AbPlus™ Anti-F8 Magnetic Beads (JM4)
CAT#: VS-0424-XY94
The AbPlus Anti-F8 Magnetic Beads (JM4) is an innovative affinity resin which is bound with anti-F8 specific antibody (JM4). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of F8 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
Normal Tissue
Figure 3 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
RNA Expression
Figure 4 RNA cell line category:Cell line enhanced (U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-F8 specific antibody (JM4)
- Target
- F8
- Immunogen
- Recombinant F8
- Target Species
- Human
- Antibody Clone
- JM4
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
- Alternative Names
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E
- Gene ID
- 2157
- UniProt ID
- P00451
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
| PABL-051 | Mouse Anti-F8 Recombinant Antibody (clone 3E6) | ELISA, WB, FuncS | Mouse IgG |
| PABL-052 | Mouse Anti-F8 Recombinant Antibody (clone G99) | ELISA, WB, FuncS | Mouse IgG |
| HPAB-1979-FY | Human Anti-F8 Recombinant Antibody (clone WR8) | IP | Human IgG4 |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-015LC | Recombinant Anti-Human F8 Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
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| PABX-058 | Recombinant Human Anti-F8 Antibody (BO2C11) | WB, ELISA, FuncS, Inhib, PK, IP, SPR | IgG |
| PABX-058-S (P) | Recombinant Human Anti-F8 Antibody scFv Fragment (BO2C11) | WB, ELISA, FuncS | scFv |
| PABX-058-F (E) | Recombinant Human Anti-F8 Antibody Fab Fragment (BO2C11) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-765CQ | Mouse Anti-F8 Recombinant Antibody (clone CBL215) | ELISA, WB, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1229 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone DS1229AB) | ELISA | Rabbit IgG |
| MOR-4166 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI243DS) | ELISA | Rabbit IgG |
| MOR-4167 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI244DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0611LC | Human Anti-F8 Recombinant Antibody (clone BO2C11) | ELISA | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1242WJ-S(P) | Human Anti-F8 Recombinant Antibody (clone YK3.3.40); scFv Fragment | ELISA | Human scFv |
| HPAB-1243WJ-S(P) | Human Anti-F8 Recombinant Antibody (clone YK3.3.50); scFv Fragment | ELISA | Human scFv |
| HPAB-1979-FY-S(P) | Human Anti-F8 Recombinant Antibody (clone WR8); scFv Fragment | IP | Human scFv |
| HPAB-1980-FY-S(P) | Human Anti-F8 Recombinant Antibody (clone WR11); scFv Fragment | IP | Human scFv |
| HPAB-1981-FY-S(P) | Human Anti-F8 Recombinant Antibody (clone WR10); scFv Fragment | IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1979-FY-F(E) | Human Anti-F8 Recombinant Antibody (clone WR8); Fab Fragment | IP | Human Fab |
| HPAB-1980-FY-F(E) | Human Anti-F8 Recombinant Antibody (clone WR11); Fab Fragment | IP | Human Fab |
| HPAB-1981-FY-F(E) | Human Anti-F8 Recombinant Antibody (clone WR10); Fab Fragment | IP | Human Fab |
| FAMAB-0037JF-F(E) | Human Anti-F8 Recombinant Antibody (clone MH8); Fab Fragment | IP, ELISA, FuncS | Human Fab |
| FAMAB-0038JF-F(E) | Human Anti-F8 Recombinant Antibody (clone DH10); Fab Fragment | IP, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
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| MHC-YF075 | DRB1*11:01/Factor VIII Factor VIII (ENIQRFLPNPAGVQLEDPEF) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY172 | Human Anti-F8 (clone BO2C11) scFv-Fc Chimera | Inhib, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC76 | Recombinant Anti-F8 (A2 domain x C1 domain) Biparatopic Antibody, Tandem scFv (Clone JM4 x Clone KM33) | ELISA | Tandem scFv |
| VS-0525-YC78 | Recombinant Anti-F8 (AA 484-508 x AA 712-736) Biparatopic Antibody, Tandem scFv (Clone VK34 x Clone VK41) | ELISA | Tandem scFv |
| VS-0525-YC80 | Recombinant Anti-F8 (AA 1803-1818 x AA 2223-2332) Biparatopic Antibody, Tandem scFv (Clone KM41 x Clone WR8) | ELISA | Tandem scFv |
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