Mouse Anti-TNFRSF10B Recombinant Antibody (clone 2H5B8)

Name: Mouse Anti-TNFRSF10B Recombinant Antibody (clone 2H5B8)
SKU: VS7-0425-WR1010
Rating: 5 (1 reviews)

CAT#: VS7-0425-WR1010

This product is a mouse IgG1 antibody that binds to human TNFRSF10B. The antibody 2H5B8 recognizes specific amino acid domain of human TNFRSF10B (AA: extra 56-210). It can be used for WB and ELISA assays.

Gene Expression

Normal Tissue Figure 1 Cerebral cortex

Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

Neuropil
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51170_B_7_5.jpg

Normal Tissue Figure 2 Colon

Endothelial cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_3.jpg

Normal Tissue Figure 3 Liver

Cholangiocytes
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_4.jpg

Normal Tissue Figure 4 Kidney

Cells in glomeruli
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_8_5.jpg

Normal Tissue Figure 5 Testis

Cells in seminiferous ducts
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_6_6.jpg

Normal Tissue Figure 6 Lymph node

Non-germinal center cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_8.jpg

RNA Expression Figure 7 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

RNA Expression Figure 7 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B

❮

❯

Specifications

Immunogen
Recombinant human TNFRSF10B (AA: extra 56-210) fragment expressed in E. Coli.

Host Species
Mouse

Type
Mouse IgG1

Specificity
Human TNFRSF10B

Species Reactivity
Human

Clone
2H5B8

Molecule Class
TNF-Receptor

Applications
WB, ELISA

Conjugate
Unconjugated

Related Disease
Squamous cell carcinoma of the head and neck (HNSCC)

Product Property

Clonality
Monoclonal

Purity
>95% as determined by SDS-PAGE and SEC-HPLC analysis

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
0.05% sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Ice packs

Applications

Application Notes
Western Blot: 1:500 - 1:2000
Enzyme-linked Immunosorbent Assay: 1:10000

Target

Alternative Names
Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; D

Gene ID
8795

UniProt ID
O14763

Long Name
TNF receptor superfamily member 10b

Cellular Localization
Membrane

Post Translation Modifications
Disulfide bond; Glycoprotein

Protein Refseq
NP_003833.4

Function
Receptor

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS7-0425-WR1010.pdf

MSDS

MSDS - VS7-0425-WR1010.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Secondary Antibody

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Reconstitution Buffer

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Recommended Dilution Buffer

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