Anti-Human F8 Recombinant Antibody (BOIIB2) (CAT#: TAB-016WM)
Human inhibitory anti-factor viii antibody BOIIB2 binding to the a2 domain was kdiss evaluated as 1 x 10-8 s-1 and the kass as 1 x 103 M-1s-1. This antibody can be potentially used for preventing and treating cardiovascular disorders.
Specific Inquiry
Inhib
Figure 1 Determination of inhibitor titers.
The residual FVIII:C from representative experiments is shown. Inhibitor titers were defined by dilution of inhibitor samples until 50% of the initial FVIII:C was neutralized.
Shi, Q., Kuether, E. L., Schroeder, J. A., Perry, C. L., Fahs, S. A., Cox Gill, J., & Montgomery, R. R. (2012). Factor VIII inhibitors: von willebrand factor makes a difference in vitro and in vivo. Journal of Thrombosis and Haemostasis, 10(11), 2328-2337.
Specifications
- Immunogen
- Human FVIII
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- BOIIB2
- Applications
- Inhib, ELISA
- Related Disease
- Cardiovascular disorders
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E; F8; coagulation factor VIII
- Gene ID
- 2157
- UniProt ID
- P00451
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-930-VHH | Recombinant Anti-Human F8 VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-259CL | Human Anti-F8 Recombinant Antibody (TAB-259CL) | ELISA | Human IgG |
Mouse Antibody
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-014LC | Recombinant Anti-Human F8 Antibody (Fab glycosylation) | ELISA | Human antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-015LC | Recombinant Anti-Human F8 Antibody (Non-glycosylated) | ELISA | Human antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-058 | Recombinant Human Anti-F8 Antibody (BO2C11) | WB, ELISA, FuncS, Inhib, PK, IP, SPR | IgG |
| PABX-058-S (P) | Recombinant Human Anti-F8 Antibody scFv Fragment (BO2C11) | WB, ELISA, FuncS | scFv |
| PABX-058-F (E) | Recombinant Human Anti-F8 Antibody Fab Fragment (BO2C11) | WB, ELISA, FuncS | Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-765CQ | Mouse Anti-F8 Recombinant Antibody (clone CBL215) | ELISA, WB, Neut | Mouse IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1229 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone DS1229AB) | ELISA | Rabbit IgG |
| MOR-4166 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI243DS) | ELISA | Rabbit IgG |
| MOR-4167 | Hi-Affi™ Rabbit Anti-F8 Recombinant Antibody (clone SI244DS) | ELISA | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0611LC | Human Anti-F8 Recombinant Antibody (clone BO2C11) | ELISA | Human IgG4 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0096-YC | Human Anti-F8 Recombinant Antibody (clone YK3.3.38) | ELISA, FuncS | Human IgG |
| FAMAB-0197-CN | Human Anti-F8 Recombinant Antibody (clone KM33) | WB | Human IgG |
| HPAB-1242WJ | Human Anti-F8 Recombinant Antibody (clone YK3.3.40) | Inhib | Human IgG |
| HPAB-1243WJ | Human Anti-F8 Recombinant Antibody (clone YK3.3.50) | Inhib | Human IgG |
| HPAB-1977-FY | Human Anti-F8 Recombinant Antibody (clone 92-137) | Inhib | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0197-CN-S(P) | Human Anti-F8 Recombinant Antibody (clone KM33); scFv Fragment | WB | Human scFv |
| FAMAB-0037JF-S(P) | Human Anti-F8 Recombinant Antibody (clone MH8); scFv Fragment | IP, ELISA, FuncS | Human scFv |
| FAMAB-0038JF-S(P) | Human Anti-F8 Recombinant Antibody (clone DH10); scFv Fragment | IP, ELISA, FuncS | Human scFv |
| FAMAB-0039JF-S(P) | Human Anti-F8 Recombinant Antibody (clone JM4); scFv Fragment | IP, ELISA, FuncS | Human scFv |
| FAMAB-0287JF-S(P) | Human Anti-F8 Recombinant Antibody (clone VK41); scFv Fragment | ELISA, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0793-FY-S(P) | Mouse Anti-F8 Recombinant Antibody (clone 4F143); Fab Fragment | Activ | Mouse Fab |
| HPAB-0794-FY-S(P) | Mouse Anti-F8 Recombinant Antibody (clone 4F50); Fab Fragment | Activ | Mouse Fab |
| HPAB-1242WJ-F(E) | Human Anti-F8 Recombinant Antibody (clone YK3.3.40); Fab Fragment | ELISA | Human Fab |
| HPAB-1243WJ-F(E) | Human Anti-F8 Recombinant Antibody (clone YK3.3.50); Fab Fragment | ELISA | Human Fab |
| HPAB-1977-FY-F(E) | Human Anti-F8 Recombinant Antibody (clone 92-137); Fab Fragment | Inhib | Human Fab |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF075 | DRB1*11:01/Factor VIII Factor VIII (ENIQRFLPNPAGVQLEDPEF) MHC Monomer | MHC Multimer |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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