Anti-Human CSF1R Recombinant Antibody (TAB-011ML)
CAT#: TAB-011ML
Recombinant monoclonal antibody to CSF1R. It is a human monoclonal antibody that can be potentially used in the treatment of Rheumatoid arthritis (RA), Pigmented villonodular synovitis (PVNS).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12323/201_C4_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12323/29746_B_7_6_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8970/24179_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8970/24179_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8970/24179_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8970/24179_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (BEWO, SK-BR-3)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182578-CSF1R
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- IgG4, κ
- Specificity
- Human CSF1R
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Inhibition
- Conjugate
- Unconjugated
- Related Disease
- Rheumatoid arthritis (RA), Pigmented villonodular synovitis (PVNS)
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
REVIEWS AND Q&AS
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Excellent for Flow Cytometry and IHC
We use this antibody extensively in flow cytometry and IHC. Its robust performance and consistent results help us quantify CSF1R expression accurately, aiding in detailed tissue analysis and cellular profiling.
Versatile and Reliable
The versatility of this antibody across multiple applications-from ELISA to inhibition studies-has broadened our experimental horizons, ensuring robust data collection for comprehensive molecular studies.
Q&As
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What research applications is this antibody suitable for?
A: The antibody is highly effective for Enzyme-Linked Immunosorbent Assay (ELISA), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC), and inhibition studies, allowing for versatile applications across different research domains.
-
How does this antibody contribute to research in inflammatory diseases?
A: It aids in studying diseases like rheumatoid arthritis and pigmented villonodular synovitis (PVNS) by allowing researchers to explore the role of CSF1R in these conditions, providing insights into therapeutic targets.
View the frequently asked questions answered by Creative Biolabs Support.
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Biosimilar Overview
Please refer to Cabiralizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Cabiralizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CSF1R"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1863z | Mouse Anti-CSF1R Recombinant Antibody (clone 32G11) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2b |
| HPAB-0575-CN | Human Anti-CSF1R Recombinant Antibody (HPAB-0575-CN) | ELISA, Block | Chimeric (mouse/human) IgG4, κ |
| HPAB-0963-FY | Human Anti-CSF1R Recombinant Antibody (HPAB-0963-FY) | WB, FC, ELISA | Human IgG |
| HPAB-0964-FY | Human Anti-CSF1R Recombinant Antibody (HPAB-0964-FY) | WB, FC, ELISA | Human IgG |
| HPAB-0965-FY | Human Anti-CSF1R Recombinant Antibody (HPAB-0965-FY) | WB, FC, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H23 | Anti-Human CSF1R Recombinant Antibody (TAB-H23) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-076MZ | Human Anti-CSF1R Recombinant Antibody (TAB-076MZ) | WB | Human IgG4 |
| TAB-078MZ | Human Anti-CSF1R Recombinant Antibody (TAB-078MZ) | ELISA | Humanized IgG |
| TAB-076MZ-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-076MZ-S(P)) | WB | Human scFv |
| TAB-078MZ-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-078MZ-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-178CL | Afuco™ Anti-CSF1R Recombinant Antibody (AFC-178CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
| AFC-TAB-H23 | Afuco™ Anti-CSF1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H23) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-011ML | Afuco™ Anti-CSF1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-011ML) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-077MZ | Mouse Anti-CSF1R Recombinant Antibody (TAB-077MZ) | ELISA | Mouse IgG2a, κ |
| TAB-079MZ | Anti-Mouse CSF1R Recombinant Antibody (AFS98) | FC | |
| TAB-077MZ-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (TAB-077MZ-S(P)) | ELISA | Mouse scFv |
| TAB-077MZ-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (TAB-077MZ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-508CQ | Mouse Anti-CSF1R Recombinant Antibody (clone CBL141) | Neut, WB | Mouse IgG1 |
| NEUT-509CQ | Mouse Anti-CSF1R Recombinant Antibody (clone CBL809) | WB, Neut | Mouse IgG1 |
| NEUT-510CQ | Mouse Anti-CSF1R Recombinant Antibody (clone MM0467-5V36) | WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0825 | Hi-Affi™ Rabbit Anti-CSF1R Recombinant Antibody (clone DS825AB) | ELISA | Rabbit IgG |
| MOR-4112 | Hi-Affi™ Rabbit Anti-CSF1R Recombinant Antibody (clone SI183DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0574-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0574-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0575-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0575-CN-S(P)) | ELISA, Block | Mouse scFv |
| HPAB-0576-CN-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0576-CN-S(P)) | ELISA, Block | Humanized scFv |
| HPAB-0577-CN-S(P) | Mouse Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0577-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0579-CN-S(P) | Human Anti-CSF1R Recombinant Antibody; scFv Fragment (HPAB-0579-CN-S(P)) | ELISA, FC, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0574-CN-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0574-CN-F(E)) | ELISA, Block | Mouse Fab |
| HPAB-0575-CN-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0575-CN-F(E)) | ELISA, Block | Human Fab |
| HPAB-0576-CN-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0576-CN-F(E)) | ELISA, Block | Humanized Fab |
| HPAB-0577-CN-F(E) | Mouse Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0577-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0579-CN-F(E) | Human Anti-CSF1R Recombinant Antibody; Fab Fragment (HPAB-0579-CN-F(E)) | ELISA, FC, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY97 | Human Anti-CSF1R (clone RG7155) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC551 | Recombinant Anti-CSF1R Vesicular Antibody, EV Displayed (VS-0425-YC551) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1705 | Anti-CSF1R Immunohistochemistry Kit | IHC | |
| VS-0525-XY1706 | Anti-Mouse CSF1R Immunohistochemistry Kit | IHC |
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