Human Anti-HIV-1 Recombinant Antibody (clone A2) (CAT#: HPAB-AP363-YC)
The monoclonal antibody is provided to human before or after human body is infected with virus and can be subjected to neutralization reaction with virus, so as to effectively inhibit or prevent virus from infecting human T lymphocyte.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Synergy of MAb for binding to the infected CD4 T cells.
The results represent the average ± SEM of the results obtained in four experiments.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
Figure 2 ADCC synergy with combinations of MAbs.
The graphs represent the average ± SEM of the results obtained in three experiments with each run in duplicate.
Pollara, J., Bonsignori, M., Moody, M. A., Liu, P., Alam, S. M., Hwang, K. K., ... & Whitesides, J. F. (2014). HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities. Journal of virology , 88 (14), 7715-7726.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HIV1
- Species Reactivity
- HIV-1
- Clone
- A2
- Applications
- FuncS, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV1 antibody has been reported in applications of Functional Assay, Flow Cytometry.
Target
- Alternative Names
- Human immunodeficiency viruse 1; HIV-1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
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NAB-1889-sdAb | Recombinant Anti-HIV-1 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
PNBL-038 | Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (PNBL-038) | WB, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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