1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Mouse Anti-MDM2 Recombinant Antibody (VS13-YC717) (CAT#: VS13-YC717)

    The Mouse Anti-MDM2 Recombinant Antibody is specific for human and monkey MDM2. MDM2 encodes an E3 ubiquitin ligase, promoting tumor formation by targeting tumor suppressors for degradation, like p53. It's involved in various cancers, with amplification or overexpression observed, featuring multiple tumor-specific splice variants. The anti-MDM2 antibody can be used for Western blot (1/1000), Immunofluorescence of cells (1/500), Immunohistochemistry-paraffin (1/1000).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16303/if_selected.jpg
    Figure 2 IF staining of human cell line U-2 OS
    Figure 2 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/79977/1999_F7_3_selected.jpg
    Figure 3 IHC staining of human cerebellum
    Figure 3 IHC staining of human cerebellum
    (Immunohistochemical staining of human cerebellum shows strong nuclear positivity.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/ihc_selected.jpg
    Figure 4 IHC staining of human ovary
    Figure 4 IHC staining of human ovary
    (Immunohistochemical staining of human ovary shows strong nuclear positivity in ovarian stroma cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16303/37938_A_6_7_selected.jpg
    Figure 5 IHC staining of human placenta
    Figure 5 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong nuclear and cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/79977/170698_A_2_7_selected.jpg
    Normal Tissue
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_B_8_5.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_9_3.jpg
    Figure 8 Liver
    Figure 8 Liver
    (Cholangiocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Hepatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_8_4.jpg
    Figure 9 Pancreas
    Figure 9 Pancreas
    (Exocrine glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Pancreatic endocrine cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_2_3.jpg
    Figure 10 Kidney
    Figure 10 Kidney
    (Cells in glomeruli
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_8_5.jpg
    Figure 11 Testis
    Figure 11 Testis
    (Pachytene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Peritubular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Round or early spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_5_6.jpg
    Figure 12 Lymph node
    Figure 12 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/86/33293_A_9_8.jpg
    RNA Expression
    Figure 13 RNA cell line category: Cell line enhanced (HBEC3-KT, U-698)
    Figure 13 RNA cell line category: Cell line enhanced (HBEC3-KT, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135679-MDM2

    Specifications

    • Immunogen
    • Recombinant human MDM2, aa 1-491.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human and Monkey MDM2
    • Species Reactivity
    • Human, Monkey
    • Applications
    • WB, IHC-P, ICC, IF
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Affinity Chromatography purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS (pH 7.4) containing 40% Glycerol and 0.1% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/1000
      Immunofluorescence (IF-cell): 1/500
      Immunohistochemistry-paraffin (IHC-P): 1/1000

    Target

    • Alternative Names
    • MDM2 Proto-Oncogene; MDM2 Proto-Oncogene, E3 Ubiquitin Protein Ligase; Oncoprotein Mdm2; Hdm2; Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein (Mouse); Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein; Mouse Double Minute 2, Human Homolog Of; P53-Binding Protein; Double Minute 2, Human Homolog Of; P53-Binding Protein; Mdm2, P53 E3 Ubiquitin Protein Ligase Homolog; MDM2 Oncogene, E3 Ubiquitin Protein Ligase;
    • Long Name
    • MDM2 Proto-Oncogene
    • Cellular Localization
    • Nucleus; Nucleoplasm; Nucleolus; Cytoplasm

    Recommended Products

    Secondary Antibody

    Isotype Control

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "MDM2"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Fab Antibody Products ScFv Antibody Products Chicken IgY Antibody Products Rabbit Monoclonal Antibody Products MHC Tetramer Products for Cancer
    CAT Product Name Application Type
    MOB-648 Recombinant Anti-human MDM2 Antibody ELISA, WB, IF, FuncS IgG
    VS3-XY1056 Mouse Anti-MDM2 Recombinant Antibody (clone 3G2) WB, IP, IF, IHC Mouse IgG1
    VS3-FY917 Recombinant Mouse Anti-MDM2 Antibody (clone 3C1E3) ELISA, IHC, FC Mouse IgG2b
    VS3-FY918 Recombinant Mouse Anti-MDM2 Antibody (clone 4A8D12) ELISA, FC Mouse IgG1
    VS3-FY919 Recombinant Rabbit Anti-MDM2 (phospho Ser166) Antibody (clone R08-8C7) WB, IHC-P Rabbit IgG

    Customer Reviews and Q&As

    Submit a review or a question

    There are currently no Customer reviews or questions for VS13-YC717. Click the button above to contact us or submit your feedback about this product.

