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INS

Anti-INS Products

PE-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1682)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: PE
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PE-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC905)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: PE
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PE-DQB1*03:02/Human INS (LVEALYLVCGERGG) MHC Tetramer (MHC-LC1148)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: PE
Compare

APC-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC906)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: APC
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PE-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC962)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: PE
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BV421-A*02:01/Human INS (AQWGPDPAAA) MHC Tetramer (MHC-LC907)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: AQWGPDPAAA
- Conjugate: BV421
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APC-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC963)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: APC
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APC-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC978)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: APC
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APC-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1683)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: APC
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BV421-DRB1*04:01/Human INS (GSLQPLALEGSLQKRG) MHC Tetramer (MHC-LC964)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GSLQPLALEGSLQKRG
- Conjugate: BV421
Compare

BV421-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC979)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: BV421
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BV421-A*02:01/Human INS (ALWGPDPAAA) MHC Tetramer (MHC-LC1684)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: ALWGPDPAAA
- Conjugate: BV421
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Recombinant Mouse Anti-Insulin/Proinsulin Antibody (clone E7C5) (MOB-0152MZ)
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-Fr
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PE-H2-K1/Human INS (LYLVCGERG) MHC Tetramer (MHC-LC977)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERG
- Conjugate: PE
Compare

PE-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC980)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: PE
Compare

PE-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC983)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: PE
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Mouse Anti-INS Recombinant Antibody (MOB-0058F) (MOB-0058F)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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Mouse Anti-INS Recombinant Antibody (MOB-0059F) (MOB-0059F)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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PE-DQB1*03:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3234)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DQB1*02:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3235)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

Recombinant Human Anti-INS Soluble TCR (clone FS17) (scTCR-157CQ-S(P))
- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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Recombinant Human Anti-INS Soluble TCR (clone FS18) (scTCR-158CQ-S(P))
- Species Reactivity: Human
- Epitope: GSLQPLALEGSLQKRG
- MHC: HLA-DR4
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Recombinant Mouse Anti-INS Soluble TCR (clone G9C8) (scTCR-159CQ-S(P))
- Species Reactivity: Human
- Epitope: LYLVCGERG
- MHC: H-2Kd
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Recombinant Human Anti-INS Soluble TCR (clone 1C8) (scTCR-357CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Recombinant Human Anti-INS Soluble TCR (clone 1E6) (scTCR-358CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Mouse Anti-INS Recombinant Antibody (clone 123) (FAMAB-0182YC)
- Species Reactivity: Bovine
- Type: Mouse IgG1
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 124) (FAMAB-0183YC)
- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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Rabbit Anti-INS Recombinant Antibody (clone CBACN-307) (MRO-0842-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC
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Mouse Anti-INS Recombinant Antibody (clone A6-6) (MRO-0843-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: IHC, ELISA
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Human Anti-INS Recombinant Antibody (clone mAb48) (HPAB-1993-FY)
- Species Reactivity: Human
- Type: Human IgG3, κ
- Application: ELISA
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-2) (scTCR-0546YC-S(P))
- Epitope: AQWGPDPAAA
- MHC: HLA-A02
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-3) (scTCR-0547YC-S(P))
- Species Reactivity: Human
- Epitope: RQFGPDFPTI
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-4) (scTCR-0548YC-S(P))
- Epitope: RQFGPDWIVA
- MHC: HLA-A02
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-5) (scTCR-0549YC-S(P))
- Species Reactivity: Human
- Epitope: RQWGPDPAAV
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-6) (scTCR-0550YC-S(P))
- Species Reactivity: Human
- Epitope: YLGGPDFPTI
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone (1E6)-7) (scTCR-0551YC-S(P))
- Species Reactivity: Human
- Epitope: YQFGPDFPIA
- MHC: HLA-A*02:01
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Mouse Anti-INS Recombinant Soluble TCR (clone BDC12-4.1) (scTCR-0552YC-S(P))
- Epitope: VEALYLVCGEEG
- MHC: H2 class II
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Human Anti-INS Recombinant Soluble TCR (clone A15) (scTCR-0553YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone A16) (scTCR-0554YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL + OX(M1)
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone TA5) (scTCR-0555YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone TA6) (scTCR-0556YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone TC6) (scTCR-0557YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone UB6) (scTCR-0558YC-S(P))
- Species Reactivity: Human
- Epitope: RLLPLLALL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone VC4) (scTCR-0559YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone VD4) (scTCR-0560YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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Human Anti-INS Recombinant Soluble TCR (clone WB4) (scTCR-0561YC-S(P))
- Species Reactivity: Human
- Epitope: MLYQHLLPL
- MHC: HLA-A*02:01
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APC-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC981)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: APC
Compare

APC-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC984)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: APC
Compare

APC-DQB1*03:02/Human INS (LVEALYLVCGERGG) MHC Tetramer (MHC-LC1149)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: LVEALYLVCGERGG
- Conjugate: APC
Compare

PE-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0909)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: PE
Compare

APC-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0910)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: APC
Compare

FITC-DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0911)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: FITC
Compare

DRB1*04:01/Human INS (GAGSLQPLALEGSLQKRG) MHC Tetramer (MHC-CN0912)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Unconjugated
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PE-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0913)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: PE
Compare

PE-DRB1*01:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3236)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DRB1*04:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3237)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

