Rabbit Anti-IL1RAP Antibody (VS-0924-YC46) - Cancer Stem Cell Marker (CAT#: VS-0924-YC46)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human IL1RAP

• Species Reactivity
• Human

• Applications
• IHC

• Related Disease
• Autoinflammatory diseases

• Clonality
• Polyclonal

• Purification
• Affinity purified using the PrEST antigen as affinity ligand

• Concentration
• 0.1 mg/mL

• Buffer
• PBS, pH 7.2, with 40% glycerol

• Preservative
• 0.02% Sodium azide

• Storage
• Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Immunohistochemistry (IHC): 1/50-1/200

• Alternative Names
• C3orf13; IL-1RAcP; IL1R3

• Gene ID
• 3556

• UniProt ID
• Q9NPH3

• Long Name
• Interleukin 1 receptor accessory protein

• Sequence Similarities
• Belongs to the interleukin-1 receptor family.

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn57, Asn107, Asn111, Asn118, Asn196, Asn209, and Asn299 (NX_Q9NPH3 [NX_Q9NPH3-1])
  Modification sites at PhosphoSitePlus (Q9NPH3)
  Glycosylation from GlyConnect IL1AP_HUMAN (1425)
  Glycosylation from GlyGen (Q9NPH3) 9 sites, 13 N-linked glycans (3 sites)

• Protein Refseq
• XP_016861837.1; XP_047304037.1; XP_047304038.1; XP_047304039.1; XP_047304040.1

• Function
• The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
  May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (Probable).

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

• MOB-0264MC
• Goat Anti-Rabbit IgG Antibody (HRP)

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