Hamster Anti-CD40LG Recombinant Antibody (clone mr-1) (CAT#: FAMAB-0135YC)
The monoclonal antibody recognizes mouse CD154, a 39 kDa transmembrane glycoprotein also referred to as CD40 ligand (CD40L). This antibody has been employed in various FACS analyses for diverse immunological applications. For example, it has been used to demonstrate the constitutive expression of CD40L on naive CD4 T cells and its role in enhancing the survival of autoreactive B cells. Additionally, it has been utilized to establish the pivotal role of the interaction between natural killer cells and dendritic cells in the sensitization phase of contact hypersensitivity. Furthermore, it has been employed to show that enhanced CD8 T cell responses, facilitated by GITR-mediated costimulation, can effectively resolve chronic viral infections.
Specific Inquiry
ELISA
Figure 1 MR-1 and clodronate liposomes prolong transgene expression and inhibit immune responses to vector.
FIX levels in plasma were determined by ELISA.
Stein, C. S., Pemberton, J. L., Van Rooijen, N., & Davidson, B. L. (1998). Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus. Gene Therapy, 5(4), 431-439.
Specifications
- Host Species
- Hamster
- Type
- Hamster IgG
- Specificity
- Mouse CD40LG
- Species Reactivity
- Mouse
- Clone
- mr-1
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5; Tnlg8b
- Gene ID
- 21947
- UniProt ID
- P27548
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-027 | Anti-Human CD40L Recombinant Antibody (Ruplizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| TAB-876 | Anti-Human CD40 ligand Recombinant Antibody (Toralizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
| TAB-211LC | Human Anti-CD40LG Recombinant Antibody (TAB-211LC) | ELISA | Human IgG, κ |
| TAB-210LC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (TAB-210LC-S(P)) | ELISA | Humanized scFv |
| TAB-211LC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (TAB-211LC-S(P)) | ELISA | Human scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G080E | Anti-Cd40lg immunotoxin LL2 (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G081E | Anti-Cd40lg immunotoxin LL2 (Fab)-PE | Cytotoxicity assay, Function study | |
| AGTO-L051P | anti-CD40LG immunotoxin MR1 (scFv)-PAP | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-020 | Human Anti-CD40LG Recombinant Antibody (PABW-020) | Neut | Human IgG1, κ |
| HPAB-0179-YC | Human Anti-CD40LG Recombinant Antibody (HPAB-0179-YC) | ELISA | Human IgG1 |
| HPAB-0744LY | Human Anti-CD40LG Recombinant Antibody (HPAB-0744LY) | Inhib | Human IgG |
| HPAB-0880LY | Mouse Anti-CD40LG Recombinant Antibody (HPAB-0880LY) | FC | Mouse IgG1 |
| HPAB-0881LY | Mouse Anti-CD40LG Recombinant Antibody (HPAB-0881LY) | FC | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-020 | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (PFBW-020) | Neut | Human Fab |
| HPAB-0179-YC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0179-YC-F(E)) | ELISA | Human Fab |
| FAMAB-0135-YC-F(E) | Hamster Anti-CD40LG Recombinant Antibody (clone mr-1); Fab Fragment | ELISA | Hamster Fab |
| HPAB-0744LY-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0744LY-F(E)) | ELISA | Human Fab |
| HPAB-0585-WJ-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (HPAB-0585-WJ-F(E)) | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-212LC | Mouse Anti-Human CD40LG Recombinant Antibody (ABI793) | Block | |
| TAB-212LC-S(P) | Anti-Human CD40LG Recombinant Antibody scFv Fragment (ABI793) | ELISA | |
| TAB-212LC-F(E) | Anti-Human CD40LG Recombinant Antibody Fab Fragment (ABI793) | ELISA |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-225LC | Anti-Human CD40LG Recombinant Antibody (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
| TAB-225LC-S(P) | Anti-Human CD40LG Recombinant Antibody scFv Fragment (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
| TAB-225LC-F(E) | Anti-Human CD40LG Recombinant Antibody Fab Fragment (YMF323.6) | ELISA | Chimeric antibody (hamster/human) |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-213LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-213LC-F(E)) | FC, ELISA, RBA | |
| TAB-214LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-214LC-F(E)) | FC, ELISA, RBA | |
| TAB-215LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-215LC-F(E)) | FC, ELISA, RBA | |
| TAB-216LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-216LC-F(E)) | FC, ELISA, RBA | |
| TAB-217LC-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (TAB-217LC-F(E)) | FC, ELISA, RBA |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-368CQ | Mouse Anti-CD40LG Recombinant Antibody (clone 24-31) | FC, Block, IF | Mouse IgG1, κ |
| NEUT-375CQ | Hamster Anti-CD40LG Recombinant Antibody (clone MR1) | IHC-Fr, FC, IP, Block | Hamster IgG1, κ |
| NEUT-377CQ | Hamster Anti-CD40LG Recombinant Antibody (clone MAB0820) | Block, FC, IHC-Fr | Hamster IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-369CQ | Mouse Anti-CD40LG Recombinant Antibody (clone CBL300) | FC, IHC, CyTOF, Neut, WB | Mouse IgG2b |
| NEUT-370CQ | Mouse Anti-CD40LG Recombinant Antibody (clone LL2) | Neut, ELISA, FC, FuncS, IF | Mouse IgG1 |
| NEUT-371CQ | Mouse Anti-CD40LG Recombinant Antibody (clone LL48) | Neut, FuncS, IF | Mouse IgG2a |
| NEUT-372CQ | Mouse Anti-CD40LG Recombinant Antibody (clone 13H5) | Neut | Mouse IgG2b |
| NEUT-374CQ | Rat Anti-CD40LG Recombinant Antibody (clone CBL719) | FC, CyTOF, Neut | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0561 | Hi-Affi™ Rabbit Anti-CD40LG Recombinant Antibody (clone DS561AB) | WB, FC | Rabbit IgG |
| MOR-0562 | Hi-Affi™ Rabbit Anti-CD40LG Recombinant Antibody (clone DS562AB) | ELISA | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0610LC | Mouse Anti-CD40LG Recombinant Antibody (clone h5c8) | ELISA | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0179-YC-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0179-YC-S(P)) | ELISA | Human scFv |
| HPAB-0880LY-S(P) | Mouse Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0880LY-S(P)) | FC | Mouse scFv |
| HPAB-0881LY-S(P) | Mouse Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0881LY-S(P)) | FC | Mouse scFv |
| HPAB-0882LY-S(P) | Mouse Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0882LY-S(P)) | FC | Mouse scFv |
| HPAB-0585-WJ-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (HPAB-0585-WJ-S(P)) | ELISA | Human scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-022CN | Human Anti-CD40LG Recombinant Antibody (NS-022CN) | ELISA, FC | Human IgG |
| NS-022CN-F(E) | Human Anti-CD40LG Recombinant Antibody; Fab Fragment (NS-022CN-F(E)) | ELISA, FC | Human Fab |
| NS-022CN-S(P) | Human Anti-CD40LG Recombinant Antibody; scFv Fragment (NS-022CN-S(P)) | ELISA, FC | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-027 | Afuco™ Anti-CD40LG ADCC Recombinant Antibody (Ruplizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-876 | Afuco™ Anti-CD40LG ADCC Recombinant Antibody (Toralizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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