Rabbit Anti-GSK3A Polyclonal Antibody (MRO-1914-CN)

Name: Rabbit Anti-GSK3A Polyclonal Antibody (MRO-1914-CN)
SKU: MRO-1914-CN
Rating: 5 (1 reviews)

CAT#: MRO-1914-CN

This antibody is a rabbit polyclonal antibody that is capable of binding to GSK3A.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human heart muscle

Immunohistochemical staining of human heart muscle shows moderate membranous and cytoplasmic positivity in myocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28423/ihc_selected.jpg

Normal Tissue Figure 3 Lymph node

Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_A_9_8.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_B_7_5.jpg

Normal Tissue Figure 5 Colon

Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_A_7_3.jpg

Normal Tissue Figure 6 Liver

Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_A_9_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_A_8_5.jpg

Normal Tissue Figure 8 Testis

Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4422/12766_A_6_6.jpg

RNA Expression Figure 9 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105723-GSK3A

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Specifications

Immunogen
Peptide

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human GSK3A (Glycogen Synthase Kinase 3 Alpha)

Species Reactivity
Human

Applications
Used for immunoassay techniques such as: Western Blot; Immunofluorescence; Immunohistochemistry; Flow Cytometry

Conjugate
Unconjugated

Product Property

Purification
Peptide affinity purified

Format
Liquid

Buffer
1*TBS, pH 7.4, 1% BSA, 40% Glycerol

Preservative
0.05% Sodium Azide

Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Target

Alternative Names
Glycogen Synthase Kinase 3 Alpha; EC 2.7.11.26; Serine/Threonine-Protein Kinase GSK3A; GSK-3 Alpha; EC 2.7.11.1; EC 2.7.11;

Gene ID
2931

UniProt ID
P49840

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Related Signaling Pathways

BCR Signaling Pathway

Canonical Wnt Signaling Pathway

ErbB Signaling Pathway

Non-Canonical Wnt Signaling Pathway

PI3K-Akt Signaling Pathway

Related Diseases

Breast Cancer

Endometrial Cancer

Prostate Cancer

Throid Cancer

Hepatocellular Carcinoma

Insulin Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MRO-1914-CN.pdf

MSDS

MSDS - MRO-1914-CN.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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CAT	Product Name	Application
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