Recombinant Mouse Anti-ENG Antibody (clone 2B2H2)
CAT#: VS3-FY232
This product is a recombinant mouse antibody that recognizes ENG protein. This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Flow Cytometry.






Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- ENG
- Clone
- 2B2H2
- Applications
- Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Flow Cytometry
- Conjugate
- Unconjugated
Product Property
- Purity
- >95%
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Flow Cytometry.
Target
- Alternative Names
- Endoglin; CD105 Antigen; END; Osler-Rendu-Weber Syndrome 1; HHT1; ORW1
- Gene ID
- 2022
- UniProt ID
- P17813
- Cellular Localization
- Cell membrane, Membrane
- Protein Refseq
- NP_000109.1; NP_001108225.1; NP_001265067.1
- Function
- Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529).
Required for normal structure and integrity of adult vasculature (PubMed:7894484).
Regulates the migration of vascular endothelial cells (PubMed:17540773).
Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity).
May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity).
May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830).
Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410, PubMed:21737454, PubMed:22347366, PubMed:23300529).
Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1573CL | Mouse Anti-ENG Recombinant Antibody (TAB-1573CL) | FC, Apop | Mouse IgG |
TAB-1573CL-S(P) | Mouse Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1573CL-S(P)) | FC, Apop | Mouse scFv |
TAB-1574CL-S(P) | Mouse Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1574CL-S(P)) | FC | Mouse scFv |
TAB-1573CL-F(E) | Mouse Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1573CL-F(E)) | FC, Apop | Mouse Fab |
TAB-1574CL-F(E) | Mouse Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1574CL-F(E)) | FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1575CL | Human Anti-ENG Recombinant Antibody (TAB-1575CL) | Apop | Humanized antibody |
TAB-1575CL-S(P) | Human Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1575CL-S(P)) | Apop | Human scFv |
TAB-1576CL-S(P) | Human Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1576CL-S(P)) | Cyt, ELISA, FC, FuncS | Human scFv |
TAB-1575CL-F(E) | Human Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1575CL-F(E)) | Apop | Humanized Fab |
TAB-1576CL-F(E) | Human Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1576CL-F(E)) | Cyt, ELISA, FC, FuncS | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1569CL-S(P) | Human Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1569CL-S(P)) | ELISA, FC | Human scFv |
TAB-1571CL-S(P) | Human Anti-ENG Recombinant Antibody; scFv Fragment (TAB-1571CL-S(P)) | ELISA, FC | Human scFv |
TAB-1577CL-S(P) | Anti-Human ENG Recombinant Antibody scFv Fragment (9H10) | FuncS | Fully human antibody |
TAB-1569CL-F(E) | Human Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1569CL-F(E)) | ELISA, FC | Human Fab |
TAB-1571CL-F(E) | Human Anti-ENG Recombinant Antibody; Fab Fragment (TAB-1571CL-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0189MZ | Chicken Anti-Endoglin Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-726CQ | Mouse Anti-ENG Recombinant Antibody (clone 7D11) | WB, Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1150 | Hi-Affi™ Rabbit Anti-ENG Recombinant Antibody (clone DS1150AB) | WB, IHC-P, IP, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-013ML | Anti-Human ENG Recombinant Antibody (TAB-013ML) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0231-YC | Human Anti-ENG Recombinant Antibody (clone Vκ2VH1) | ELISA, WB, FuncS | Humanized IgG |
HPAB-0713-CN | Human Anti-ENG Recombinant Antibody (clone 6B10) | WB, FC | Human IgG |
HPAB-0714-CN | Human Anti-ENG Recombinant Antibody (clone 4.120) | WB, FC | Human IgG |
HPAB-0162CQ | Mouse Anti-ENG Recombinant Antibody (clone E9) | ELISA, WB, FC, IHC, IHC-Fr, IP | Mouse IgG1 |
HPAB-0448-FY | Rat Anti-ENG Recombinant Antibody (HPAB-0448-FY) | ELISA, Inhib, FuncS | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0231-YC-S(P) | Human Anti-ENG Recombinant Antibody (clone Vκ2VH1); scFv Fragment | ELISA, WB, FuncS | Humanized scFv |
HPAB-0448-FY-S(P) | Rat Anti-ENG Recombinant Antibody; scFv Fragment (HPAB-0448-FY-S(P)) | ELISA, Inhib, FuncS | Rat scFv |
HPAB-AP642-YC-S(P) | Human Anti-ENG Recombinant Antibody (clone Vκ1VH1); scFv Fragment | ELISA | Humanized scFv |
HPAB-AP644-YC-S(P) | Human Anti-ENG Recombinant Antibody (clone Vκ2VH2); scFv Fragment | ELISA | Humanized scFv |
HPAB-J0071-YC-S(P) | Mouse Anti-ENG Recombinant Antibody (clone AP020/YC); scFv Fragment | ELISA, WB, ICC, IHC, IF, FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0231-YC-F(E) | Human Anti-ENG Recombinant Antibody (clone Vκ2VH1); Fab Fragment | ELISA, WB, FuncS | Humanized Fab |
HPAB-0713-CN-F(E) | Human Anti-ENG Recombinant Antibody (clone 6B10); Fab Fragment | WB, FC | Human Fab |
HPAB-0714-CN-F(E) | Human Anti-ENG Recombinant Antibody (clone 4.120); Fab Fragment | WB, FC | Human Fab |
HPAB-0448-FY-F(E) | Rat Anti-ENG Recombinant Antibody; Fab Fragment (HPAB-0448-FY-F(E)) | ELISA, Inhib, FuncS | Rat Fab |
HPAB-J0071-YC-F(E) | Mouse Anti-ENG Recombinant Antibody (clone AP020/YC); Fab Fragment | ELISA, WB, ICC, IHC, IF, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-013ML | Afuco™ Anti-ENG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-013ML) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0613 | PE-A*02:01/Human ENG (LLTAALWYV) MHC Tetramer | FCM, IHC | |
MHC-CN0614 | APC-A*02:01/Human ENG (LLTAALWYV) MHC Tetramer | FCM, IHC | |
MHC-CN0615 | FITC-A*02:01/Human ENG (LLTAALWYV) MHC Tetramer | FCM, IHC | |
MHC-CN0616 | A*02:01/Human ENG (LLTAALWYV) MHC Tetramer | FCM, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0707-YJ-VHH | Camelid Anti-ENG Recombinant Single Domain Antibody (HPAB-0707-YJ-VHH) | ELISA, ICC | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0724-YC1247 | AbPlus™ Anti-ENG Magnetic Beads (VS-0724-YC1247) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-1024-XY186 | Mouse Anti-NHP ENG Recombinant Antibody (clone ENG/1621) | IF, FC | Mouse IgG1, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0225-XY103 | CytoStream™ Mouse Anti-ENG Recombinant Antibody (VS-0225-XY103) | FC | Mouse IgG1, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-FY146 | Human Anti-ENG (clone 6B10) scFv-Fc Chimera | WB, FC, ADCC | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC237 | Recombinant Anti-ENG Vesicular Antibody, EV Displayed (VS-0425-YC237) | Cyt, ELISA, FC, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY2282 | Anti-Mouse ENG Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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