Human Anti-HIV-1 Recombinant Antibody (clone A2) (CAT#: HPAB-AP363-YC)
The monoclonal antibody is provided to human before or after human body is infected with virus and can be subjected to neutralization reaction with virus, so as to effectively inhibit or prevent virus from infecting human T lymphocyte.
Specific Inquiry
FC
Figure 1 Synergy of MAb for binding to the infected CD4 T cells.
The results represent the average ± SEM of the results obtained in four experiments.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
FuncS
Figure 2 ADCC synergy with combinations of MAbs.
The graphs represent the average ± SEM of the results obtained in three experiments with each run in duplicate.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HIV1
- Species Reactivity
- HIV-1
- Clone
- A2
- Applications
- FuncS, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV1 antibody has been reported in applications of Functional Assay, Flow Cytometry.
Target
- Alternative Names
- Human immunodeficiency viruse 1; HIV-1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone A2"
See other products for "HIV-1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1889-sdAb | Recombinant Anti-HIV-1 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| PNBL-038 | Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (A12) | WB, FuncS | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-068 | Anti-HIV-1 Recombinant Antibody (Suvizumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| PABX-094-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (Fab4025) | WB, ELISA, FuncS | scFv |
| PABX-099-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment | FC, FuncS | scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G037E | Anti-HIV-1 immunotoxin 3B3 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G037D | Anti-HIV-1 immunotoxin 3B3 (scFv)-DT | Cytotoxicity assay, Function study |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-140 | Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25) | WB, ELISA, Neut, FuncS | Human IgG1 |
| MRO-770CQ | Mouse Anti-HIV-1 Recombinant Antibody (clone 10 (03-002)) | EIA, WB, IHC, IP | Mouse IgG1 |
| VS-0423-XY28 | Human Anti-HIV-1 Recombinant Antibody (clone sb1) | ELISA | Human IgG |
| VS-0423-XY37 | Human Anti-HIV-1 Recombinant Antibody (clone HBL-2) | ELISA | Human IgM |
| VS-0423-XY38 | Human Anti-HIV-1 Recombinant Antibody (clone HBL-3) | ELISA | Human IgM |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-140 | Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| FAMAB-0176CQ-F(E) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-0158-YJ-F(E) | Human Anti-HIV-1 Recombinant Antibody; Fab Fragment (HPAB-0158-YJ-F(E)) | ELISA, Neut, Inhib | Human Fab |
| HPAB-AP363-YC-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone A2); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-1988-FY-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); Fab Fragment | FC, ELISA | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-001 | Recombinant Human Anti-HIV-1 Antibody (1281) | WB, FuncS, Neut, SPR | IgG |
| PABX-090 | Recombinant Human Anti-HIV-1 Antibody (CH04H/CH02L) | Neut, FuncS | IgG |
| PABX-095-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab59.1) | Neut, ELISA, FuncS | scFv |
| PABX-001-F (E) | Recombinant Human Anti-HIV-1 Antibody Fab Fragment (1281) | WB, FuncS | Fab |
| PABX-087-F(E) | Human Anti-HIV-1 Recombinant Antibody; Fab Fragment (PABX-087-F(E)) | WB, ELISA, FuncS | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-008 | Recombinant Mouse Anti-HIV-1 Antibody | WB, IHC, IF, FuncS | IgG |
| PABX-001-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (1281) | WB, FuncS | scFv |
| PABX-096-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (N12-i15) | WB, ELISA, IF, FuncS | scFv |
| PABX-008-F (E) | Recombinant Mouse Anti-HIV-1 Antibody Fab Fragment | WB, IHC, IF, FuncS | Fab |
| PABX-087-S(P) | Human Anti-HIV-1 Recombinant Antibody; scFv Fragment (PABX-087-S(P)) | WB, ELISA, FuncS | Human scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-093-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab28) | WB, ELISA, FuncS | scFv |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1376 | PE-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
| MHC-LC1377 | APC-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
| MHC-LC1378 | BV421-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4221 | Rabbit Anti-HIV-1 Recombinant Antibody (clone SI300DS) | ELISA, ICC, IF, FC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0176CQ-S(P) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-0158-YJ-S(P) | Mouse Anti-HIV-1 Recombinant Antibody; scFv Fragment (HPAB-0158-YJ-S(P)) | ELISA, Neut, Inhib | Mouse scFv |
| HPAB-AP363-YC-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone A2); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-1988-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); scFv Fragment | FC, ELISA | Human scFv |
| HPAB-1989-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 9F11); scFv Fragment | FC, ELISA | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-068 | Afuco™ Anti-HIV-1 ADCC Recombinant Antibody (Suvizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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