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Human Anti-IL20 Recombinant Antibody (clone 15D2); scFv Fragment (CAT#: HPAB-0723-CN-S(P))

This is an anti-human IL20 monoclonal antibody that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes. 15D2 inhibited cynomolgus IL20-induced as well as mouse IL20-induced proliferation of the BaF-3(hIL20R) cells, while hIL19 or hIL24-induced proliferation of BaF-3(hIL20R) was not inhibited by 15D2.


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Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 IHC staining of human stomach
Figure 1 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_B_7_5.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25802/57430_A_7_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (SiHa)
Figure 6 RNA cell line category: Cell line enhanced (SiHa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162891-IL20

Specifications

  • Immunogen
  • Human IL-20
  • Host Species
  • Human
  • Type
  • Human scFv
  • Specificity
  • Human IL20
  • Species Reactivity
  • Human, Cynomolgus, Mouse
  • Clone
  • 15D2
  • Applications
  • WB, ELISA, Neut
  • Related Disease
  • Autoimmune, Inflammatory diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Interleukin 20

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 15D2"

See other products for "IL20"

Human Antibody

CAT Product Name Application Type
TAB-H34 Anti-Human IL20 Recombinant Antibody (Fletikumab) IF, IP, Neut, FuncS, ELISA, FC, ICC IgG4 - kappa
TAB-561LC-F(E) Anti-human IL20 Fab Fragment (20A10) ELISA Human antibody
TAB-562LC-F(E) Anti-human IL20 Fab Fragment (2A11) ELISA Human antibody
TAB-563LC-F(E) Anti-human IL20 Fab Fragment (7D1) ELISA Human antibody
TAB-564LC-F(E) Anti-human IL20 Fab Fragment (6E11) ELISA Human antibody

Humanized Antibody

CAT Product Name Application Type
TAB-0009CL Human Anti-IL20 Recombinant Antibody (TAB-0009CL) Inhib, IB, FC, RIA Humanized Antibody
TAB-0009CL-S(P) Human Anti-IL20 Recombinant Antibody; scFv Fragment (TAB-0009CL-S(P)) Inhib, ELISA, SPR Humanized scFv
TAB-0009CL-F(E) Human Anti-IL20 Recombinant Antibody; Fab Fragment (TAB-0009CL-F(E)) Inhib, ELISA, SPR Humanized Fab
TAB-565LC Anti-human IL20 Recombinant Antibody (FLB5M5) (TAB-565LC) ELISA, Inhib, FuncS Humanized antibody
TAB-565LC-S(P) Anti-human IL20 scFv Fragment (FLB5M5) ELISA Humanized antibody

Mouse Antibody

CAT Product Name Application Type
TAB-560LC Rat Anti-IL20 Recombinant Antibody (TAB-560LC) ELISA Rat IgG
TAB-560LC-S(P) Rat Anti-IL20 Recombinant Antibody; scFv Fragment (TAB-560LC-S(P)) ELISA Rat scFv
TAB-560LC-F(E) Rat Anti-IL20 Recombinant Antibody; Fab Fragment (TAB-560LC-F(E)) ELISA Rat Fab

Recombinant Antibody

CAT Product Name Application Type
MOB-0963CT Recombinant Mouse anti-Human IL20 Monoclonal antibody (EML1475) WB
HPAB-0008-LS Human Anti-IL20 Recombinant Antibody (HPAB-0008-LS) Inhib Humanized lgG
HPAB-0009-LS Human Anti-IL20 Recombinant Antibody (HPAB-0009-LS) Inhib Humanized lgG
HPAB-0723-CN Human Anti-IL20 Recombinant Antibody (clone 15D2) WB, ELISA, FC, IHC Human IgG4, κ
HPAB-0724-CN Human Anti-IL20 Recombinant Antibody (clone 5B7) WB, FC, IHC Human IgG4, κ

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1324CQ Rat Anti-Il20 Recombinant Antibody (clone CBL626) Neut Rat IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4256 Rabbit Anti-IL20 Recombinant Antibody (clone SI336DS) ELISA Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0008-LS-F(E) Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0008-LS-F(E)) Inhib Humanized Fab
HPAB-0009-LS-F(E) Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0009-LS-F(E)) Inhib Humanized Fab
HPAB-0723-CN-F(E) Human Anti-IL20 Recombinant Antibody (clone 15D2); Fab Fragment WB, ELISA, Neut Human Fab
HPAB-0724-CN-F(E) Human Anti-IL20 Recombinant Antibody (clone 5B7); Fab Fragment WB, ELISA, Neut Human Fab
HPAB-0069-WJ-F(E) Human Anti-IL20 Recombinant Antibody; Fab Fragment (HPAB-0069-WJ-F(E)) IHC, ELISA, WB Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0008-LS-S(P) Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0008-LS-S(P)) Inhib Humanized scFv
HPAB-0009-LS-S(P) Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0009-LS-S(P)) Inhib Humanized scFv
HPAB-0724-CN-S(P) Human Anti-IL20 Recombinant Antibody (clone 5B7); scFv Fragment WB, ELISA, Neut Human scFv
HPAB-0069-WJ-S(P) Human Anti-IL20 Recombinant Antibody; scFv Fragment (HPAB-0069-WJ-S(P)) IHC, ELISA, WB Human scFv

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H34 Afuco™ Anti-IL20 ADCC Recombinant Antibody (Fletikumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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