Human Anti-CA9 (clone G37) scFv-Fc Chimera
CAT#: VS-0325-FY54
An anti-CA9 scFv-Fc antibody is a recombinant antibody that combines the antigen-binding capabilities of a single-chain variable fragment (scFv) with the effector functions of an immunoglobulin's fragment crystallizable (Fc) region. CA9 stands for carbonic anhydrase IX. Anti-CA9 scFv-Fc antibodies have been used in research to treat renal cell carcinoma (RCC) cells. They have also been used in the development of bispecific antibodies that target both CA9 and CD55.



Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CA9
- Species Reactivity
- Human
- Clone
- G37
- Applications
- Flow Cytometry, ELISA, Inhibition
- Related Disease
- Renal cell carcinoma (RCC)
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 5 μg/mL
Target
- Alternative Names
- MN; CAIX
- Gene ID
- 768
- UniProt ID
- Q16790
- Long Name
- carbonic anhydrase 9
- Sequence Similarities
- Belongs to the alpha-carbonic anhydrase family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Asn-346 bears high-mannose type glycan structures.
Glycosylation at Thr115 and Asn346
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites, 4 O-linked glycans (2 sites)
- Protein Refseq
- XP_047279805.1; XP_047279806.1; XP_054219735.1; XP_054219736.1; NP_001207.2
- Function
- Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e.
bicarbonate and hydrogen ions).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "Clone G37"
- CAT
- Product Name
See other products for "CA9"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-707 | Anti-CAIX/CA9 Recombinant Antibody (Girentuximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
TAB-H43 | Anti-Human CA9 Recombinant Antibody (TAB-H43) | ELISA, IP, IF, Inhib | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1456CL | Anti-Human CA9 Recombinant Antibody (MSC1) | ELISA, FC, Inhib | Fully human antibody |
TAB-1457CL | Anti-Human CA9 Recombinant Antibody (MSC2) | ELISA, FC, Inhib | Fully human antibody |
TAB-1459CL | Anti-Human CA9 Recombinant Antibody (MSC4) | ELISA, FC, Inhib | Fully human antibody |
TAB-1460CL | Anti-Human CA9 Recombinant Antibody (MSC5) | ELISA, FC, Inhib | Fully human antibody |
TAB-1461CL | Anti-Human CA9 Recombinant Antibody (MSC6) | ELISA, FC, Inhib | Fully human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0427 | Hi-Affi™ Rabbit Anti-CA9 Recombinant Antibody (clone DS427AB) | IHC-P, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0355-CN | Mouse Anti-CA9 Recombinant Antibody (HPAB-0355-CN) | WB, ELISA, FC | Mouse IgG |
HPAB-0356-CN | Mouse Anti-CA9 Recombinant Antibody (HPAB-0356-CN) | WB, ELISA, FC | Mouse IgG |
HPAB-0357-CN | Mouse Anti-CA9 Recombinant Antibody (HPAB-0357-CN) | WB, ELISA, FC | Mouse IgG |
HPAB-0358-CN | Human Anti-CA9 Recombinant Antibody (HPAB-0358-CN) | WB, ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
HPAB-0359-CN | Human Anti-CA9 Recombinant Antibody (HPAB-0359-CN) | WB, ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0355-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0355-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
HPAB-0356-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0356-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
HPAB-0357-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0357-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
HPAB-0358-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0358-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
HPAB-0359-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0359-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0355-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0355-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
HPAB-0356-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0356-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
HPAB-0357-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0357-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
HPAB-0358-CN-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0358-CN-F(E)) | WB, ELISA, FC | Human Fab |
HPAB-0359-CN-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0359-CN-F(E)) | WB, ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H43 | Afuco™ Anti-CA9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H43) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY37 | AbPlus™ Anti-CA9 Magnetic Beads (12F10) | IP, Protein Purification | |
VS-0724-YC1029 | AbPlus™ Anti-CA9 Magnetic Beads (VS-0724-YC1029) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY290 | Anti-CA9 Immunohistochemistry Kit | IHC | |
VS-0525-XY911 | Anti-Mouse CA9 Immunohistochemistry Kit | IHC | |
VS-0525-XY912 | Anti-Human CA9 Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC94 | Recombinant Anti-CA9 Vesicular Antibody, EV Displayed (VS-0425-YC94) | ELISA, FC, Neut, Cell-uptake |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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