Human Anti-IL20 Recombinant Antibody (clone 5B7) (CAT#: HPAB-0724-CN)
This is an anti-human IL20 monoclonal antibody that can reduce IL20 mediated activation of both IL20R1/IL20R2 and IL22R1/IL20R2 receptor complexes. The antibody 5B7 can be used for treating various diseases and disorders, including autoimmune or inflammatory diseases or disorders.
Specific Inquiry
WB
Figure 1 Anti-IL-20 mAb 7E improved motor function and sensory function in SCI rats.
Data from one representative experiment of three independent experiments is shown.
Lee, J. S., Hsu, Y. H., Chiu, Y. S., Jou, I. M., & Chang, M. S. (2020). Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. Journal of Neuroinflammation, 17, 1-12.
IHC
Figure 2 IL-20 promoted astrocyte activation in HA cell line.
Data are expressed as mean ± SD and are representative of three independent experiments performed in triplicate.
Lee, J. S., Hsu, Y. H., Chiu, Y. S., Jou, I. M., & Chang, M. S. (2020). Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. Journal of Neuroinflammation, 17, 1-12.
Specifications
- Immunogen
- Human IL-20
- Host Species
- Human
- Type
- Human IgG4, κ
- Specificity
- Human IL20
- Species Reactivity
- Human, Cynomolgus, Mouse
- Clone
- 5B7
- Applications
- WB, FC, IHC
- Related Disease
- Autoimmune, Inflammatory diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL20 antibody has been reported in applications of Western Blot, Immunohistochemistry, Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0009CL | Human Anti-IL20 Recombinant Antibody (TAB-0009CL) | Inhib, IB, FC, RIA | Humanized Antibody |
| TAB-0009CL-S(P) | Human Anti-IL20 Recombinant Antibody; scFv Fragment (TAB-0009CL-S(P)) | Inhib, ELISA, SPR | Humanized scFv |
| TAB-0009CL-F(E) | Human Anti-IL20 Recombinant Antibody; Fab Fragment (TAB-0009CL-F(E)) | Inhib, ELISA, SPR | Humanized Fab |
| TAB-565LC | Anti-human IL20 Recombinant Antibody (TAB-565LC) | ELISA, Inhib, FuncS | Humanized antibody |
| TAB-565LC-S(P) | Anti-human IL20 scFv Fragment (TAB-565LC-S(P)) | ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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