Recombinant Anti-KIT Vesicular Antibody, EV Displayed (VS-0425-YC461)
CAT#: VS-0425-YC461
The Recombinant Anti-KIT Vesicular Antibody, EV Displayed (VS-0425-YC461) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to KIT-expressed cells or tissues. The KIT is a receptor tyrosine kinase linked to conditions like gastrointestinal tumors and mast cell disorders.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg
Normal Tissue
Figure 2 High expression in breast
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg
Normal Tissue
Figure 3 High expression in lung.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg
Normal Tissue
Figure 4 Skin
Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (HEL, HMC-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- KIT
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Cynomolgus
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- KIT proto-oncogene, receptor tyrosine kinase
- Molecular Function
- Kinase, Receptor, Transferase, Tyrosine-protein kinase
- Cellular Localization
- Plasma membrane
- Introduction
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- C-Kit, CD117, PBT, SCFR
- Gene ID
- 3815
- UniProt ID
- P10721
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-470CL | Human Anti-KIT Recombinant Antibody (TAB-470CL) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-450CL | Afuco™ Anti-KIT Recombinant Antibody (AFC-450CL), ADCC Enhanced | ELISA, WB | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-255 | Human Anti-KIT Recombinant Antibody (clone Fab19) | WB, ELISA, FuncS | Human IgG |
| MRO-1775-CN | Rabbit Anti-KIT Polyclonal Antibody (MRO-1775-CN) | WB, IF, FC | Rabbit IgG |
| ZG-0426F | Mouse Anti-KIT Recombinant Antibody (ZG-0426F) | WB, IHC, ELISA | Mouse IgG |
| ZG-0427F | Mouse Anti-KIT Recombinant Antibody (ZG-0427F) | WB, IHC, ELISA | Mouse IgG |
| VS3-QX639 | Mouse Anti-KIT Recombinant Antibody (clone 7F12-E6-D7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-625 | Human Anti-KIT Recombinant Antibody (clone 19); Fab Fragment | ELISA | Human Fab |
| PFBL-637 | Mouse Anti-KIT Recombinant Antibody Fab Fragment (PFBL-637) | WB, FuncS | Mouse Fab |
| FAMAB-0024-CN-F(E) | Mouse Anti-KIT Recombinant Antibody (clone Kit2C75); Fab Fragment | FC | Mouse Fab |
| HPAB-N0156-YC-F(E) | Mouse Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0156-YC-F(E)) | ELISA, Inhib, FuncS | Mouse Fab |
| HPAB-N0157-YC-F(E) | Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0157-YC-F(E)) | ELISA, Inhib, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-625 | Human Anti-KIT Recombinant Antibody (clone 19); scFv Fragment | ELISA | Human scFv |
| PSBL-637 | Mouse Anti-KIT Recombinant Antibody scFv Fragment (PSBL-637) | WB, FuncS | Mouse scFv |
| FAMAB-0024-CN-S(P) | Mouse Anti-KIT Recombinant Antibody (clone Kit2C75); scFv Fragment | FC | Mouse scFv |
| HPAB-N0156-YC-S(P) | Mouse Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0156-YC-S(P)) | ELISA, Inhib, FuncS | Mouse scFv |
| HPAB-N0157-YC-S(P) | Human Anti-KIT Recombinant Antibody; scFv Fragment (HPAB-N0157-YC-S(P)) | ELISA, Inhib, FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-465LC | Human Anti-KIT Recombinant Antibody (TAB-465LC) | ELISA, SPR | Human antibody |
| TAB-466LC | Human Anti-KIT Recombinant Antibody (TAB-466LC) | ELISA, SPR | Human antibody |
| TAB-465LC-S(P) | Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-465LC-S(P)) | FC, WB, SPR, ELISA | Human scFv |
| TAB-466LC-S(P) | Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-466LC-S(P)) | FC, WB, SPR, ELISA | Human scFv |
| TAB-468LC-S(P) | Human Anti-KIT Recombinant Antibody; scFv Fragment (TAB-468LC-S(P)) | FC, WB, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0316MZ | Chicken Anti-KIT Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1629CQ | Recombinant Mouse Anti-KIT Antibody (A3C6E2) | FC, BL | IgG1, κ |
| NEUT-1633CQ | Recombinant Rat Anti-Kit Antibody (ACK2) | FC, BL, Depletion | IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1630CQ | Recombinant Mouse Anti-KIT Antibody (CBL788) | WB, FC, CyTOF, ELISA(Cap), Neut | IgG1 |
| NEUT-1631CQ | Recombinant Mouse Anti-KIT Antibody (14G5) | Neut, WB | IgG1 |
| NEUT-1632CQ | Recombinant Mouse Anti-KIT Antibody (12A8) | WB, IP, FC, Neut | IgG1 |
| NEUT-1634CQ | Recombinant Mouse Anti-KIT Antibody (CBL158) | Neut, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1948 | Hi-Affi™ Recombinant Rabbit Anti-KIT Monoclonal Antibody (DS1948AB) | IHC-P, IHC-Fr | IgG |
| MOR-4551 | Hi-Affi™ Recombinant Rabbit Anti-KIT Monoclonal Antibody (TH61DS) | WB, IF, ICC | IgG |
| MOR-4552 | Hi-Affi™ Recombinant Rabbit Anti-KIT Monoclonal Antibody (TH62DS) | WB, IF, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX638 | Mouse Anti-KIT Recombinant Antibody (clone 566CT8.5.4) | WB, ICC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1349 | AbPlus™ Anti-Kit Magnetic Beads (VS-0724-YC1349) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC33 | Mouse Anti-KIT Recombinant Antibody (VS-0924-YC33) - Cancer Stem Cell Marker | IHC, WB | |
| VS-0924-YC34 | Rabbit Anti-KIT Antibody (VS-0924-YC34) - Cancer Stem Cell Marker | IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY127 | Mouse Anti-NHP KIT Recombinant Antibody (clone 104D2) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY154 | CytoStream™ Mouse Anti-KIT Recombinant Antibody (clone 104D2) | FC | Mouse IgG1 |
| VS-0225-XY155 | CytoStream™ Rat Anti-KIT Recombinant Antibody (clone ACK45) | FC | Rat IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY38 | Human Anti-KIT scFv-Fc Chimera (VS-0325-FY38) | Inhib, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3787 | Anti-KIT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3788 | Anti-Mouse KIT Immunohistochemistry Kit | IHC |
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