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Anti-GCGR Recombinant Antibody Products

Anti-GCGR Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs provides a comprehensive portfolio of premium anti-GCGR recombinant antibodies, meticulously developed and manufactured to the highest quality standards. Our robust platforms and stringent quality control processes ensure the reliability and efficacy of these antibodies, making them indispensable tools for researchers exploring the intricate role of GCGR in diverse biological processes.

GCGR: A Compelling Therapeutic Target for Metabolic Diseases

GCGR, a critical regulator of glucose homeostasis, plays a pivotal role in maintaining blood sugar levels by stimulating glycogen breakdown and gluconeogenesis. Excessive activation of GCGR, often linked to hyperglucagonemia, has been implicated in hyperglycemia. Given the promising results from preclinical and early clinical studies targeting GCGR, this receptor emerges as a compelling therapeutic target for the treatment of diseases associated with dysregulated glucose metabolism.

Alternative Names

Glucagon receptor; GGR; GL-R; MVAH.

Background

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
Protein class

FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (Hepatocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HeLa, MCF7, SK-BR-3, U-87 MG)

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

Anti-GCGR Recombinant Antibody Products

Creative Biolabs offers a comprehensive suite of high-quality anti-GCGR recombinant antibodies, meticulously engineered to deliver exceptional performance, specificity, and sensitivity. Our antibodies are available in various formats to accommodate a broad spectrum of research applications, such as WB, ELISA, FC, etc. Backed by our robust platforms and rigorous quality control processes, our anti-GCGR antibodies provide reliable and reproducible results, empowering researchers to delve deeper into the intricate role of GCGR in health and disease.

Table 1. Featured anti-GCGR recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
TAB-068CQ Human Anti-GCGR Recombinant Antibody (TAB-068CQ) Human, Cynomolgus monkey, Mouse, Rat Human IgG2 ELISA, FC
ZG-0142U Human Anti-GCGR Recombinant Antibody (clone 9G1) Human Humanized IgG1 ELISA
HPAB-0138-FY Human Anti-GCGR Recombinant Antibody (HPAB-0138-FY) Human Human IgG4, κ Block
HPAB-0105LY Human Anti-GCGR Recombinant Antibody (HPAB-0105LY) Human Human IgG ELISA
HPAB-1620LY Human Anti-GCGR Recombinant Antibody (clone CBL034) Human Human IgG ELISA, IHC

Creative Quality Control

Creative Biolabs adheres to rigorous quality control standards throughout the production process of anti-GCGR recombinant antibodies. Our comprehensive quality assurance procedures involve state-of-the-art analytical techniques, stringent testing protocols, and meticulous documentation to ensure the purity, specificity, potency, and lot-to-lot consistency of our products. This commitment to quality enables researchers to rely on our anti-GCGR antibodies for accurate and reproducible results in their scientific investigations.

Fig.1 ELISA analysis. (Creative Biolabs Original)Fig.1 ELISA analysis of anti-GCGR antibody
(Cat# ZG-0142U, Creative Biolabs).

Fig.2 SDS-PAGE analysis. (Creative Biolabs Original)Fig.2 SDS-PAGE analysis of anti-GCGR antibody
(Cat# TAB-068CQ, Creative Biolabs).

Fig.3 HPLC analysis. (Creative Biolabs Original)Fig.3 HPLC analysis of anti-GCGR antibody
(Cat# TAB-068CQ, Creative Biolabs).

Customer Reviews

Excellent
Bi***a
Anti-Human GCGR Recombinant Antibody (3C7v11) (TAB-066CQ)
I recently utilized Creative Biolabs' anti-GCGR recombinant antibodies for flow cytometry experiments. The antibodies exhibited exceptional specificity and sensitivity, allowing for precise identification and quantification of GCGR-expressing cells. The clear and distinct staining patterns obtained were instrumental in our research, enabling us to draw meaningful conclusions.
18/Oct/2022
Excellent
Ah***s
Mouse Anti-GCGR Recombinant Antibody (clone 40C5) (MOB-1786z)
I was impressed with Creative Biolabs' anti-GCGR recombinant antibodies in ELISA experiments. The antibodies were very sensitive, allowing for the identification of low amounts of GCGR protein. Furthermore, the great specificity reduced background noise, yielding dependable and quantifiable data. These antibodies greatly improved the precision and efficiency of our study.
21/Nov/2023
Excellent
Kr***a
Human Anti-GCGR Recombinant Antibody (clone CBL034) (HPAB-1620LY)
Creative Biolabs' anti-GCGR recombinant antibodies significantly enhanced our immunohistochemistry studies. The exceptional specificity of these antibodies enabled precise localization of GCGR protein expression within tissue sections, providing invaluable insights into its spatial distribution and cellular localization. The clear and intense staining patterns generated by these antibodies were instrumental in advancing our understanding of GCGR's role in various biological processes.
22/May/2024

Anti-GCGR Recombinant Antibody Production

Creative Biolabs employs cutting-edge genetic engineering technology to manufacture high-quality anti-GCGR recombinant antibodies on a flexible scale. Our robust platforms ensure precise design, optimization, and expression, enabling constant performance and dependability to meet customers’ various demands.

Featured Anti-GCGR Recombinant Antibody Production Platforms Fig.4 Milligram-scale. (Creative Biolabs Original)
Fig.4 Milligram-scale anti-GCGR recombinant antibody production.

Fig.5 Gram-scale. (Creative Biolabs Original)Fig.5 Gram-scale anti-GCGR recombinant antibody production.

Anti-GCGR Recombinant Antibody Modalities

Creative Biolabs provides a comprehensive suite of high-quality anti-GCGR recombinant antibodies to cater to the diverse research needs of scientists worldwide.

Fig.6 GCGR antibody production and modalities. (Creative Biolabs Original)Fig.6 Full-length anti-GCGR recombinant antibody production and modalities.

GCGR-Targeted Drug Information

Public Drug Information Targeting GCGR

Table 2. Public drug targeting GCGR.

Company Research Phase Classification Condition
Lilly
Locemia Solutions (Originator)
Launched - 2019 Glucagon
Polypeptides, from 10 AA to 40 AA
Recombinant proteins
Diabetes
Diabetes type 1
Diabetes type 2
Hypoglycemia
Bedford (Hikma)
Eisai
Hikma
Novo Nordisk (Originator)
Paladin
Launched - 1993 Glucagon
Polypeptides, from 41 AA
Recombinant proteins
Gastrointestinal Disorders
Hypoglycemia
Hanmi (Originator) Phase II Fc Fusion Proteins
Glucagon Analogues
Pegylated Drugs
Polypeptides, from 41 AA
Hyperinsulinemia
Hypoglycemia
Obesity
Ionis Pharmaceuticals (Originator)
Isis Pharmaceuticals (Ionis Pharmaceuticals)
Suzhou Ribo Life Science
Phase II Antisense Therapy
Single-stranded oligodeoxyribonucleotide (DNA)
Diabetes type 2
Amgen (Originator)
Duke University
REMD Biotherapeutics
Phase II Human Monoclonal Antibodies Diabetes type 1
Diabetes type 2
Hyperglycemia
NGM Biopharmaceuticals (Originator) Phase I Humanized Monoclonal Antibodies Diabetes
Lilly (Originator) Phase I Humanized Monoclonal Antibodies Hyperglycemia
Regeneron (Originator) Phase I Human Monoclonal Antibodies Diabetes type 2
Ionis Pharmaceuticals (Originator)
Isis Pharmaceuticals (Ionis Pharmaceuticals)
ISIS Pharma (Pfizer)
Ortho-McNeil (Janssen)
Ortho-McNeil-Janssen (Janssen)
Phase I Antisense Therapy
Oligonucleotides
Diabetes
Diabetes type 2
Peking University Third Hospital (PUTH) (Originator)
REMD Biotherapeutics (Originator)
Preclinical Human Monoclonal Antibodies Diabetes type 2

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

To delve deeper into the capabilities of Creative Biolabs' high-quality anti-GCGR recombinant antibodies, please reach out to us at your convenience. We are committed to providing comprehensive solutions and support to researchers worldwide.

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