Monkey Anti-MOG Recombinant Antibody (clone M3-24)
CAT#: FAMAB-0229JF
Recombinant monoclonal antibody specially binds to myelin oligodendrocyte glycoprotein (MOG). This monkey anti-MOG antibody (M3-24) can be useful to study autoreactive humoral immune responses against central nervous system (CNS) myelin antigens in multiple sclerosis (MS).
Published Data
Gene Expression
ELISA
Figure 2 Comparison of sensitivity between avidin-biotin ELISA (filled circles) and conventional ELISA (open circles) for detection of IgG in human normal sera.
Arrows indicate mean amount of IgG detected when the OD at 405 nm is 0.1.
Lackner, P., Kuenz, B., Reindl, M., Morandell, M., Berger, T., Schmutzhard, E., & Eggers, C. (2010). Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study. Journal of neuroinflammation, 7(1), 79.
WB
Figure 3 Specific staining of anti-MOG IgG antibodies by Western blot.
Arrows indicate immunostaining bands.
Lackner, P., Kuenz, B., Reindl, M., Morandell, M., Berger, T., Schmutzhard, E., & Eggers, C. (2010). Antibodies to myelin oligodendrocyte glycoprotein in HIV-1 associated neurocognitive disorder: a cross-sectional cohort study. Journal of neuroinflammation, 7(1), 79.
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Normal Tissue
Figure 1 IHC staining of human cerebral cortex
High expression. RNA expression: 73.8 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Low expression. RNA expression: 0.0 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Colon
Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_9_3.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21873/51773_A_4_6.jpg
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Specifications
- Immunogen
- Recombinant protein corresponding to the extracellular domain of rat MOGaa1-125
- Host Species
- Monkey
- Derivation
- C. jacchus marmosets phage display Fab library
- Type
- Monkey Fab
- Specificity
- Rat MOG
- Species Reactivity
- Rat
- Clone
- M3-24
- Applications
- WB, ELISA, IHC
- Related Disease
- Multiple sclerosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The MOG antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
- Alternative Names
- MOG; myelin oligodendrocyte glycoprotein
- Gene ID
- 24558
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670-F(E) | Recombinant Anti-human MOG Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| PFBZ-152 | Mouse Anti-MOG Recombinant Antibody (clone 8-18C5); Fab Fragment | WB | Mouse Fab |
| FAMAB-0006WJ-F(E) | Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
| FAMAB-0228JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M12E); Fab Fragment | ELISA, FuncS | Monkey Fab |
| FAMAB-0229JF-F(E) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); Fab Fragment | ELISA, FuncS | Monkey Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-670-S(P) | Recombinant Anti-human MOG Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| HPAB-1774-FY-F(E) | Monkey Anti-MOG Recombinant Antibody (clone AB138); scFv Fragment | Neut | Mouse scFv |
| FAMAB-0006WJ-S(P) | Chimeric (mouse/human) Anti-MOG Recombinant Antibody (clone h8-18C5); scFv Fragment | ELISA | Chimeric (mouse/human) scFv |
| FAMAB-0228JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M12E); scFv Fragment | ELISA, FuncS | Monkey scFv |
| FAMAB-0229JF-S(P) | Monkey Anti-MOG Recombinant Antibody (clone M3-24); scFv Fragment | ELISA, FuncS | Monkey scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC661 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, APC | FC | |
| MHC-LC702 | I-Ab/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Tetramer, PE | FC | |
| MHC-LC926 | IAb/Mouse MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Monomer | MHC Multimer | |
| MHC-YF1586 | BV421-H-2 IAb/Mouse MOG (GWYRSPFSRVVH) MHC Tetramer | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2266 | Hi-Affi™ Recombinant Rabbit Anti-MOG Monoclonal Antibody (DS2266AB) | WB, IHC, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1988 | PE-DRB1*15:01/Human MOG (MEVGWYRPPFSRVVHLYRNGK) MHC Tetramer | FCM | |
| MHC-CN0317 | APC-H-2Db/Human MOG (VGWYRSPFSRVVHL) MHC Tetramer | FCM | |
| MHC-CN1422 | PE-I-Ab/Human MOG (GWYRSPFSRVVH) MHC Tetramer | FCM | |
| MHC-YF305 | IAb/Human MOG (GWYRSPFSRVVH) MHC Monomer | MHC Multimer | |
| MHC-YF307 | IAb/Human MOG (MEVGWYRSPFSRVVHLYRNGK) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1470CQ | Human Anti-MOG Recombinant Antibody (clone M3-24) | ELISA | Human IgG1 |
| FAMAB-1471CQ | Human Anti-MOG Recombinant Antibody (clone M38) | ELISA | Human IgG1 |
| FAMAB-1472CQ | Human Anti-MOG Recombinant Antibody (clone M3-31) | ELISA | Human IgG1 |
| FAMAB-1473CQ | Human Anti-MOG Recombinant Antibody (clone M3-8) | ELISA | Human IgG1 |
| FAMAB-1474CQ | Human Anti-MOG Recombinant Antibody (clone M26) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC900 | AbPlus™ Anti-Mog Magnetic Beads (VS-0724-YC900) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY157 | Human Anti-MOG (clone h8-18C5) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC509 | Recombinant Anti-MOG Vesicular Antibody, EV Displayed (VS-0425-YC509) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4469 | Anti-Mouse MOG Immunohistochemistry Kit | IHC | |
| VS-0525-XY4470 | Anti-Rat MOG Immunohistochemistry Kit | IHC |
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