PE-DRB1*07:01/Human INS (FVNQHLCGSHLVEAL) MHC Tetramer (MHC-LC3238)
- Class: Class II
- Antigen: INS
- Antigen Species: Human
- Peptide: FVNQHLCGSHLVEAL
- Conjugate: PE
Compare

Mouse Anti-INS Recombinant Antibody (clone 5E1) (MRO-0841-CN)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC
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DRB1*04:01/Human Proinsulin (GAGSLQPLALEGSLQKRG) MHC Monomer (MHC-YF029)
- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GAGSLQPLALEGSLQKRG
- Conjugate: Biotin
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DRB1*04:01/Human Proinsulin (GIVEQCCTSICSLYQ) MHC Monomer (MHC-YF032)
- Class: Class II
- Antigen: Proinsulin
- Antigen Species: Human
- Peptide: GIVEQCCTSICSLYQ
- Conjugate: Biotin
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Anti-INS Recombinant Antibody (Clone 5ins16) (PABS-0026)
- Derivation: Yeast cell surface display
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, FuncS
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Recombinant Human Anti-INS Soluble TCR (1C8) (ZIP-Fos/ZIP-Jun) (VS-0622-YF356)
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Mouse Anti-INS Recombinant Antibody (clone 133) (FAMAB-0184YC)
- Species Reactivity: Bovine
- Type: Mouse IgG2a
- Application: ELISA
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APC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0914)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: APC
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Mouse Anti-INS Recombinant Antibody (clone 125) (FAMAB-0185YC)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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FITC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0915)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: FITC
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Mouse Anti-INS Recombinant Antibody (clone 127) (FAMAB-0186YC)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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A*02:01/Human INS (HLVEALYLV) MHC Tetramer (MHC-CN0916)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: HLVEALYLV
- Conjugate: Unconjugated
Compare

Mouse Anti-INS Recombinant Antibody (clone 193020) (FAMAB-0187YC)
- Species Reactivity: Mouse
- Type: Mouse IgG2b, κ
- Application: ELISA, WB
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Rabbit Anti-INS Recombinant Antibody (clone 1F6) (ZG-0769J)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
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Human Anti-INS Recombinant Antibody (clone mAb49) (HPAB-1994-FY)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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Recombinant Human Anti-INS Soluble TCR (1E6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF357)
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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Recombinant Human Anti-INS Soluble TCR (clone 3F2) (scTCR-359CQ-S(P))
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
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BV421-H2-K1/Human INS (LYLVCGERV) MHC Tetramer (MHC-LC982)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERV
- Conjugate: BV421
Compare

Human Anti-INS Recombinant Antibody (clone mAb13) (HPAB-1995-FY)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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BV421-H2-K1/Human INS (LYLVCGERGF) MHC Tetramer (MHC-LC985)
- Class: Class I
- Antigen: INS
- Antigen Species: Human
- Peptide: LYLVCGERGF
- Conjugate: BV421
Compare

Recombinant Human Anti-INS Soluble TCR (3F2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF358)
- Species Reactivity: Human
- Epitope: ALWGPDPAAA
- MHC: HLA-A2
Compare

Mouse Anti-INS Recombinant Antibody (clone 193020); Fab Fragment (FAMAB-0187-YC-F(E))
- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: ELISA, WB
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Human Anti-INS Recombinant Antibody (clone mAb13); Fab Fragment (HPAB-1995-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 125); Fab Fragment (FAMAB-0185-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 127); Fab Fragment (FAMAB-0186-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 133); Fab Fragment (FAMAB-0184-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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Human Anti-INS Recombinant Antibody (clone mAb49); scFv Fragment (HPAB-1994-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-INS Recombinant Antibody (clone mAb49); Fab Fragment (HPAB-1994-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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Human Anti-INS Recombinant Antibody (clone mAb48); Fab Fragment (HPAB-1993-FY-F(E))
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 123); Fab Fragment (FAMAB-0182-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 124); Fab Fragment (FAMAB-0183-YC-F(E))
- Species Reactivity: Bovine
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 123); scFv Fragment (FAMAB-0182-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 124); scFv Fragment (FAMAB-0183-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 133); scFv Fragment (FAMAB-0184-YC-S(P))
- Species Reactivity: Bovine
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 125); scFv Fragment (FAMAB-0185-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare

Mouse Anti-INS Recombinant Antibody (clone 127); scFv Fragment (FAMAB-0186-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-INS Recombinant Antibody (clone 193020); scFv Fragment (FAMAB-0187-YC-S(P))
- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: ELISA, WB
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Human Anti-INS Recombinant Antibody (clone mAb48); scFv Fragment (HPAB-1993-FY-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Recombinant Anti-human INS VHH Single Domain Antibody (NAB-1554-VHH)
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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Mouse Anti-INS Recombinant Antibody (clone YC182); Fab Fragment (DrMAB-1026)
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Rabbit Anti-INS Recombinant Antibody (clone DS1841AB) (MOR-1841)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, WB
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Rabbit Anti-INS Recombinant Antibody (clone TH140DS) (MOR-4627)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, ICC, IHC
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Anti-INS Immunohistochemistry Kit (VS-0525-XY3566)
- Species Reactivity: Human
- Target: INS
- Application: IHC
Compare

Anti-Mouse INS Immunohistochemistry Kit (VS-0525-XY3567)
- Species Reactivity: Human, Mouse, Rat
- Target: INS
- Application: IHC
Compare

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For Research Use Only. Not For Clinical Use.

Background

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region.

Related Diseases

Maturity Onset Diabetes of the Young