Recombinant Anti-CD40LG Vesicular Antibody, EV Displayed (VS-0425-YC389)
CAT#: VS-0425-YC389
The Recombinant Anti-CD40LG Vesicular Antibody, EV Displayed (VS-0425-YC389) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD40LG-expressed cells or tissues. The CD40LG is CD40 ligand, involved in immune signaling pathways, with mutations associated with immunodeficiency disorders.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line JURKAT
Immunofluorescent staining of human cell line JURKAT shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72480/2010_G3_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72480/2069_B6_2_blue_green.jpg
Normal Tissue
Figure 3 Colon
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72480/169295_A_9_3.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72480/169295_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102245-CD40LG
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD40LG
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD40 ligand
- Molecular Function
- Cytokine
- Cellular Localization
- Golgi apparatus, Plasma membrane
- Introduction
- CD40LG (CD40 Ligand) is a Protein Coding gene. Diseases associated with CD40LG include Immunodeficiency With Hyper-Igm, Type 1 and Cd40 Ligand Deficiency. Among its related pathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include cytokine activity and CD40 receptor binding.
- Alternative Names
- CD154, CD40-L, CD40L, gp39, hCD40L, HIGM1, IMD3, T-BAM, TNFSF5, TRAP
- Gene ID
- 959
- UniProt ID
- P29965
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Datasheet
MSDS
COA
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See other products for "CD40LG"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1071z | Mouse Anti-CD40LG Recombinant Antibody (clone 18C1) | ELISA, FC, FuncS, ICC, IF | Mouse IgG1 |
| HPAB-0585-WJ | Human Anti-CD40LG Recombinant Antibody (HPAB-0585-WJ) | ELISA | Human IgG |
| VS3-XY339 | Mouse Anti-CD40LG Recombinant Antibody, FITC (clone 4AM91) | FC, IF | Mouse IgG1 |
| VS3-XY340 | Mouse Anti-CD40LG Recombinant Antibody, PE (clone 4AM91) | FC, IF | Mouse IgG1 |
| VS3-XY341 | Mouse Anti-CD40LG Recombinant Antibody (clone 4AM91) | FC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-027 | Anti-Human CD40L Recombinant Antibody (TAB-027) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| TAB-210LC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (TAB-210LC-S(P)) | ELISA | Humanized scFv |
| TAB-211LC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (TAB-211LC-S(P)) | ELISA | Human scFv |
| TAB-210LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-210LC-F(E)) | ELISA | Humanized Fab |
| TAB-211LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-211LC-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G080E | Anti-Cd40lg immunotoxin LL2 (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G081E | Anti-Cd40lg immunotoxin LL2 (Fab)-PE | Cytotoxicity assay, Function study | |
| AGTO-L051P | anti-CD40LG immunotoxin MR1 (scFv)-PAP | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-127CL | Human Anti-CD40LG Recombinant Antibody (TAB-127CL) | ELISA | Human IgG |
| TAB-213LC | Human Anti-CD40LG Recombinant Antibody (TAB-213LC) | FC, ELISA, RBA | Human dAb |
| TAB-214LC | Human Anti-CD40LG Recombinant Antibody (TAB-214LC) | FC, ELISA, Inhib, RBA | Human dAb |
| TAB-215LC | Human Anti-CD40LG Recombinant Antibody (TAB-215LC) | FC, ELISA, Inhib, RBA | Human dAb |
| TAB-216LC | Human Anti-CD40LG Recombinant Antibody (TAB-216LC) | FC, ELISA, RBA | Human dAb |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-020 | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (PFBW-020) | Neut | Human Fab |
| FAMAB-0135-YC-F(E) | Hamster Anti-CD40LG Recombinant Antibody (clone mr-1); Fab Fragment | ELISA | Hamster Fab |
| HPAB-0744LY-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0744LY-F(E)) | ELISA | Human Fab |
| HPAB-0880LY-F(E) | Mouse Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0880LY-F(E)) | FC | Mouse Fab |
| HPAB-0585-WJ-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0585-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-020 | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (PSBW-020) | Neut | Human scFv |
| HPAB-0179-YC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0179-YC-S(P)) | ELISA | Human scFv |
| FAMAB-0135-YC-S(P) | Hamster Anti-CD40LG Recombinant Antibody (clone mr-1); scFv Fragment | ELISA | Hamster scFv |
| HPAB-0744LY-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0744LY-S(P)) | ELISA | Human scfv |
| HPAB-0585-WJ-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0585-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-212LC | Mouse Anti-Human CD40LG Recombinant Antibody (ABI793) | Block | |
| TAB-212LC-S(P) | Anti-Human CD40LG Recombinant Antibody scFv Fragment (ABI793) | ELISA | |
| TAB-212LC-F(E) | Anti-Human CD40LG Recombinant Antibody Fab Fragment (ABI793) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-225LC | Anti-Human CD40LG Recombinant Antibody (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
| TAB-225LC-S(P) | Anti-Human CD40LG Recombinant Antibody scFv Fragment (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
| TAB-225LC-F(E) | Anti-Human CD40LG Recombinant Antibody Fab Fragment (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-368CQ | Mouse Anti-CD40LG Recombinant Antibody (clone 24-31) | FC, Block, IF | Mouse IgG1, κ |
| NEUT-375CQ | Hamster Anti-CD40LG Recombinant Antibody (clone MR1) | IHC-Fr, FC, IP, Block | Hamster IgG1, κ |
| NEUT-377CQ | Hamster Anti-CD40LG Recombinant Antibody (clone MAB0820) | Block, FC, IHC-Fr | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-369CQ | Mouse Anti-CD40LG Recombinant Antibody (clone CBL300) | FC, IHC, CyTOF, Neut, WB | Mouse IgG2b |
| NEUT-370CQ | Mouse Anti-CD40LG Recombinant Antibody (clone LL2) | Neut, ELISA, FC, FuncS, IF | Mouse IgG1 |
| NEUT-371CQ | Mouse Anti-CD40LG Recombinant Antibody (clone LL48) | Neut, FuncS, IF | Mouse IgG2a |
| NEUT-372CQ | Mouse Anti-CD40LG Recombinant Antibody (NEUT-372CQ) | Neut | Mouse IgG2b |
| NEUT-374CQ | Rat Anti-CD40LG Recombinant Antibody (clone CBL719) | FC, CyTOF, Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0561 | Hi-Affi™ Rabbit Anti-CD40LG Recombinant Antibody (clone DS561AB) | WB, FC | Rabbit IgG |
| MOR-0562 | Hi-Affi™ Rabbit Anti-CD40LG Recombinant Antibody (clone DS562AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0610LC | Mouse Anti-CD40LG Recombinant Antibody (clone h5c8) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-022CN | Human Anti-CD40LG Recombinant Antibody (NS-022CN) | ELISA, FC | Human IgG |
| NS-022CN-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (NS-022CN-F(E)) | ELISA, FC | Human Fab |
| NS-022CN-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (NS-022CN-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-027 | Afuco™ Anti-CD40LG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-027) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-876 | Afuco™ Anti-CD40LG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-876) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC164 | CytoStream™ Rabbit Anti-CD40LG Recombinant Antibody (VS13-YC164) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY79 | Human Anti-CD40LG (clone YMF323.6) scFv-Fc Chimera | FC, ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1182 | Anti-CD40LG Immunohistochemistry Kit | IHC | |
| VS-0525-XY1183 | Anti-Mouse CD40LG Immunohistochemistry Kit | IHC |
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