This product is a recombinant antibody that recognizes TNFRSF8. The monoclonal antibody 5F11 reacts with the epitope of TNFRSF8.
Figure 1 Shows a graph comparing dose dependent binding of anti-CD30 HuMabs, 17G1, 5F11, 2H9 and an isotype control to recombinant CD30.
Figure 2 Shows a graph comparing dose dependent binding of anti-CD30 HuMabs, 17G 1, 5F11, 2H9 and an isotype control to the Hodgkin's lymphoma cell line, L540.
Figure 3 Shows a graph comparing mononuclear cell-mediated antibody dependent cellular cytotoxicity of L540 Hodgkin's tumor cells by anti-CD30 HuMabs, 17G1, 5F11, 2H9 and an isotype control.
Figure 4 Shows a graph comparing monocyte-mediated antibody dependent cellular cytotoxicity of L540 Hodgkin's tumor cells by anti-CD30 HuMabs, 17G1, 5F11, 2H9 and an isotype control.
Figure 5 A graph shows the inhibition of cell growth using HuMab 5F11.
Figure 6 A graph shows the growth inhibition of CD30-expressing tumor cells by HuMab 5F11 in vivo using a xenografted mouse model.
Figure 7 A graph shows the effects of HuMab 5F11 treatment on the survival of SCID mice challenged with human HL cells L540CY in a disseminated model.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-144 | Anti-Human CD30 Recombinant Antibody (Iratumumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-153 | Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (clone Brentuximab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G062E | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G062R | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-RTA | Cytotoxicity assay, Function study | |
AGTO-G062S | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-Sap | Cytotoxicity assay, Function study | |
AGTO-L041R | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L041S | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-Sap | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-635CL | Human Anti-TNFRSF8 Recombinant Antibody (TAB-635CL) | ELISA | Human IgG |
TAB-103LC | Anti-Human TNFRSF8 Recombinant Antibody | WB, FC, ELISA | Humanized antibody |
TAB-103LC-S(P) | Anti-Human TNFRSF8 Recombinant Antibody scFv Fragment | WB, FC, ELISA | Humanized antibody |
TAB-103LC-F(E) | Anti-Human TNFRSF8 Recombinant Antibody Fab Fragment | WB, FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC-1 | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0597MZ | Chicken Anti-TNFRSF8 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2165CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone mCD30.1) | FC, Stim, Costim, Block | Hamster IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2166CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone 2SH12-5F) | Neut, FC | Hamster IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3617 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3617AB) | WB, IHC-P | Rabbit IgG |
MOR-3618 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3618AB) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-YC-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0329-YC-F(E)) | ELISA, FC, Cyt, FuncS | Mouse Fab |
HPAB-0330-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0330-YC-F(E)) | ELISA, FC, Cyt, FuncS | Human Fab |
HPAB-0331-YC-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0331-YC-F(E)) | ELISA, FC, Cyt, FuncS | Mouse Fab |
HPAB-0332-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0332-YC-F(E)) | FC, Cyt | Human Fab |
HPAB-0333-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0333-YC-F(E)) | FC, Cyt, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0445-CN | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T105) | WB, ELISA, FC | Mouse IgG1 |
HPAB-0447-CN | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T405) | WB, ELISA | Mouse IgG2b |
HPAB-0325CQ | Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0325CQ) | ELISA, FC, FuncS, Cyt | Humanized IgG |
HPAB-0326CQ | Mouse Anti-TNFRSF8 Recombinant Antibody (clone Ki-4) | WB, IP, ELISA | Mouse IgG1, κ |
HPAB-1930-FY | Human Anti-TNFRSF8 Recombinant Antibody (clone 2H9) | ELISA, FC, ADCC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0445-CN-S(P) | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T105); scFv Fragment | WB, ELISA, FC | Mouse scFv |
HPAB-0447-CN-S(P) | Mouse Anti-TNFRSF8 Recombinant Antibody (clone T405); scFv Fragment | WB, ELISA | Mouse scFv |
HPAB-1929-FY-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone 17G1); scFv Fragment | FC, ELISA | Human scFv |
HPAB-1930-FY-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone 2H9); scFv Fragment | FC, ELISA | Human scFv |
HPAB-1931-FY-F(E) | Human Anti-TNFRSF8 Recombinant Antibody (clone 5F11); scFv Fragment | FC, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-144 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Iratumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-153 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Brentuximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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