Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.H) (CAT#: TAB-084MZ-F(E))
This antibody is a CTLA-4-specific agonistic monoclonal antibody which may stimulate of CTLA-4 and may be used in the treatment of a disease selected from the group consisting of rheumatoid arthritis, type I diabetes, multiple sclerosis, systemic lupus erythematosus, psoriasis, ulcerative Ulerosa, Crohn's disease and so on.
Host: Human
Isotype: Humanized antibody
Applications: Enzyme-linked Immunosorbent Assay, Flow Cytometry
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- TGN2422.H
- Applications
- Enzyme-linked Immunosorbent Assay, Flow Cytometry
- Related Disease
- Rheumatoid arthritis, type I diabetes, multiple sclerosis, systemic lupus erythematosus, psoriasis, ulcerative Ulerosa, Crohn's disease and so on
Target
- Alternative Names
- CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- Gene ID
- 1493
- UniProt ID
- P16410
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
| CAT | Product Name | Application | Type |
| TAB-067 | Anti-Human CTLA4 Recombinant Antibody (Ipilimumab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-206 | Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab)) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG2 |
Immunotoxin
| CAT | Product Name | Application | Type |
| AGTO-G015E | Anti-CTLA4 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G015S | Anti-CTLA4 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G015M | Anti-CTLA4 immunotoxin (scFv)-Mel | Cytotoxicity assay, Function study |
Rat Antibody
| CAT | Product Name | Application | Type |
| TAB-195CL | Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL) | ELISA | Mouse IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
| TAB-083MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.H) | ELISA, FC | Humanized antibody |
| TAB-084MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2422.H) | ELISA, FC | Humanized antibody |
| TAB-088MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-088MZ) | ELISA | Human IgG |
| TAB-091MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-091MZ) | ELISA | Human IgG1 |
| TAB-092MZ | Human Anti-CTLA4 Recombinant Antibody (TAB-092MZ) | ELISA | Human IgG1 |
Chimeric Antibody
| CAT | Product Name | Application | Type |
| TAB-085MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ | Anti-Human CTLA4 Recombinant Antibody (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-086MZ-S(P) | Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C) | ELISA, FC | Chimeric antibody (mouse/human) |
| TAB-085MZ-F(E) | Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C) | ELISA, FC | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
| TAB-087MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-087MZ) | ELISA | Mouse IgG |
| TAB-089MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-089MZ) | ELISA | Mouse IgG1 |
| TAB-090MZ | Mouse Anti-CTLA4 Recombinant Antibody (TAB-090MZ) | ELISA | Mouse IgG1 |
| TAB-093MZ | Anti-Human CTLA4 Recombinant Antibody (Mu-26B) | ELISA | |
| TAB-087MZ-F(E) | Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-087MZ-F(E)) | ELISA | Mouse Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
| NEUT-567CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone 14D3) | FC, FuncS, Neut, IP, WB | Mouse IgG2a, κ |
| NEUT-569CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone AS32) | WB, Neut | Mouse IgG1 |
| NEUT-570CQ | Human Anti-CTLA4 Recombinant Antibody (clone YC030) | Neut | Human IgG1, κ |
| NEUT-572CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4B9) | FC, Block, ELISA, IP | Hamster IgG |
| NEUT-580CQ | Rat Anti-Ctla4 Recombinant Antibody (clone CBL855) | FC, Neut, WB | Rat IgG2 |
Blocking Antibody
| CAT | Product Name | Application | Type |
| NEUT-568CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone L3D10) | FC, Block | Mouse IgG1, κ |
| NEUT-571CQ | Mouse Anti-CTLA4 Recombinant Antibody (clone BN13) | Block, FC | Mouse IgG2a |
| NEUT-577CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone MAB0835) | Block, FC | Hamster IgG |
| NEUT-578CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone RYNmCTLA-4) | Block | Hamster IgG |
| NEUT-581CQ | Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4F10-11) | Block, FC, WB | Hamster IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
| MOR-0855 | Hi-Affi™ Rabbit Anti-CTLA4 Recombinant Antibody (clone DS855AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
| HPAB-0157-FY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0157-FY) | Activ | Humanized IgG1, κ |
| HPAB-0749LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0749LY) | FuncS, ELISA | Human IgG |
| HPAB-0750LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0750LY) | FuncS, ELISA | Human IgG |
| HPAB-0751LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0751LY) | FuncS, ELISA | Human IgG |
| HPAB-0752LY | Human Anti-CTLA4 Recombinant Antibody (HPAB-0752LY) | FuncS, ELISA | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-0157-FY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0157-FY-F(E)) | Activ | Humanized Fab |
| HPAB-N0343-YC-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-N0343-YC-F(E)) | FC, ELISA | Human Fab |
| HPAB-0749LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0749LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0750LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0750LY-F(E)) | FuncS, ELISA | Human Fab |
| HPAB-0751LY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0751LY-F(E)) | FuncS, ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
| AFC-TAB-067 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ipilimumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-206 | Afuco™ Anti-CTLA4 ADCC Recombinant Antibody (Ticilimumab (= Tremelimumab)), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-M0041-YC-S(P) | Mouse Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-M0041-YC-S(P)) | ELISA, FC, FuncS | Mouse scFv |
| HPAB-M0042-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-M0042-YC-S(P)) | ELISA, FC, FuncS | Human scFv |
| HPAB-M0043-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-M0043-YC-S(P)) | ELISA, FC, FuncS | Human scFv |
| HPAB-1100-FY-F(E) | Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-1100-FY-F(E)) | ELISA | Human Fab |
| HPAB-S0013-YC-S(P) | Human Anti-CTLA4 Recombinant Antibody (clone 6.1.1); scFv Fragment | ELISA, Block | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
| HPAB-AP860-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP860-YC) | ELISA, Block | Camel VHH |
| HPAB-AP861-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP861-YC) | ELISA, Block | Camel VHH |
| HPAB-AP862-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP862-YC) | ELISA, Block | Camel VHH |
| HPAB-AP863-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP863-YC) | ELISA, Block | Camel VHH |
| HPAB-AP864-YC | Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP864-YC) | ELISA, Block | Camel VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
* Abbreviations
AgonistAgonist
BABioassay
InhibInhibition
PGProteogenomics
StimStimulation
WBWestern Blot
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