Recombinant Anti-Human GCGR Antibody (Fc glycosylation)
CAT#: Gly-113LC
This product is a chimeric (mouse/human) monoclonal antibody with glycosylation site in Fc region. The Ch14.18 with enhanced ADCC specifically binds human GD2 and can be potentially used in the treatment of high-risk neuroblastoma.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71228/1338_A11_7_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HeLa, MCF7, SK-BR-3, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215644-GCGR
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Glyco-engineering
- Glycosylation site
- Fc region
- Glycoform (ratio)
- G0F, G1F, G2F
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- GD2 (Disialoganglioside)
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- Human
- Antibody Isotype
- IgG1, κ
- Clone
- Ch14.18
- Applications
- ELISA
Target
- Alternative Names
- GD2 ganglioside; GD2
- Related Disease
- High-risk neuroblastoma
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-066CQ | Anti-Human GCGR Recombinant Antibody (3C7v11) | ELISA, FC, WB | Humanized antibody |
| TAB-066CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (3C7v11) | ELISA, FC, WB | Humanized antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-065CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (H6.23v3) | ELISA, FC, WB | Human antibody |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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