    Popular products with customers

    Figure 3 Anti-Human IL17RA Antibody (TAB-134) in DB

    Human Anti-IL17RA Recombinant Antibody (TAB-134) (CAT# TAB-134)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 5 Anti-Human IL5RA Antibody (TAB-222) in DB

    Anti-Human IL5RA Recombinant Antibody (TAB-222) (CAT# TAB-222)
    Application: WB, FC, IP, ELISA, Neut, FuncS, IF

    Figure 2 Anti-Human IL23 Antibody (TAB-875) in HPLC

    Anti-Human IL23 Recombinant Antibody (Tildrakizumab) (CAT# TAB-875)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 10 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-770) resulted in an increase of IFN-γ production.

    Anti-PDCD1 Recombinant Antibody (TAB-770) (CAT# TAB-770)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 1 Anti-Human IL5 Recombinant Antibody (TAB-031) in SDS-PAGE

    Anti-Human IL5 Recombinant Antibody (TAB-031) (CAT# TAB-031)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 3 Anti-Human EGFR Antibody (TAB-003) in DB

    Anti-Human EGFR Recombinant Antibody (Cetuximab) (CAT# TAB-003)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 4 Anti-Human EPCAM Recombinant Antibody (TAB-235CL) in ELISA

    Human Anti-Human EPCAM Recombinant Antibody (3622W94) (CAT# TAB-235CL)
    Application: Cyt, FC

    Figure 2 Human IL31 Recombinant Antibody (AFC-409CL) in ELISA

    Afuco™ Anti-Human IL31 ADCC Recombinant Antibody (BMS-981164), ADCC Enhanced (CAT# AFC-409CL)
    Application:

    Figure 5 Recombinant Human Anti-IAV HA Antibody (5J8) (PABL-207) in Dot Blot

    Recombinant Human Anti-IAV HA Antibody (5J8) (CAT# PABL-207)
    Application: FuncS

    Figure 2 Anti-PF4 Recombinant Antibody (PABL-299) in HPLC

    Mouse Anti-PF4 Recombinant Antibody (clone KKO) (CAT# PABL-299)
    Application: ELISA, FuncS

    Figure 5 Human Anti-IL13 Recombinant Antibody (clone CNTO607) (PABW-170) in SEC-HPLC

    Human Anti-IL13 Recombinant Antibody (clone CNTO607) (CAT# PABW-170)
    Application: ELISA, WB, Neut

    Figure 2 Human Anti-CD3 Recombinant Antibody (TAB-0416CL-S(P)) in WB

    Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (CAT# TAB-0416CL-S(P))
    Application: IB, ELISA, FC, FuncS

    Figure 3 Anti-Human PDCD1 Recombinant Antibody Fab Fragment (PD1-17), gggc tag (TAB-0961CL-F(E)) in DB

    Anti-Human PDCD1 Recombinant Antibody Fab Fragment (PD1-17) (CAT# TAB-0961CL-F(E))
    Application: ELISA

    Figure 2 Anti-Human CD47 Recombinant Antibody (TAB-303LC) in ELISA

    Human Anti-CD47 Recombinant Antibody (TAB-303LC) (CAT# TAB-303LC)
    Application: ELISA

    Figure 1 Mouse Anti-Collagen I (RGD motif) Recombinant Antibody (TAB-053MZ) in SDS-PAGE

    Mouse Anti-Collagen I (RGD motif) Recombinant Antibody (TAB-053MZ) (CAT# TAB-053MZ)
    Application: WB, IF, FuncS

    Figure 2 Anti-Human FAP Antibody (TAB-024WM) in ELISA

    Human Anti-FAP Recombinant Antibody (TAB-024WM) (CAT# TAB-024WM)
    Application: IHC, ELISA, FC, IF

    Figure 2 Anti-Human TREM1 Recombinant Antibody (TAB-167CQ) in SDS-PAGE

    Human Anti-TREM1 Recombinant Antibody (TAB-167CQ) (CAT# TAB-167CQ)
    Application: ELISA, FC, WB, Block

    Figure 3 Anti-RABV G Recombinant Antibody (MRO-730LC) in WB

    Anti-RABV G Recombinant Antibody (MRO-730LC) (CAT# MRO-730LC)
    Application: ELISA, Neut, WB

    Figure 4 Mouse Anti-EGFR Recombinant Antibody (HPAB-0727-CN) in WB

    Mouse Anti-EGFR Recombinant Antibody (clone EGFR) (CAT# HPAB-0727-CN)
    Application: ELISA, FC, IHC, Neut

    Figure 1 Mouse Anti-MPO Recombinant Antibody (MOB-0130F) in IHC

    Mouse Anti-MPO Recombinant Antibody (MOB-0130F) (CAT# MOB-0130F)
    Application: IHC-P, IF

    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare