Mouse Anti-CD2 (clone 35.1) scFv-Fc Chimera
CAT#: VS-0425-FY80
CD2 is a cell surface molecule involved in T-cell activation and adhesion. This scFv-Fc construct targets CD2 and is being researched for its potential use in modulating immune responses in autoimmune and inflammatory diseases.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line JURKAT
Immunofluorescent staining of human cell line JURKAT shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3883/2036_G3_1_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3883/11413_A_8_8.jpg
Normal Tissue
Figure 3 Tonsil
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3883/11413_A_4_8.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (HDLM-2, JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000116824-CD2
❮
❯
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human CD2
- Species Reactivity
- Human
- Clone
- 35.1
- Applications
- ELISA, Inhibition
- Related Disease
- Penis Squamous Cell Carcinoma and Immune Defect Due To Absence Of Thymus
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- CD2 Molecule; CD2 Antigen (P50), Sheep Red Blood Cell Receptor; T-Cell Surface Antigen T11/Leu-5; Erythrocyte Receptor; Rosette Receptor; LFA-3 Receptor; LFA-2
- Gene ID
- 914
- UniProt ID
- P06729
- Long Name
- CD2 Molecule
- Cellular Localization
- Cell membrane, Membrane
- Protein Refseq
- NP_001315538.1; NP_001758.2
- Function
- CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-FY80. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 35.1"
- CAT
- Product Name
See other products for "CD2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1136z | Mouse Anti-CD2 Recombinant Antibody (clone 23B6) | ELISA, FC, IF, IHC, IP, FuncS | Mouse IgG2b, κ |
| FAMAB-1620CQ | Mouse Anti-CD2 Recombinant Antibody (clone OX34) | Block, FC | Mouse IgG2a |
| ZG-0087J | Mouse Anti-CD2 Recombinant Antibody (clone 3F3) | IHC-P, IF | Mouse IgG |
| ZG-0088J | Mouse Anti-CD2 Recombinant Antibody (ZG-0088J) | IHC-P, IF | Mouse IgG |
| ZG-0089J | Mouse Anti-CD2 Recombinant Antibody (ZG-0089J) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B074(A) | Recombinant Anti-human CD2 Intrabody [(D-Arg)9] | PCA, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B074(G) | Recombinant Anti-human CD2 Intrabody [+36 GFP] | ELISA, IF, Neut, FuncS | scFv-(+36GFP) |
| IAB-B074(T) | Recombinant Anti-human CD2 Intrabody [Tat] | ELISA, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-104 | Anti-Human CD2 Recombinant Antibody (TAB-104) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-110CL | Anti-Human CD2 Recombinant Antibody (BTI-322) | FuncS | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-295CQ | Mouse Anti-CD2 Recombinant Antibody (clone CBL975) | WB, FC, Neut, IHC | Mouse IgG1, κ |
| NEUT-296CQ | Mouse Anti-CD2 Recombinant Antibody (clone RPA-2.10) | WB, Neut, FC, IHC, IHC-Fr | Mouse IgG1, κ |
| NEUT-297CQ | Mouse Anti-CD2 Recombinant Antibody (clone TS1/8) | Neut, FC, CyTOF | Mouse IgG1 |
| NEUT-299CQ | Rat Anti-CD2 Recombinant Antibody (clone 12-15) | Neut, FC, IP | Rat IgG1, κ |
| NEUT-300CQ | Rat Anti-CD2 Recombinant Antibody (clone RM2) | FC, FuncS, Neut | Rat IgG2b, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-298CQ | Mouse Anti-CD2 Recombinant Antibody (clone TS218) | Block, FC, IP, WB | Mouse IgG1, κ |
| NEUT-301CQ | Rat Anti-CD2 Recombinant Antibody (clone RM2-5) | FC, IP, Block, Costim | Rat IgG2b, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0542 | Hi-Affi™ Rabbit Anti-CD2 Recombinant Antibody (clone DS542AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0019-LSX-S(P) | Human Anti-CD2 Recombinant Antibody (clone 35.1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0019-LSX-F(E) | Human Anti-CD2 Recombinant Antibody (clone 35.1); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-104 | Afuco™ Anti-CD2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-104) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY48 | AbPlus™ Anti-CD2 Magnetic Beads (TS218) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY84 | Mouse Anti-NHP CD2 Recombinant Antibody (clone RPA-2.10) | IF, FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY21 | CytoStream™ Mouse Anti-CD2 Recombinant Antibody (clone RPA-2.10) | FC | Mouse IgG1, kappa |
| VS13-YC155 | CytoStream™ Rabbit Anti-CD2 Recombinant Antibody (VS13-YC155) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC276 | Recombinant Anti-CD2 Vesicular Antibody, EV Displayed (VS-0425-YC276) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1134 | Anti-CD2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1135 | Anti-Mouse CD2 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
-3.png)
Application: ELISA, FC, Block, SPR
![Figure 2 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in HPLC](https://img.creativebiolabs.net/productimages/COA-TAB-1611CL-F(E)-2.png)
Application: Depletion, FuncS
Application: WB, IHC, ELISA, FC
Application: ELISA, Inhib, FuncS
Application: WB, ELISA, FC, IHC, IF, IP
-3.jpg)
Application: IB, FC, ELISA, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
