APC-B*27:09/Human GCGR (RRRWHRWRL) MHC Tetramer (CAT#: MHC-LC1449)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of GCGR-derived peptide of RRRWHRWRL covering 412-420 and B*27:09 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71228/1338_A11_7_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71228/1338_A11_7_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HeLa, MCF7, SK-BR-3, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215644-GCGR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215644-GCGR
Specifications
- Allele
- B*27:09
- Class
- Class I
- MHC Species
- Human
- Antigen
- GCGR
- Antigen Species
- Human
- Peptide
- RRRWHRWRL
- Range
- 412-420
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
- Alternative Names
- GCGR; glucagon receptor; GGR; GL-R
- Gene ID
- 2642
- UniProt ID
- P47871
Downloads
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