Human Anti-TSHR Recombinant Antibody (clone M22); scFv Fragment
CAT#: PSBW-172
Recombinant Human Antibody (M22) scFv Fragment is specific to TSHR, expressed in E. coli. A human monoclonal autoantibody to the TSHR (M22), which is a powerful thyroid stimulator with high affinity for the receptor, and determined its crystal structure at 1.65A° resolution.
Gene Expression
Normal Tissue
Figure 1 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_B_3_5.jpg
Normal Tissue
Figure 2 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/473/63994_A_6_6.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, SCLC-21H, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165409-TSHR
❮
❯
Specifications
- Immunogen
- Human thyroid stimulating hormone receptor
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human TSHR
- Species Reactivity
- Human
- Clone
- M22
- Applications
- WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
Autoimmune Thyroid Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-353 | Mouse Anti-TSHR Recombinant Antibody (PABL-353) | WB, ELISA, FuncS | Mouse IgG |
| PABL-722 | Human Anti-TSHR Recombinant Antibody (clone M22) | WB, IF, FuncS | Human IgG |
| PABL-737 | Human Anti-TSHR Recombinant Antibody (clone K1-70) | Block | Human IgG |
| PABW-172 | Recombinant Human Anti-TSHR Antibody (M22) | WB, ELISA, PK | IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-353 | Mouse Anti-TSHR Recombinant Antibody scFv Fragment (PSBL-353) | WB, ELISA, FuncS | Mouse scFv |
| PSBL-730 | Human Anti-TSHR Recombinant Antibody scFv Fragment (PSBL-730) | Block | Human scFv |
| FAMAB-0323CQ-S(P) | Mouse Anti-TSHR Recombinant Antibody (clone 4G11); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0328CQ-S(P) | Mouse Anti-TSHR Recombinant Antibody; scFv Fragment (HPAB-0328CQ-S(P)) | ELISA, FC, FuncS | Mouse scFv |
| HPAB-0329CQ-S(P) | Mouse Anti-TSHR Recombinant Antibody; scFv Fragment (HPAB-0329CQ-S(P)) | ELISA, FC, FuncS, Agonist | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-730 | Human Anti-TSHR Recombinant Antibody Fab Fragment (PFBL-730) | Block | Human Fab |
| PFBW-172 | Human Anti-TSHR Recombinant Antibody (clone M22); Fab Fragment | WB | Human Fab |
| FAMAB-0323CQ-F(E) | Mouse Anti-TSHR Recombinant Antibody (clone 4G11); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0324CQ-F(E) | Mouse Anti-TSHR Recombinant Antibody (clone D2); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0367LY-F(E) | Human Anti-TSHR Recombinant Antibody (clone 5C9); Fab Fragment | Block, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-189CQ | Mouse Anti-TSHR Recombinant Antibody (TAB-189CQ) | ELISA, BL | Mouse IgG |
| TAB-190CQ | Mouse Anti-TSHR Recombinant Antibody (TAB-190CQ) | ELISA, BL | Mouse IgG |
| TAB-189CQ-F(E) | Mouse Anti-TSHR Recombinant Antibody; Fab Fragment (TAB-189CQ-F(E)) | ELISA, BL | Mouse Fab |
| TAB-190CQ-F(E) | Mouse Anti-TSHR Recombinant Antibody; Fab Fragment (TAB-190CQ-F(E)) | ELISA, BL | Mouse Fab |
| TAB-192CQ-F(E) | Mouse Anti-TSHR Recombinant Antibody; Fab Fragment (TAB-192CQ-F(E)) | ELISA, WB, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-191CQ | Human Anti-TSHR Recombinant Antibody (TAB-191CQ) | ELISA, WB, Inhib | Human IgG |
| TAB-191CQ-S(P) | Human Anti-TSHR Recombinant Antibody; scFv Fragment (TAB-191CQ-S(P)) | ELISA, WB, Inhib | Human scFv |
| TAB-191CQ-F(E) | Human Anti-TSHR Recombinant Antibody; Fab Fragment (TAB-191CQ-F(E)) | ELISA, WB, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2234CQ | Mouse Anti-TSHR Recombinant Antibody (clone 49) | Block, ELISA, ICC, IF, IP, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0323CQ | Mouse Anti-TSHR Recombinant Antibody (clone 4G11) | ELISA, Inhib | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY264 | AbPlus™ Anti-TSHR Magnetic Beads (49) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC579 | Recombinant Anti-TSHR Vesicular Antibody, EV Displayed (VS-0425-YC579) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7572 | Anti-TSHR Immunohistochemistry Kit | IHC |
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