Human Anti-CD2 Recombinant Antibody (clone 35.1)

CAT#: HPAB-0019-LSX

Recombinant monoclonal antibody to CD2. Clone 35.1 is a chimeric antibody that can be potentially used in preventing the production of the human immunodeficiency virus (HIV-1) in HIV-1-infected T cells.

Published Data Gene Expression
Figure 1 A graph showing, by fluorescence-activated cell sorting, that chimeric monoclonal antibody CD2 SFv-Ig competes effectively with murine anti-CD2 monoclonal antibody 35.1 for binding to CD2 antigen on Jurkat T cells. Figure 2 A dose-response curve for treatment of infected cells with chimeric humanized monoclonal antibody CD2 SFv-Ig, murine anti-CD2 monoclonal antibody, and CD5-Ig fusion protein antibody as a control, plotted against the inhibition of production of HIV-1 p24 antigen.
Figure 1 IF staining of human cell line JURKAT Figure 2 Lymph node Figure 3 Tonsil Figure 4 RNA cell line category: Group enriched (HDLM-2, JURKAT, MOLT-4)

Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric
  • Type
  • Chimeric IgG
  • Specificity
  • Human CD2
  • Species Reactivity
  • Human
  • Clone
  • 35.1
  • Related Disease
  • AIDS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Functional Assay.

Target

  • Alternative Names
  • CD2 Molecule; CD2 Antigen (P50), Sheep Red Blood Cell Receptor; T-Cell Surface Antigen T11/Leu-5; Erythrocyte Receptor; Rosette Receptor; LFA-3 Receptor; LFA-2; SRBC; Lymphocyte-Function Antigen-2; CD2 Antigen; T11
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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