Human Anti-TSHR Recombinant Antibody (clone M22); Fab Fragment (CAT#: PFBW-172)
Recombinant Human Antibody (M22) Fab Fragment is specific to TSHR, expressed in Chinese Hamster Ovary cells (CHO). A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A° resolution.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg
Figure 2 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000165409-TSHR
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000165409-TSHR
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
Specifications
- Immunogen
- Human thyroid stimulating hormone receptor
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human TSHR
- Species Reactivity
- Human
- Clone
- M22
- Applications
- WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TSHR; thyroid stimulating hormone receptor; LGR3; CHNG1; hTSHR-I; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
- Gene ID
- 7253
- UniProt ID
- P16473
Related Resources
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone M22"
See other products for "TSHR"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Mouse Antibody Products
Human Antibody Products
Blocking Antibody Products
IgM Antibody Products
Antibody Magnetic Beads
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1074z | Mouse Anti-TSHR Recombinant Antibody (clone 9B2) | WB, ELISA, FC, IP, FuncS | Mouse IgG1 |
| PABL-353 | Mouse Anti-TSHR Recombinant Antibody (PABL-353) | WB, ELISA, FuncS | Mouse IgG |
| PABL-722 | Human Anti-TSHR Recombinant Antibody (clone M22) | WB, IF, FuncS | Human IgG |
| PABW-172 | Recombinant Human Anti-TSHR Antibody (M22) | WB, ELISA, PK | IgG |
| FAMAB-0324CQ | Mouse Anti-TSHR Recombinant Antibody (clone D2) | ELISA | Mouse IgM |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PFBW-172. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: Neut, IHC, Activ, FuncS, IF, ELISA
Application: ELISA, Inhib, FC, Neut
Application: ELISA, WB, Microarray, Block
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, Block, WB, FC, IP
-1.png)
Application: WB, ELISA, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
