Anti-Human BSG Recombinant Antibody scFv Fragment (2.6.1 (ABX-RB2)) (CAT#: TAB-1285CL-S(P))
This antibody specifically binding to CD147 results in the killing of T-cells, B-cells, and/or monocytes. So it can also be used in the treatment of graft versus host disease (GVHD), organ transplant rejection diseases (including, without limitation, renal transplant, ocular transplant, and others), cancers (including, without limitation, cancers of the blood (i.e., leukemias and lymphomas), pancreatic, and others), autoimmune diseases, inflammatory diseases, and others.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74870/1466_A2_3_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74870/1466_A2_3_selected.jpg
Figure 2 Testis
(Sertoli cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_4_6.jpg
(Sertoli cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_4_6.jpg
Figure 3 Heart muscle
(Cardiomyocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_6_6.jpg
(Cardiomyocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_6_6.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_7_5.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_B_7_5.jpg
Figure 5 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_3.jpg
Figure 6 Kidney
(Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_5.jpg
(Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2427/6189_A_7_5.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172270-BSG
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172270-BSG
Specifications
- Immunogen
- CEM cells
- Host Species
- Human
- Type
- Fully human antibody
- Specificity
- Human
- Clone
- 2.6.1 (ABX-RB2)
- Related Disease
- Graft versus host disease (GVHD), organ transplant rejection diseases (such as renal transplant, ocular transplant), cancers (such as cancers of the blood (i.e., leukemias and lymphomas), pancreatic), autoimmune diseases, inflammatory diseases
Target
- Alternative Names
- M6; OK; 5F7; TCSF; CD147; EMMPRIN; BSG; basigin (Ok blood group)
- Gene ID
- 682
- UniProt ID
- P35613
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B050(A) | Recombinant Anti-human BSG Intrabody [(D-Arg)9] | WB, ICC, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B050(G) | Recombinant Anti-human BSG Intrabody [+36 GFP] | IF, FC, FuncS | scFv-(+36GFP) |
| IAB-B050(T) | Recombinant Anti-human BSG Intrabody [Tat] | WB, ICC, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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