Recombinant Anti-TNFSF13B Vesicular Antibody, EV Displayed (VS-0425-YC601)
CAT#: VS-0425-YC601
The Recombinant Anti-TNFSF13B Vesicular Antibody, EV Displayed (VS-0425-YC601) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to TNFSF13B-expressed cells or tissues. TNFSF13B is a TNF ligand family cytokine, acting as a potent B cell activator involved in their proliferation and differentiation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1926_A6_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to plasma membrane, Focal adhesion sites & Vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1702_E2_13_cr5db6ea10de8f3_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to Vesicles & Focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/30526/1708_E6_34_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Peripheral nerve/ganglion
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_8_8.jpg
Normal Tissue
Figure 9 Tonsil
Germinal center cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Squamous epithelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9188/24697_A_5_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enriched (U-937)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 10 RNA cell line category: Cell line enriched (U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102524-TNFSF13B
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- TNFSF13B
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- TNF superfamily member 13b
- Biological Process
- Immunity
- Molecular Function
- Cytokine
- Cellular Localization
- Plasma membrane, Vesicles, Focal adhesion sites
- Introduction
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
- Alternative Names
- BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
- Gene ID
- 10673
- UniProt ID
- Q9Y275
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1226z | Mouse Anti-TNFSF13B Recombinant Antibody (clone 25D8) | WB, IP, IF, ELISA | Mouse IgM, κ |
| HPAB-1255WJ | Human Anti-B lymphocyte stimulator protein Recombinant Antibody (HPAB-1255WJ) | ELISA | Human IgG |
| HPAB-1256WJ | Human Anti-B lymphocyte stimulator protein Recombinant Antibody (HPAB-1256WJ) | ELISA | Human IgG |
| HPAB-1257WJ | Human Anti-B lymphocyte stimulator protein Recombinant Antibody (HPAB-1257WJ) | ELISA | Human IgG |
| VS7-0425-WR1026 | Mouse Anti-TNFSF13B Recombinant Antibody (clone 6C3A2) | WB, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-024 | Recombinant Anti-Human TNFSF13B VHH Single Domain Antibody | CA, IP, IF, FuncS | Llama VHH |
| TAB-0055CL-VHH | Anti-Human TNFSF13B VHH Single Domain Antibody (TAB-0055CL-VHH) | ELISA, FuncS, Inhib, BLI | Single domain antibody |
| HPAB-0235-YJ-VHH | Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0235-YJ-VHH) | ELISA, Inhib | Llama VHH |
| HPAB-0236-YJ-VHH | Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0236-YJ-VHH) | ELISA, Inhib | Llama VHH |
| HPAB-0237-YJ-VHH | Recombinant Llama Anti-TNFSF13B Single Domain Antibody (HPAB-0237-YJ-VHH) | ELISA, Inhib | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-216 | Anti-Human BAFF Recombinant Antibody (TAB-216) | FuncS, IF, Neut, ELISA, FC, IP, IHC | IgG4 - kappa |
| TAB-1158CL | Anti-Human TNFSF13B Recombinant Antibody (6C10) | ELISA, Inhib | Fully human antibody |
| TAB-1159CL | Anti-Human TNFSF13B Recombinant Antibody (10C11) | ELISA, Inhib | Fully human antibody |
| TAB-1160CL | Anti-Human TNFSF13B Recombinant Antibody (6A11) | ELISA | Fully human antibody |
| TAB-1161CL | Anti-Human TNFSF13B Recombinant Antibody (5B7) | ELISA, Inhib | Fully human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1179CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1179CL) | Neut | Chimeric (Mouse/Human) antibody |
| TAB-1180CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1180CL) | Neut | Chimeric (Mouse/Human) antibody |
| TAB-1179CL-F(E) | Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1179CL-F(E)) | Neut | Chimeric (Mouse/Human) Fab |
| TAB-1180CL-F(E) | Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1180CL-F(E)) | Neut | Chimeric (Mouse/Human) Fab |
