Recombinant monoclonal antibody specially binds to myelin oligodendrocyte glycoprotein (MOG). This monkey anti-MOG antibody (M3-24) can be useful to study autoreactive humoral immune responses against central nervous system (CNS) myelin antigens in multiple sclerosis (MS).
Figure 1 Brain and cerebellum nonhuman primate myelin staining with commercial monoclonal MOG.
Purified IgG-AF594 from patients colocalized with commercial anti-MBP.
Cobo-Calvo, A., Ayrignac, X., Kerschen, P., Horellou, P., Cotton, F., Labauge, P., ... & Marignier, R. (2019). Cranial nerve involvement in patients with MOG antibody–associated disease. Neurology-Neuroimmunology Neuroinflammation, 6(2).
Figure 2 Comparison of sensitivity between avidin-biotin ELISA (filled circles) and conventional ELISA (open circles) for detection of IgG in human normal sera.
Arrows indicate mean amount of IgG detected when the OD at 405 nm is 0.1.
Lackner, P., Kuenz, B., Reindl, M., Morandell, M., Berger, T., Schmutzhard, E., & Eggers, C. (2010). Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study. Journal of neuroinflammation, 7(1), 79.
Figure 3 Specific staining of anti-MOG IgG antibodies by Western blot.
Arrows indicate immunostaining bands.
Lackner, P., Kuenz, B., Reindl, M., Morandell, M., Berger, T., Schmutzhard, E., & Eggers, C. (2010). Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study. Journal of neuroinflammation, 7(1), 79.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-670 | Recombinant Anti-human MOG Antibody | WB, FC, FuncS | IgG |
FAMAB-1469CQ | Human Anti-MOG Recombinant Antibody (clone M45) | ELISA | Human IgG1 |
FAMAB-1470CQ | Human Anti-MOG Recombinant Antibody (clone M3-24) | ELISA | Human IgG1 |
FAMAB-1471CQ | Human Anti-MOG Recombinant Antibody (clone M38) | ELISA | Human IgG1 |
FAMAB-1472CQ | Human Anti-MOG Recombinant Antibody (clone M3-31) | ELISA | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-670-F(E) | Recombinant Anti-human MOG Antibody Fab Fragment | Neut, IF, FuncS | Fab |
MHH-670-F(E) | Recombinant Human Anti-human MOG Antibody Fab Fragment | WB, Dot, FuncS | Fab |
HPAB-1774-FY-S(P) | Human Anti-MOG Recombinant Antibody (clone AB138); Fab Fragment | Neut | Chimeric (marmoset/human) Fab |
FAMAB-0228JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M12E); Fab Fragment | ELISA, FuncS | Monkey Fab |
FAMAB-0229JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); Fab Fragment | ELISA, FuncS | Monkey Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-670-S(P) | Recombinant Anti-human MOG Antibody scFv Fragment | Neut, WB, FuncS | scFv |
HPAB-1774-FY-F(E) | Monkey Anti-MOG Recombinant Antibody (clone AB138); scFv Fragment | Neut | Mouse scFv |
FAMAB-0006WJ-S(P) | Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5); scFv Fragment | ELISA | Chimeric (mouse/human) scFv |
FAMAB-0228JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M12E); scFv Fragment | ELISA, FuncS | Monkey scFv |
FAMAB-0229JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); scFv Fragment | ELISA, FuncS | Monkey scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC661 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, APC | FC | |
MHC-LC702 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, PE | FC | |
MHC-LC926 | IAb/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Monomer | MHC Multimer | |
MHC-YF1586 | BV421-H-2 IAb/Mouse MOG (GWYRSPFSRVVH) MHC Tetramer | FC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2266 | Hi-Affi™ Recombinant Rabbit Anti-MOG Monoclonal Antibody (DS2266AB) | WB, IHC, ICC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1988 | PE-DRB1*15:01/Human MOG (MEVGWYRPPFSRVVHLYRNGK) MHC Tetramer | FCM | |
MHC-CN0317 | APC-H-2Db/Human MOG (VGWYRSPFSRVVHL) MHC Tetramer | FCM | |
MHC-CN1422 | PE-I-Ab/Human MOG (GWYRSPFSRVVH) MHC Tetramer | FCM | |
MHC-YF305 | IAb/Human MOG (GWYRSPFSRVVH) MHC Monomer | MHC Multimer | |
MHC-YF307 | IAb/Human MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Monomer | MHC Multimer |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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