Disease
  • Choroiditis

Product Property

  • Purity
  • > 95% as determined by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • C5D; C5a; C5b; ECLZB; CPAMD4

Related Resources

  • Biosimilar Overview
  • Related Diseases
Please refer to Tesidolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tesidolumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "C5"

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CAT Product Name Application Type
TAB-901 Anti-Human C5 Recombinant Antibody (Pexelizumab) FuncS, IF, Neut, ELISA, FC, IP, ICC scFv
TAB-008 Anti-Human C5 Recombinant Antibody (TAB-008) ELISA, FC, IP, FuncS, IF, Neut, WB IgG2 / G4 - kappa
TAB-1372CL Human Anti-C5 Recombinant Antibody (TAB-1372CL) Inhib, FuncS Humanized antibody
TAB-1373CL Human Anti-C5 Recombinant Antibody (TAB-1373CL) IB, CDC, Inhib Humanized IgG
TAB-1374CL Human Anti-C5 Recombinant Antibody (TAB-1374CL) ELISA, CDC, Inhib Humanized IgG

Customer Reviews and Q&As

Customer Review Q&As

Submit a review or a question

  • Highly specific medication
    We've seen a significant reduction in adverse effects with Tesidolumab compared to older treatments. It's a highly specific medication, which minimizes off-target issues.
  • Impressive specificity and potency
    The specificity and potency of Tesidolumab in targeting C5 are impressive. It represents a major leap forward in our ability to manage complement-mediated diseases effectively.
  • Manageable side effect
    In our trials, Tesidolumab consistently provided therapeutic benefits with a manageable side effect profile. Its role in complement inhibition cannot be overstated.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-453CQ, RRID: AB_3111952)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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