Rabbit Anti-CTLA4 Recombinant Antibody (VS-1125-XY244)
CAT#: VS-1125-XY244
Engineered for cell therapy and companion diagnostics, this CTLA4 antibody supports ELISA (concentration measurement) and FC (cell phenotyping) on live ovarian cancer cells and frozen hepatocellular carcinoma tissues. Its compatibility with fluorescent dyes improves signal clarity in FC assays.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
❮
❯
Specifications
- Host Animal
- Rabbit
- Applications
- FC, SPR
- Specificity
- CTLA4
- Target
- CTLA4
- Species Reactivity
- Human
- Type
- Rabbit IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Liquid
- Buffer
- PBS, pH 7.3
- Preservative
- 0.09% sodium azide
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is an immune checkpoint receptor expressed on activated T cells and regulatory T cells (Tregs). It competes with CD28 for binding to B7 ligands (CD80/CD86) on antigen-presenting cells (APCs), suppressing T cell activation and limiting immune responses to self-antigens. Tumors exploit CTLA4 to evade anti-tumor immunity. Monoclonal antibodies blocking CTLA4 (ipilimumab, tremelimumab) enhance T cell activation and expansion, unleashing anti-tumor immunity. Approved for melanoma, renal cell carcinoma (RCC), and colorectal cancer, CTLA4 inhibitors are often combined with PD-1/PD-L1 blockers for synergistic efficacy.
- Alternative Names
- ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
- Gene ID
- 1493
- UniProt ID
- P16410
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Related Diseases
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-986 | Recombinant Mouse Anti-Human CTLA4 Antibody F(ab')2 Fragment, clone ANC152.2/8H5 | FC, EIA, FX, Bios | F(ab')2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-987 | Mouse Anti-CTLA4 Recombinant Antibody (clone ANC152.2/8H5); Fab Fragment | FC, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-067 | Anti-Human CTLA4 Recombinant Antibody (TAB-067) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-206 | Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab)) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G015E | Anti-CTLA4 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G015S | Anti-CTLA4 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G015M | Anti-CTLA4 immunotoxin (scFv)-Mel | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-195CL | Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-083MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.H) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-084MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2422.H) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-085MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-086MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-087MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-087MZ) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-088MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-088MZ) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-089MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-089MZ) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-090MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-090MZ) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-091MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-091MZ) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-092MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-092MZ) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-093MZ | Anti-Human CTLA4 Recombinant Antibody (Mu-26B) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-085MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-086MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-087MZ-S(P) | Mouse Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-087MZ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-085MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1734MZ | Recombinant Mouse Anti-Human CTLA4 Antibody (clone COJ4) | FC, ICC, IHC-Fr | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-567CQ | Mouse Anti-CTLA4 Recombinant Antibody (NEUT-567CQ) | FC, FuncS, Neut, IP, WB | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-568CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone L3D10) | FC, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-569CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone AS32) | WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-570CQ | Human Anti-CTLA4 Recombinant Antibody (clone YC030) | Neut | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-571CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone BN13) | Block, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-572CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4B9) | FC, Block, ELISA, IP | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-573CQ | Rat Anti-Ctla4 Recombinant Antibody (clone 63828) | WB, FC, Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-577CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone MAB0835) | Block, FC | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-578CQ | Hamster Anti-Ctla4 Recombinant Antibody (NEUT-578CQ) | Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-579CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone 9H10) | FC, Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0855 | Hi-Affi™ Rabbit Anti-CTLA4 Recombinant Antibody (clone DS855AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0051-YC | Human Anti-CTLA4 Recombinant Antibody (clone 10D1) | ELISA, Cyt, Block | Human IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0051-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody (clone 10D1); scFv Fragment | ELISA, Cyt, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0051-YC-F(E) | Human Anti-CTLA4 Recombinant Antibody (clone 10D1); Fab Fragment | ELISA, Cyt, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-006LC | Hamster Anti-Ctla4 Recombinant Antibody (clone YC082) | ELISA, FC | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-061LC | Human Anti-CTLA4 Recombinant Antibody (MOB-061LC) | ELISA, WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157-FY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0157-FY) | Activ | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157-FY-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0157-FY-S(P)) | Activ | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157-FY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0157-FY-F(E)) | Activ | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0343-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-N0343-YC-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0343-YC-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-N0343-YC-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0749LY-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0749LY-S(P)) | FuncS, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0750LY-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0750LY-S(P)) | FuncS, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-067 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-067) | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-206 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-206) | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP860-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP860-YC) | ELISA, Block | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP861-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP861-YC) | ELISA, Block | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP862-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP862-YC) | ELISA, Block | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP863-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP863-YC) | ELISA, Block | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP864-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP864-YC) | ELISA, Block | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY22 | Mouse Anti-CTLA4 Agonistic Antibody (VS-0724-XY22) | WB, Agonistic assays | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY73 | AbPlus™ Anti-CTLA4 Magnetic Beads (14D3) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY92 | CytoStream™ Mouse Anti-CTLA4 Recombinant Antibody (clone BNI3) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY93 | CytoStream™ Armenian Hamster Anti-CTLA4 Recombinant Antibody (clone UC10-4F10-11) | FC, IP | Armenian Hamster IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY63 | Human Anti-CTLA4 (clone JMW-3B3) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC558 | Recombinant Anti-CTLA4 Vesicular Antibody, EV Displayed (VS-0425-YC558) | ELISA, FC, SPR, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1763 | Anti-CTLA4 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1764 | Anti-Mouse CTLA4 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC87 | SmartAb™ Recombinant Anti-CTLA4 pH-dependent Antibody (VS-0825-YC87) | WB, IF, Neut, ELISA, FC, IP | Human IgG1 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1025-YC10 | Anti-CTLA4 Antibody Prodrug, Protease Activated (Ticilimumab) | ISZ, Cyt, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1025-YC196 | Anti-CTLA4 Antibody Prodrug, Protease Activated (10D1) | ISZ, Cyt, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY239 | Human Anti-CTLA4 Recombinant Antibody (VS-1125-XY239) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY240 | Rabbit Anti-CTLA4 Recombinant Antibody (VS-1125-XY240) | IHC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY241 | Rabbit Anti-CTLA4 Recombinant Antibody (VS-1125-XY241) | IHC | Rabbit IgG, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY242 | Rabbit Anti-CTLA4 Recombinant Antibody (VS-1125-XY242) | IHC | Rabbit IgG, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY243 | Rabbit Anti-CTLA4 Recombinant Antibody (VS-1125-XY243) | IHC | Rabbit IgG, kappa |
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