Mouse Anti-ITGA4 Recombinant Antibody (clone HP2/1) (CAT#: HPAB-0083-YJ)
This product is a mouse antibody that recognizes human alpha4 integrin also known as CD49d, integrin alpha-4 or VLA-4 subunit alpha. Mab HP2/1 is cross-reactive with alpha4 integrin of Human, Rat, Rhesus Monkey, Bovine, Pig, Cynomolgus monkey, Goat, Rabbit, Llama, Horse, Mink, Mustelid, Cat. Mab HP2/1 can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure and has been demonstrated to inhibit cell binding to soluble VCAM-1. Mab HP2/1 can also be used in the treatment of Nephritis.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (fHDF/TERT166, HEL, JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
Specifications
- Immunogen
- JM leukaemia line.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human
- Species Reactivity
- Human, Rat, Rhesus Monkey, Bovine, Pig, Cynomolgus monkey, Goat, Rabbit, Llama, Horse, Mink, Mustelid, Cat
- Clone
- HP2/1
- Applications
- FC, FuncS, IHC-Fr, IP
- Related Disease
- Nephritis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IA4; CD49D; 269C wild type; CD49 antigen-like family member D; VLA-4 subunit alpha; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; HP2/1
- Gene ID
- 3676
- UniProt ID
- P13612
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ITGA4"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Immunotoxin Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Human Antibody Products
Mouse Antibody Products
Blocking Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-135 | Anti-Human Integrin alpha 4 beta 7 Recombinant Antibody (Etrolizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0083-YJ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IHC
Application: Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FC, Inhib
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
