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    Rabbit Anti-VEGFA Recombinant Antibody (VS3-CJ676)

    CAT#: VS3-CJ676

    This product is a rabbit antibody that recognizes human, mouse, and rat VEGFA.

    Gene Expression
    ❮
    Figure 1 Cerebral cortex Figure 2 Thyroid gland Figure 3 Colon Figure 4 Liver Figure 5 Kidney Figure 6 Testis Figure 7 Lymph node Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG) Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)
    ❯

    Specifications

    • Immunogen
    • Recombinant protein
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse, Rat VEGFA
    • Species Reactivity
    • Human, Mouse, Rat
    • Applications
    • ICC, IF, IHC, IP, FC
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Protein A affinity purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • 40% Glycerol, 1% BSA, TBS, pH7.4.
    • Preservative
    • 0.05% Sodium Azide
    • Storage
    • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been tested for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry.

    Target

    • Alternative Names
    • VPF; VEGF; MVCD1
    • Sequence Similarities
    • Belongs to the PDGF/VEGF growth factor family.
    • Cellular Localization
    • Secreted
    • Function
    • Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
      Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437).
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    Downloadable Resources

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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS3-CJ676.pdf

    MSDS

    MSDS - VS3-CJ676.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Protocol & Troubleshooting

    Immunofluorescence (IF)
    Immunohistochemistry (IHC)

    We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

    Isotype Control

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

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