Human Anti-TSHR Recombinant Antibody (clone M22); Fab Fragment (CAT#: PFBW-172)
Recombinant Human Antibody (M22) Fab Fragment is specific to TSHR, expressed in Chinese Hamster Ovary cells (CHO). A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A° resolution.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg

(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg

(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000165409-TSHR

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
Specifications
- Immunogen
- Human thyroid stimulating hormone receptor
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human TSHR
- Species Reactivity
- Human
- Clone
- M22
- Applications
- WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TSHR; thyroid stimulating hormone receptor; LGR3; CHNG1; hTSHR-I; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
- Gene ID
- 7253
- UniProt ID
- P16473
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-353 | Mouse Anti-TSHR Recombinant Antibody scFv Fragment (PSBL-353) | WB, ELISA, FuncS | Mouse scFv |
PSBL-730 | Human Anti-TSHR Recombinant Antibody scFv Fragment (PSBL-730) | Block | Human scFv |
PSBW-172 | Human Anti-TSHR Recombinant Antibody (clone M22); scFv Fragment | WB | Human scFv |
HPAB-0328CQ-S(P) | Mouse Anti-TSHR Recombinant Antibody; scFv Fragment (HPAB-0328CQ-S(P)) | ELISA, FC, FuncS | Mouse scFv |
HPAB-0329CQ-S(P) | Mouse Anti-TSHR Recombinant Antibody; scFv Fragment (HPAB-0329CQ-S(P)) | ELISA, FC, FuncS, Agonist | Mouse scFv |
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