Recombinant Anti-GCGR Vesicular Antibody, EV Displayed (VS-0425-YC385)
CAT#: VS-0425-YC385
The Recombinant Anti-GCGR Vesicular Antibody, EV Displayed (VS-0425-YC385) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to GCGR-expressed cells or tissues. The GCGR is a glucagon receptor crucial for controlling blood glucose levels, with defects causing non-insulin-dependent diabetes mellitus.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71228/1338_A11_7_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HeLa, MCF7, SK-BR-3, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215644-GCGR
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- GCGR
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Glucagon receptor
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Golgi apparatus
- Introduction
- The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
- Alternative Names
- GGR
- Gene ID
- 2642
- UniProt ID
- P47871
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Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-099 | Mouse Anti-GCGR Recombinant Antibody (clone mAb7) | ELISA, WB, FuncS | Mouse IgG |
| PABZ-214 | Human Anti-GCGR Recombinant Antibody (clone mAb1) | Neut, WB | Human IgG |
| HPAB-0138-FY | Human Anti-GCGR Recombinant Antibody (HPAB-0138-FY) | Block | Human IgG4, κ |
| HPAB-0817-FY | Human Anti-GCGR Recombinant Antibody (HPAB-0817-FY) | ELISA, RIA, FC | Human IgG |
| HPAB-0818-FY | Human Anti-GCGR Recombinant Antibody (HPAB-0818-FY) | ELISA, RIA, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-099 | Mouse Anti-GCGR Recombinant Antibody (clone mAb7); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| PSBZ-214 | Human Anti-GCGR Recombinant Antibody (clone mAb1); scFv Fragment | Neut, WB | Human scFv |
| HPAB-3385LY-F(E) | Human Anti-GCGR Recombinant Antibody (clone CBL150); Fab Fragment | ELISA | Human Fab |
| HPAB-3386LY-F(E) | Human Anti-GCGR Recombinant Antibody (clone CBL151); Fab Fragment | ELISA | Human Fab |
| HPAB-3387LY-F(E) | Human Anti-GCGR Recombinant Antibody (clone CBL152); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-214 | Human Anti-GCGR Recombinant Antibody (clone mAb1); Fab Fragment | Neut, WB | Human Fab |
| HPAB-0138-FY-S(P) | Human Anti-GCGR Recombinant Antibody; scFv Fragment (HPAB-0138-FY-S(P)) | Block | Human scFv |
| HPAB-1620LY-S(P) | Human Anti-GCGR Recombinant Antibody (clone CBL034); scFv Fragment | ELISA, IHC | Human scFv |
| HPAB-0105LY-S(P) | Human Anti-GCGR Recombinant Antibody; scFv Fragment (HPAB-0105LY-S(P)) | ELISA | Human scFv |
| HPAB-3045LY-S(P) | Human Anti-GCGR Recombinant Antibody; scFv Fragment (HPAB-3045LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-066CQ | Anti-Human GCGR Recombinant Antibody (3C7v11) | ELISA, FC, WB | Humanized antibody |
| TAB-066CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (3C7v11) | ELISA, FC, WB | Humanized antibody |
| TAB-066CQ-F(E) | Anti-Human GCGR Recombinant Antibody Fab Fragment (3C7v11) | ELISA, FC, WB | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-063CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (mAb5) | ELISA, FC | |
| TAB-064CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (3C7) | ELISA, FC, WB | |
| TAB-067CQ-S(P) | Mouse Anti-GCGR Recombinant Antibody; scFv Fragment (TAB-067CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-063CQ-F(E) | Anti-Human GCGR Recombinant Antibody Fab Fragment (mAb5) | ELISA, FC | |
| PABX-067-F (E) | Recombinant Mouse Anti-GR-2 Antibody Fab Fragment (F6) | WB, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-065CQ-S(P) | Anti-Human GCGR Recombinant Antibody scFv Fragment (H6.23v3) | ELISA, FC, WB | Human antibody |
| TAB-068CQ-S(P) | Human Anti-GCGR Recombinant Antibody; scFv Fragment (TAB-068CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-069CQ-S(P) | Human Anti-GCGR Recombinant Antibody; scFv Fragment (TAB-069CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-065CQ-F(E) | Anti-Human GCGR Recombinant Antibody Fab Fragment (H6.23v3) | ELISA, FC, WB | Human antibody |
| TAB-068CQ-F(E) | Human Anti-GCGR Recombinant Antibody; Fab Fragment (TAB-068CQ-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-113LC | Recombinant Anti-Human GCGR Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY112 | Human Anti-GCGR scFv-Fc Chimera (VS-0425-FY112) | Inhib | Human IgG1, scFv-Fc |
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