| TAB-1182CL-F(E) | Anti-Human TNFSF13B Recombinant Antibody Fab Fragment (H1104-30-CA) | ELISA, Inhib | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1183CL | Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1183CL) | ELISA, Inhib | Mouse IgG2b, κ |
| TAB-1184CL | Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1184CL) | ELISA, Inhib | Mouse IgG2b, κ |
| TAB-1185CL | Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1185CL) | ELISA, Inhib | Mouse IgG2a, κ |
| TAB-1186CL | Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1186CL) | ELISA, Inhib | Mouse IgG3, κ |
| TAB-1187CL | Mouse Anti-TNFSF13B Recombinant Antibody (TAB-1187CL) | ELISA, Inhib | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1194CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1194CL) | Inhib | Humanized antibody |
| TAB-1195CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1195CL) | Inhib | Humanized antibody |
| TAB-1196CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1196CL) | Inhib | Humanized antibody |
| TAB-1197CL | Human Anti-TNFSF13B Recombinant Antibody (TAB-1197CL) | Inhib | Humanized antibody |
| TAB-1194CL-F(E) | Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (TAB-1194CL-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2184CQ | Rat Anti-TNFSF13B Recombinant Antibody (clone 8F10) | Neut, FC, IHC, IHC-Fr | Rat IgG2a |
| NEUT-2185CQ | Mouse Anti-TNFSF13B Recombinant Antibody (clone CBL701) | Neut | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3973 | Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI33DS) | WB, FC, IP | Rabbit IgG |
| MOR-4470 | Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI564DS) | FC | Rabbit IgG |
| MOR-4471 | Rabbit Anti-TNFSF13B Recombinant Antibody (clone SI565DS) | ELISA | Rabbit IgG |
| MOR-4537 | Rabbit Anti-TNFSF13B Recombinant Antibody (clone TH45DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0235-YC-S(P) | Human Anti-TNFSF13B Recombinant Antibody; scFv Fragment (HPAB-0235-YC-S(P)) | ELISA, Neut | Human scFv |
| HPAB-0730LY-S(P) | Human Anti-TNFSF13B Recombinant Antibody (clone CBL016); scfv Fragment | ELISA | Human scfv |
| HPAB-1255WJ-S(P) | Human Anti-B lymphocyte stimulator protein Recombinant Antibody; scFv Fragment (HPAB-1255WJ-S(P)) | ELISA, WB | Human scFv |
| HPAB-1256WJ-S(P) | Human Anti-B lymphocyte stimulator protein Recombinant Antibody; scFv Fragment (HPAB-1256WJ-S(P)) | ELISA, WB | Human scFv |
| HPAB-1257WJ-S(P) | Human Anti-B lymphocyte stimulator protein Recombinant Antibody; scFv Fragment (HPAB-1257WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0235-YC-F(E) | Human Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0235-YC-F(E)) | ELISA, Neut | Human Fab |
| HPAB-0121-FY-F(E) | Mouse Anti-TNFSF13B Recombinant Antibody; Fab Fragment (HPAB-0121-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-0730LY-F(E) | Human Anti-TNFSF13B Recombinant Antibody (clone CBL016); Fab Fragment | ELISA | Human Fab |
| HPAB-N0286-YC-F(E) | Human Anti-TNFSF13B Recombinant Antibody (clone h8E7D9C7F5-1); Fab Fragment | ELISA, FC, Inhib | Human Fab |
| FAMAB-0324JF-F(E) | Mouse Anti-TNFSF13B Recombinant Antibody (clone ABL-1); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-030 | Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-030) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-216 | Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-216) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1350 | AbPlus™ Anti-TNFSF13B Magnetic Beads (VS-0724-YC1350) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY47 | Human Anti-TNFSF13B (clone 10B1) scFv-Fc Chimera | ELISA, Neut | Human IgG1, scFv-Fc |
| VS-0125-FY48 | Human Anti-TNFSF13B (clone 1B5) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| VS-0425-FY68 | Human Anti-TNFSF13B scFv-Fc Chimera (VS-0425-FY68) | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY226 | CytoStream™ Mouse Anti-TNFSF13B Recombinant Antibody (clone H32-411) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7394 | Anti-TNFSF13B Immunohistochemistry Kit | IHC |
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