Recombinant Human Anti-human IL1RAP Antibody
CAT#: MHH-559
Recombinant Human Antibody raises against Human IL1RAP, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL1RAP mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IL1RAP mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/372_B3_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Peripheral nerve/ganglion
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196083-IL1RAP
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Specifications
- Immunogen
- Human interleukin 1 receptor accessory protein
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human interleukin 1 receptor accessory protein
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Western blot; Enzyme-linked Immunosorbent Assay; Immunohistochemistry; Functional Study
Product Property
- Purity
- 95% by HPLC
- Storage
- 4°C, -20°C if preferred
Target
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Related Diseases
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "IL1RAP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-559-F(E) | Recombinant Anti-human IL1RAP Antibody Fab Fragment | IF, ELISA, FuncS | Fab |
| HPAB-M0112-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0112-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0113-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0113-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0114-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0114-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0115-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0115-YC-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-559-S(P) | Recombinant Human Anti-human IL1RAP Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| HPAB-M0109-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0109-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0110-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0110-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0111-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0111-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0112-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0112-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0380CL-S(P) | Anti-Human IL1RAP Recombinant Antibody scFv Fragment (1F5) | ELISA, FC | |
| TAB-0381CL-S(P) | Anti-Human IL1RAP Recombinant Antibody scFv Fragment | ELISA, FC, FuncS | |
| TAB-0382CL-S(P) | Anti-Human IL1RAP Recombinant Antibody scFv Fragment (4B6) | ELISA, FC | |
| TAB-0380CL-F(E) | Anti-Human IL1RAP Recombinant Antibody Fab Fragment (1F5) | ELISA, FC | |
| TAB-221CT | Mouse Anti-IL1RAP Recombinant Antibody (TAB-221CT) | FC, ELISA | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0109-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0109-YC) | ELISA | Humanized IgG |
| HPAB-M0110-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0110-YC) | ELISA | Humanized IgG |
| HPAB-M0111-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0111-YC) | ELISA | Humanized IgG |
| HPAB-M0112-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0112-YC) | ELISA | Humanized IgG |
| HPAB-M0113-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0113-YC) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC46 | Rabbit Anti-IL1RAP Antibody (VS-0924-YC46) - Cancer Stem Cell Marker | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY109 | Mouse Anti-IL1RAP (clone 4B6) scFv-Fc Chimera | ELISA, FC | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC206 | Recombinant Anti-IL1RAP Vesicular Antibody, EV Displayed (VS-0425-YC206) | ELISA, FC, Cell-uptake |
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