Human Anti-TSHR Recombinant Antibody (clone M22); scFv Fragment (CAT#: PSBW-172)
Recombinant Human Antibody (M22) scFv Fragment is specific to TSHR, expressed in E. coli. A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A° resolution.
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Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg
Figure 2 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000165409-TSHR
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000165409-TSHR
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
Specifications
- Immunogen
- Human thyroid stimulating hormone receptor
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human TSHR
- Species Reactivity
- Human
- Clone
- M22
- Applications
- WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TSHR; thyroid stimulating hormone receptor; LGR3; CHNG1; hTSHR-I; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
- Gene ID
- 7253
- UniProt ID
- P16473
Related Resources
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1074z | Mouse Anti-TSHR Recombinant Antibody (clone 9B2) | WB, ELISA, FC, IP, FuncS | Mouse IgG1 |
| PABL-353 | Mouse Anti-TSHR Recombinant Antibody (PABL-353) | WB, ELISA, FuncS | Mouse IgG |
| PABL-722 | Human Anti-TSHR Recombinant Antibody (clone M22) | WB, IF, FuncS | Human IgG |
| FAMAB-0324CQ | Mouse Anti-TSHR Recombinant Antibody (clone D2) | ELISA | Mouse IgM |
| HPAB-0367LY | Human Anti-TSHR Recombinant Antibody (clone 5C9) | Block, ELISA | Human IgG1 |
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