The monoclonal antibody is provided to human before or after human body is infected with virus and can be subjected to neutralization reaction with virus, so as to effectively inhibit or prevent virus from infecting human T lymphocyte.
Figure 1 Synergy of MAb for binding to the infected CD4 T cells.
The results represent the average ± SEM of the results obtained in four experiments.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
Figure 2 ADCC synergy with combinations of MAbs.
The graphs represent the average ± SEM of the results obtained in three experiments with each run in duplicate.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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