Human Anti-IL6R Recombinant Antibody (clone F2) (CAT#: HPAB-AP721-YC)
Provided are antibodies to IL-6 receptor, which can be used for the prevention and treatment of autoimmune diseases. The antibody is suitable for ELISA, Inhibitation, and functional assay.
Specific Inquiry
ELISA
Figure 1 Generation of the dual target-directed antibody (DTA) against IL-6R and TNFα.
Binding affinities of anti-IL-6R antibody candidates (A7, B10, D2 and F2) to IL-6R. The values of dissociation constant (Kd) and coefficient of determination (R²) are displayed under the graph.
Kim, Y., Yi, H., Jung, H., Rim, Y. A., Park, N., Kim, J., ... & Ju, J. H. (2016). A dual target-directed agent against interleukin-6 receptor and tumor necrosis factor α ameliorates experimental arthritis. Scientific reports, 6(1), 1-12.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human IL6R
- Species Reactivity
- Human
- Clone
- F2
- Applications
- ELISA, Inhib, FuncS
- Related Disease
- Autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL6R antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition, Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1237z | Mouse Anti-IL6R Recombinant Antibody (clone 23B11) | ICC, IF, IHC, FC, IP, ELISA | Mouse IgG1 |
| HPAB-0034-WJ | Mouse Anti-IL6R Recombinant Antibody (clone 8C1D8B5) | ELISA, WB | Mouse IgG1 |
| HPAB-1761LY | Mouse Anti-IL6R Recombinant Antibody (clone G10) | FC | Mouse IgG |
| HPAB-0612-WJ | Mouse Anti-IL6R Recombinant Antibody (HPAB-0612-WJ) | ELISA, FC | Mouse IgG1 |
| HPAB-AP718-YC | Human Anti-IL6R Recombinant Antibody (clone A7) | ELISA, Inhib, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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