APC-B*27:05/Human GCGR (RRRWHRWRL) MHC Tetramer

CAT#: MHC-LC1323

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of GCGR-derived peptide of RRRWHRWRL covering 412-420 and B*27:05 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 RNA cell line category: Cell line enhanced (HeLa, MCF7, SK-BR-3, U-87 MG)

Specifications

  • Allele
  • B*27:05
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • GCGR
  • Antigen Species
  • Human
  • Peptide
  • RRRWHRWRL
  • Range
  • 412-420
  • Conjugate
  • APC

Target

  • Antigen Introduction
  • The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
  • Alternative Names
  • GCGR; glucagon receptor; GGR; GL-R
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