Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0237-YJ-VHH)

Name: Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0237-YJ-VHH)
SKU: HPAB-0237-YJ-VHH
Rating: 5 (1 reviews)

CAT#: HPAB-0237-YJ-VHH

This product is a recombinant Llama single domain antibody that recognizes human TNFSF13B. The single domain antibody 52 reacts with the epitope (Extracellular domain) of TNFSF13B. It can block combination of BAFF and its three related receptors, can substantially inhibit B cell proliferation or viability and can be used for detection and /or treatment on a plurality of BAFF expression abnormity-related diseases.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line THP-1

Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1926_A6_2_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A549

Immunofluorescent staining of human cell line A549 shows localization to plasma membrane, Focal adhesion sites & Vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1702_E2_13_cr5db6ea10de8f3_blue_red_green.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to Vesicles & Focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1708_E6_34_blue_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_B_7_5.jpg

Normal Tissue Figure 5 Colon

Peripheral nerve/ganglion
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_9_3.jpg

Normal Tissue Figure 6 Kidney

Cells in tubules
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_7_5.jpg

Normal Tissue Figure 7 Testis

Cells in seminiferous ducts
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_6_6.jpg

Normal Tissue Figure 8 Lymph node

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_8_8.jpg

Normal Tissue Figure 9 Tonsil

Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Squamous epithelial cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_5_8.jpg

RNA Expression Figure 10 RNA cell line category: Cell line enriched (U-937)

Cell lines ordered by descending RNA expression order.

RNA Expression Figure 10 RNA cell line category: Cell line enriched (U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102524-TNFSF13B

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Specifications

Immunogen
Recombinant human BAFF extracellular domain

Host Species
Llama

Type
Llama VHH

Specificity
Human

Species Reactivity
Human

Clone
HPAB-0237-YJ-VHH

Applications
ELISA, Inhibition

Related Disease
BAFF expression abnormity-related diseases

Target

Alternative Names
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20; tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; epididymis secretory sperm binding protein; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4

Gene ID
10673

UniProt ID
Q9Y275

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0237-YJ-VHH.pdf

MSDS

MSDS - HPAB-0237-YJ-VHH.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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HPAB-0235-YJ-VHH	Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0235-YJ-VHH)	ELISA, Inhib	Llama VHH
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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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TAB-1180CL-S(P)	Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (TAB-1180CL-S(P))	Neut	Human scFv
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CAT	Product Name	Application	Type
TAB-1194CL	Human Anti-TNFSF13B Recombinant Antibody (TAB-1194CL)	Inhib	Humanized antibody
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CAT	Product Name	Application	Type
HPAB-0235-YC-F(E)	Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0235-YC-F(E))	ELISA, Neut	Human Fab
HPAB-0121-FY-F(E)	Mouse Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0121-FY-F(E))	ELISA	Mouse Fab
HPAB-0730LY-F(E)	Human Anti-TNFSF13B Recombinant Antibody (clone CBL016); Fab Fragment	ELISA	Human Fab
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