Recombinant Anti-human CD2 Intrabody [(D-Arg)₉] (CAT#: IAB-B074(A))

• Immunogen
• human CD2 molecule

• Host Species
• human

• Type
• scFv-(D-Arg)₉

• Cell Penetrating Peptide
• (D-Arg)₉
  It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.

• Species Reactivity
• human

• Applications
• Formats of immunological tests: Protein fragment complementation; Western blot; Functional studies

• Purity
• >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE

• Storage
• Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

• Alternative Names
• CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

• Gene ID
• 914

• UniProt ID
• P06729

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