Human Anti-CD47 Recombinant Antibody (clone ZFlY1-93Y94P); Fab Fragment
CAT#: HPAB-N0037-YC-F(E)
The antibody can effectively block the binding of CD47 to SIRP alpha, and promote the phagocytosis of immune cells to tumor cells, and has a clear therapeutic effect on leukemia model mice with CD47 positive expression, and has a significant synergistic effect in combination with targeted drugs such as EGFR.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16055/204_F3_1_selected.jpg
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human CD47
- Species Reactivity
- Human
- Clone
- ZFlY1-93Y94P
- Applications
- ELISA, FC, Block
- Related Disease
- Atherosclerosis, Inflammation
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD47 Molecule; Antigenic Surface Determinant Protein OA3; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer); Antigen Identified By Monoclonal Antibody 1D8; Leukocyte Surface Antigen CD47; Integrin Associated Protein; Rh-Related Antigen; CD47 Glycoprotein
- Gene ID
- 961
- UniProt ID
- Q08722
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone ZFlY1-93Y94P"
- CAT
- Product Name
See other products for "CD47"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-278LC | Human Anti-CD47 Recombinant Antibody (TAB-278LC) | Block, FuncS | Human IgG, κ |
| TAB-279LC | Human Anti-CD47 Recombinant Antibody (TAB-279LC) | Block, FuncS | Human IgG, κ |
| TAB-278LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-278LC-S(P)) | ELISA | Human scFv |
| TAB-279LC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (TAB-279LC-S(P)) | ELISA | Human scFv |
| TAB-278LC-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (TAB-278LC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-280LC | Human Anti-CD47 Recombinant Antibody (TAB-280LC) | ELISA | Humanized antibody |
| TAB-281LC | Human Anti-CD47 Recombinant Antibody (TAB-281LC) | ELISA | Humanized antibody |
| TAB-282LC | Human Anti-CD47 Recombinant Antibody (TAB-282LC) | ELISA | Humanized antibody |
| TAB-283LC | Human Anti-CD47 Recombinant Antibody (TAB-283LC) | ELISA | Humanized antibody |
| TAB-284LC | Human Anti-CD47 Recombinant Antibody (TAB-284LC) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0505CT | Mouse Anti-CD47 Recombinant Antibody (clone C7I23.3) | FC, FuncS, IF, IP, WB | Mouse IgG1 |
| HPAB-0008-FY | Human Anti-CD47 Recombinant Antibody (HPAB-0008-FY) | ELISA, PD, Activ, PK, Stim | Humanized IgG |
| PABC-464 | Mouse Anti-CD47 Recombinant Antibody (clone B6H12.2) | IF, FuncS, FC, WB, IP, Neut, IHC | Mouse IgG1, κ |
| HPAB-0676YY | Human Anti-CD47 Recombinant Antibody (HPAB-0676YY) | FC, Inhib, ELISA | Humanized IgG |
| FAMAB-1647CQ | Mouse Anti-CD47 Recombinant Antibody (clone OX101) | IP, WB, Block, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-387CQ | Mouse Anti-CD47 Recombinant Antibody (clone CBL377) | Block, FC, CyTOF | Mouse IgG1 |
| NEUT-388CQ | Mouse Anti-CD47 Recombinant Antibody (clone MIAP410) | Block, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-389CQ | Rat Anti-CD47 Recombinant Antibody (clone miap301) | FC, FuncS, Neut, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0565 | Hi-Affi™ Rabbit Anti-CD47 Recombinant Antibody (clone DS565AB) | WB, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0331-YC-S(P) | Mouse Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-N0331-YC-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-N0332-YC-S(P) | Mouse Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-N0332-YC-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-N0333-YC-S(P) | Mouse Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-N0333-YC-S(P)) | ELISA, FC, Block | Mouse scFv |
| HPAB-N0334-YC-S(P) | Human Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-N0334-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-N0335-YC-S(P) | Mouse Anti-CD47 Recombinant Antibody; scFv Fragment (HPAB-N0335-YC-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1088LY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-1088LY-F(E)) | ELISA | Human Fab |
| HPAB-1089LY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-1089LY-F(E)) | ELISA | Human Fab |
| HPAB-1090LY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-1090LY-F(E)) | ELISA | Human Fab |
| HPAB-1091LY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-1091LY-F(E)) | ELISA | Human Fab |
| HPAB-1092LY-F(E) | Human Anti-CD47 Recombinant Antibody; Fab Fragment (HPAB-1092LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0310-CN | Mouse Anti-CD47 Recombinant Antibody (clone 1A9) | IF, IHC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP496-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP496-YC) | FC, BL, FuncS | Alpaca VHH |
| HPAB-AP497-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP497-YC) | FC | Alpaca VHH |
| HPAB-AP498-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP498-YC) | FC, BL | Alpaca VHH |
| HPAB-AP499-YC | Recombinant Alpaca Anti-CD47 Single Domain Antibody (HPAB-AP499-YC) | FC, BL | Alpaca VHH |
| NBD-0016-YJ-VHH | Camelid Anti-CD47 Recombinant Single Domain Antibody (NBD-0016-YJ-VHH) | ELISA, SPR | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY99 | Mouse Anti-NHP CD47 Recombinant Antibody (clone MEM-122) | FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY55 | CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone B6H12) | FC | Mouse IgG1, kappa |
| VS-0225-XY56 | CytoStream™ Mouse Anti-CD47 Recombinant Antibody (clone CC2C6) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC635 | Recombinant Anti-CD47 Vesicular Antibody, EV Displayed (VS-0425-YC635) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1191 | Anti-CD47 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1192 | Anti-Human CD47 Immunohistochemistry Kit | IHC |
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