Recombinant Anti-TSHR Vesicular Antibody, EV Displayed (VS-0425-YC579) (CAT#: VS-0425-YC579)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• TSHR

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Mouse, Rat, Cat, Dog, Sheep

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Thyroid stimulating hormone receptor

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Introduction
• The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

• Alternative Names
• LGR3

• Gene ID
• 7253

• UniProt ID
• P16473

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