Human Anti-HIV-1 Recombinant Antibody (clone 9F11) (CAT#: HPAB-1989-FY)

This product is a recombinant antibody that recognizes HIV-1. The monoclonal antibody 9F11 reacts with the epitope of HIV-1.


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FC

Figure 1 Shows specificity of 9F11 antibody.

Figure 1 Shows specificity of 9F11 antibody.

The result of flow cytometory analysis shows that HIV-infected cells are stained with 9F11 antibodies while non-infected cells are not.

FC

Figure 2 Shows specificity of 9F11 antibody to peripheral blood lymphocytes.

Figure 2 Shows specificity of 9F11 antibody to peripheral blood lymphocytes.

The drawing shows that 9F11 antibody reacts with the activated lymphocytes stimulated with PHA while it does not react with normal peripheral blood lymphocytes (PBMC: peripheral blood lymphocyte).

CMCD

Figure 3 Shows a cell impairing reaction by 9F11 antibody under mediation by the complement.

Figure 3 Shows a cell impairing reaction by 9F11 antibody under mediation by the complement.

Almost all cells are destroyed 4 hours after addition of 2 µg/ml of 9F11 antibody and fresh human serum (including a complement component) to HIV-1 infected cells MOLT-4/IIIB. No effects have been observed at all when the serum is not added or on non-infected cells MOLT-4.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgM
  • Specificity
  • HIV-1
  • Species Reactivity
  • HIV
  • Clone
  • 9F11
  • Applications
  • FC, CMCD
  • Related Disease
  • HIV

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 antibody has been reported in applications of Flow Cytometry, Complement Mediated Cell Depletion.

Target

  • Alternative Names
  • HIV-1; Human immunodeficiency virus-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Single-domain Antibody

CAT Product Name Application Type
NAB-1889-sdAb Recombinant Anti-HIV-1 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH
PNBL-038 Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (PNBL-038) WB, FuncS Llama VHH

Humanized Antibody

Immunotoxin

CAT Product Name Application Type
AGTO-G037E Anti-HIV-1 immunotoxin 3B3 (scFv)-PE Cytotoxicity assay, Function study
AGTO-G037D Anti-HIV-1 immunotoxin 3B3 (scFv)-DT Cytotoxicity assay, Function study

Chimeric Antibody

CAT Product Name Application Type
PABX-093-S (P) Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab28) WB, ELISA, FuncS scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4221 Rabbit Anti-HIV-1 Recombinant Antibody (clone SI300DS) ELISA, ICC, IF, FC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-068 Afuco™ Anti-HIV-1 ADCC Recombinant Antibody (Suvizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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