Human Anti-C5 (clone BB5.1) scFv-Fc Chimera
CAT#: VS-0125-FY95
Anti-C5 scFv-Fc is a type of antibody obtained in vitro through recombinant technology, monoclonal antibody techniques, or other synthetic biological methods. Research teams specifically clone the DNA sequences encoding the corresponding antibody fragment (scFv) and produce the fusion protein using expression systems such as viral vectors or cell cultures. This antibody can specifically bind to the C5 antigen, enhancing the sensitivity and specificity of detection in complex biological samples.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000106804-C5
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Clone
- BB5.1
- Applications
- Flow Cytometry, Immunoassay, Immunofluorescence, Immunoprecipitation, Immunohistochemistry, Functional Assay
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The function is mainly related to improving detection sensitivity and reducing background signals and contaminants.
Target
- Alternative Names
- C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement component 5, complement C5
- Gene ID
- 727
- UniProt ID
- P01031
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn741, Asn911, Asn1115, and Asn1630
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect CO5_HUMAN (1147)
Glycosylation from GlyGen 5 sites, 27 N-linked glycans (3 sites), 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001304092.1; NP_001304093.1; NP_001726.2
- Function
- Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex.
C5b has a transient binding site for C6.
The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
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Related Diseases
Systemic Lupus Erythematosus
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Clone BB5.1"
- CAT
- Product Name
See other products for "C5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-028 | Human Anti-C5 Recombinant Antibody Fab Fragment (PFBL-028) | Neut, FuncS | Human Fab |
| HPAB-602-FY-F(E) | Human Anti-C5 Recombinant Antibody; Fab Fragment (HPAB-602-FY-F(E)) | Inhib | Human Fab |
| HPAB-0080-WJ-F(E) | Human Anti-C5 Recombinant Antibody; Fab Fragment (HPAB-0080-WJ-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-1029-FY-S(P) | Human Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-1029-FY-S(P)) | ELISA | Human scFv |
| HPAB-0527-YJ-F(E) | Human Anti-C5 Recombinant Antibody; Fab Fragment (HPAB-0527-YJ-F(E)) | ELISA, Inhib, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1372CL | Human Anti-C5 Recombinant Antibody (TAB-1372CL) | Inhib, FuncS | Humanized antibody |
| TAB-1373CL | Human Anti-C5 Recombinant Antibody (TAB-1373CL) | IB, CDC, Inhib | Humanized IgG |
| TAB-1374CL | Human Anti-C5 Recombinant Antibody (TAB-1374CL) | ELISA, CDC, Inhib | Humanized IgG |
| TAB-1375CL | Human Anti-C5 Recombinant Antibody (TAB-1375CL) | CDC, Inhib | Humanized IgG |
| TAB-1373CL-S(P) | Human Anti-C5 Recombinant Antibody; scFv Fragment (TAB-1373CL-S(P)) | IB, Inhib | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1382CL | Mouse Anti-C5 Recombinant Antibody (TAB-1382CL) | ELISA, Inhib | Mouse IgG |
| TAB-1383CL | Mouse Anti-C5 Recombinant Antibody (TAB-1383CL) | ELISA, Inhib | Mouse IgG |
| TAB-1366CL-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (TAB-1366CL-S(P)) | ELISA, Inhib | Mouse scFv |
| TAB-1367CL-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (TAB-1367CL-S(P)) | ELISA, Inhib | Mouse scFv |
| TAB-1368CL-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (TAB-1368CL-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0282CT | Mouse Anti-C5 Recombinant Antibody (clone 3053) | FuncS, IHC-Fr, IHC-P, WB | Mouse IgG2a |
| HPAB-0652LY | Mouse Anti-C5 Recombinant Antibody (HPAB-0652LY) | IP, RIA, ELISA, WB | Mouse IgG |
| PABC-462 | Human Anti-C5 Recombinant Antibody (PABC-462) | WB, HA, ELISA, FC, Neut | Human IgG1, κ |
| HPAB-1484-FY | Mouse Anti-C5 Recombinant Antibody (HPAB-1484-FY) | ELISA, Neut | Mouse IgG |
| HPAB-1485-FY | Mouse Anti-C5 Recombinant Antibody (HPAB-1485-FY) | ELISA, Neut | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-082CQ | Mouse Anti-C5 Recombinant Antibody (clone CBL249) | ELISA, Neut | Mouse IgG2a |
| NEUT-083CQ | Mouse Anti-C5 Recombinant Antibody (clone MM0608-6H13) | ELISA, Neut, WB | Mouse IgG1 |
| NEUT-084CQ | Mouse Anti-C5 Recombinant Antibody (clone CBL030) | ELISA, WB, Neut | Mouse IgG1 |
| NEUT-085CQ | Mouse Anti-C5 Recombinant Antibody (clone CBL250) | ELISA, WB, IHC, FuncS | Mouse IgG1 |
| NEUT-086CQ | Mouse Anti-C5 Recombinant Antibody (clone G25/2) | ELISA, IP, WB, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-088CQ | Mouse Anti-C5 Recombinant Antibody (clone CBL771) | WB, Block, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4104 | Hi-Affi™ Rabbit Anti-C5 Recombinant Antibody (clone SI175DS) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-453CQ | Anti-Human C5 Recombinant Antibody (TAB-453CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, λ2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127CQ-S(P) | Human Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-0127CQ-S(P)) | ELISA, WB, Inhib, FuncS | Human scFv |
| HPAB-M0016-YC-S(P) | Rabbit Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-M0016-YC-S(P)) | ELISA | Rabbit scFv |
| HPAB-M0017-YC-S(P) | Rabbit Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-M0017-YC-S(P)) | ELISA | Rabbit scFv |
| HPAB-M0018-YC-S(P) | Human Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-M0018-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-1484-FY-F(E) | Mouse Anti-C5 Recombinant Antibody; Fab Fragment (HPAB-1484-FY-F(E)) | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-559 | Recombinant Llama Anti-C5 Single Domain Antibody (PABC-559) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-453CQ | Afuco™ Anti-C5 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-453CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-008 | Afuco™ Anti-C5 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-008) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-436CQ | Afuco™ Anti-C5 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-436CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY36 | AbPlus™ Anti-C5 Magnetic Beads (5G1.1CB) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC103 | Human Anti-C5 Recombinant Antibody Hexamer (VS-0924-YC103), CDC Enhanced | IB, CDC, Inhib | Antibody hexamer |
| VS-0924-YC104 | Mouse Anti-C5 Recombinant Antibody Hexamer (VS-0924-YC104), CDC Enhanced | ELISA, Inhib, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY137 | Mouse Anti-NHP C5 Recombinant Antibody (clone aE11) | ELISA | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY889 | Anti-C5 Immunohistochemistry Kit | IHC | |
| VS-0525-XY890 | Anti-Rat C5 Immunohistochemistry Kit | IHC |
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