Human Anti-IFNAR1 Recombinant Antibody (clone H2K1) (CAT#: HPAB-J0127-YC)
Provided is a humanized antibody which bind to interferon alpha receptor-1 (IFNAR1). The antibody can be used to some applications including ELISA, Flow cytometry and inhibition.
Specific Inquiry
FC
Figure 1 Ex vivo analysis. Spleen cells from BXSB mice (16 wk old, n = 3) were examined by flow cytometry to assess cell-surface IFNAR expression after gating on various cells.
Background staining (gray-lined histograms) and IFNAR levels in noncultured ex vivo B cells (gray-filled histograms) are also depicted.
Baccala, R., Gonzalez-Quintial, R., Schreiber, R. D., Lawson, B. R., Kono, D. H., & Theofilopoulos, A. N. (2012). Anti–IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice. The Journal of Immunology, 189(12), 5976-5984.
ELISA
Figure 2 Effects of IFNAR blockade in DC subsets.
Bars represent average of individual mice (n = 3).
Baccala, R., Gonzalez-Quintial, R., Schreiber, R. D., Lawson, B. R., Kono, D. H., & Theofilopoulos, A. N. (2012). Anti–IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice. The Journal of Immunology, 189(12), 5976-5984.
IHC
Figure 3 Late anti–IFNAR Ab treatment of BXSB mice.
Kidney glomerular IgG2a deposits and immunocyte infiltration (CD11b+ and CD11c+ ) at 33 wk.
Baccala, R., Gonzalez-Quintial, R., Schreiber, R. D., Lawson, B. R., Kono, D. H., & Theofilopoulos, A. N. (2012). Anti–IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice. The Journal of Immunology, 189(12), 5976-5984.
Specifications
- Host Species
- Human
- Derivation
- Humanized (mouse/human)
- Type
- Humanized (mouse/human) IgG
- Specificity
- Human IFNAR1
- Species Reactivity
- Human, Monkey
- Clone
- H2K1
- Applications
- FC, IHC, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IFNAR1 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone H2K1"
See other products for "IFNAR1"
Select a product category from the dropdown menu below to view related products.
Please select product type
ScFv Antibody Products
Mouse Antibody Products
Humanized Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
Fab Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-228 | Human Anti-IFNAR1 Recombinant Antibody (clone MEDI546); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| HPAB-M0362-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L8C3); scFv Fragment | ELISA | Human scFv |
| HPAB-M0363-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H19B7+L8C3); scFv Fragment | ELISA | Human scFv |
| HPAB-M0364-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L16C11); scFv Fragment | ELISA | Human scFv |
| HPAB-M0365-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H19B7+L16C11); scFv Fragment | ELISA | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-J0127-YC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
-1.jpg)
Application: ELISA, WB, FC, IHC, IP
Application: Neut, ELISA, WB, SPR, IF, EM
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
