DRB1*11:01/Factor VIII Factor VIII (ENIQRFLPNPAGVQLEDPEF) MHC Monomer (CAT#: MHC-YF075)
This product is a MHC monomer of biotinylated peptide/MHC complex composed Factor VIII-derived peptide of ENIQRFLPNPAGVQLEDPEF sequence covering 589–608 and DRB1*11:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
Figure 4 RNA cell line category:Cell line enhanced (U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
Specifications
- Allele
- DRB1*11:01
- Class
- Class II
- Antigen
- Factor VIII
- Antigen Species
- Factor VIII
- Peptide
- ENIQRFLPNPAGVQLEDPEF
- Range
- 589–608
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
- Alternative Names
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E
- Gene ID
- 2157
- UniProt ID
- P00451
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "F8"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-930-VHH | Recombinant Anti-Human F8 VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-259CL | Human Anti-F8 Recombinant Antibody (TAB-259CL) | ELISA | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-016WM | Anti-Human F8 Recombinant Antibody (BOIIB2) | Inhib, ELISA | |
| TAB-017WM | Anti-Human F8 Recombinant Antibody (4F50) | ELISA | |
| TAB-016WM-S(P) | Anti-Human F8 Recombinant Antibody scFv Fragment (BOIIB2) | ELISA | |
| TAB-016WM-F(E) | Anti-Human F8 Recombinant Antibody Fab Fragment (BOIIB2) | ELISA | |
| TAB-017WM-F(E) | Anti-Human F8 Recombinant Antibody Fab Fragment (4F50) | ELISA |
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-014LC | Recombinant Anti-Human F8 Antibody (Fab glycosylation) | ELISA | Human antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-015LC | Recombinant Anti-Human F8 Antibody (Non-glycosylated) | ELISA | Human antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-058 | Recombinant Human Anti-F8 Antibody (BO2C11) | WB, ELISA, FuncS, Inhib, PK, IP, SPR | IgG |
| PABX-058-S (P) | Recombinant Human Anti-F8 Antibody scFv Fragment (BO2C11) | WB, ELISA, FuncS | scFv |
| PABX-058-F (E) | Recombinant Human Anti-F8 Antibody Fab Fragment (BO2C11) | WB, ELISA, FuncS | Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-765CQ | Mouse Anti-F8 Recombinant Antibody (clone CBL215) | ELISA, WB, Neut | Mouse IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1229 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone DS1229AB) | ELISA | Rabbit IgG |
| MOR-4166 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI243DS) | ELISA | Rabbit IgG |
| MOR-4167 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI244DS) | ELISA | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0611LC | Human Anti-F8 Recombinant Antibody (clone BO2C11) | ELISA | Human IgG4 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0096-YC | Human Anti-F8 Recombinant Antibody (clone YK3.3.38) | ELISA, FuncS | Human IgG |
| FAMAB-0037JF | Human Anti-F8 Recombinant Antibody (clone MH8) | WB, IF, IHC, Inhib, FuncS | Human IgG |
| FAMAB-0038JF | Human Anti-F8 Recombinant Antibody (clone DH10) | WB, IF, ELISA, Dot | Human IgG |
| FAMAB-0039JF | Human Anti-F8 Recombinant Antibody (clone JM4) | IP, ELISA, FuncS | Human IgG |
| FAMAB-0200JF | Human Anti-F8 Recombinant Antibody (clone KM41) | WB, ELISA, FuncS | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0096-YC-F(E) | Human Anti-F8 Recombinant Antibody (clone YK3.3.38); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-0178CQ-F(E) | Mouse Anti-F8 Recombinant Antibody; Fab Fragment (HPAB-0178CQ-F(E)) | ELISA, DB, Inhib | Mouse Fab |
| HPAB-1242WJ-F(E) | Human Anti-F8 Recombinant Antibody (clone YK3.3.40); Fab Fragment | ELISA | Human Fab |
| HPAB-1243WJ-F(E) | Human Anti-F8 Recombinant Antibody (clone YK3.3.50); Fab Fragment | ELISA | Human Fab |
| HPAB-1977-FY-F(E) | Human Anti-F8 Recombinant Antibody (clone 92-137); Fab Fragment | Inhib | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0178CQ-S(P) | Mouse Anti-F8 Recombinant Antibody; scFv Fragment (HPAB-0178CQ-S(P)) | ELISA, DB, Inhib | Mouse scFv |
| HPAB-1242WJ-S(P) | Human Anti-F8 Recombinant Antibody (clone YK3.3.40); scFv Fragment | ELISA | Human scFv |
| HPAB-1243WJ-S(P) | Human Anti-F8 Recombinant Antibody (clone YK3.3.50); scFv Fragment | ELISA | Human scFv |
| FAMAB-0201JF-S(P) | Human Anti-F8 Recombinant Antibody (clone KM38); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0287JF-S(P) | Human Anti-F8 Recombinant Antibody (clone VK41); scFv Fragment | ELISA, FuncS | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-YF075. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.