Recombinant Dromedary Anti-FAP Single Domain Antibody (HPAB-0619-CN) (CAT#: HPAB-0619-CN)
A novel VHH antibody specifically binds to FAP with high affinity. This FAP nanometer antibody can be applied to prepare FAP detection reagent or anti-tumor drugs.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_9_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_9_3.jpg
Figure 2 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_8_4.jpg
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_8_4.jpg
Figure 3 Kidney
(Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_7_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_7_5.jpg
Figure 4 Testis
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_4_6.jpg
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_4_6.jpg
Figure 5 Smooth muscle
(Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_B_6_7.jpg
(Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_B_6_7.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, hTERT-RPE1, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078098-FAP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078098-FAP
Specifications
- Immunogen
- Synthesized FAP polypeptide
- Host Species
- Dromedary
- Derivation
- VHH phage display library
- Type
- VHH
- Specificity
- Human FAP
- Species Reactivity
- Human
- Clone
- HPAB-0619-CN
- Applications
- Used for immunoassay techniques such as: Enzyme Linked Immunoabsorbent Assay
- Related Disease
- Tumor
Product Property
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- FAP; fibroblast activation protein, alpha; FAPA; SIMP; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase;
- Gene ID
- 2191
- UniProt ID
- B4DLR2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Fap"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-211 | Anti-Human FAP Recombinant Antibody (Sibrotuzumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG1 - kappa |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022WM | Human Anti-FAP Recombinant Antibody (TAB-022WM) | FC, ELISA | Human IgG1 |
| TAB-024WM | Human Anti-FAP Recombinant Antibody (TAB-024WM) | IHC, ELISA, FC, IF | Human IgG1 |
| TAB-022WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) | FC, ELISA | Human scFv |
| TAB-024WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-024WM-S(P)) | ELISA, FC, IF | Human scFv |
| TAB-022WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) | FC, ELISA | Human Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-150LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-151LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-152LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-153LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-150LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-151LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-152LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-153LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1515MZ | Recombinant Mouse Anti-Human FAP Antibody | WB | Mouse antibody |
| MRO-1853-CN | Rabbit Anti-FAP Polyclonal Antibody (MRO-1853-CN) | WB, IF, FC | Rabbit IgG |
| HPAB-2061-FY | Human Anti-FAP Recombinant Antibody (HPAB-2061-FY) | SPR, IHC | Human IgG1 |
| HPAB-2062-FY | Human Anti-FAP Recombinant Antibody (HPAB-2062-FY) | FC | Human IgG1 |
| VS-0723-WK245 | Rabbit Anti-FAP Recombinant Antibody (VS-0723-WK245) | ELISA, FC | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) | ELISA, IF | Human scFv |
| HPAB-0171-CN-S(P) | Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0668-YJ-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0668-YJ-S(P)) | ELISA, Inhib, IHC, IF, FuncS | Human scFv |
| HPAB-2061-FY-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2061-FY-S(P)) | FC, ELISA, IF | Human scFv |
| HPAB-2062-FY-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2062-FY-S(P)) | FC, ELISA, IF | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) | ELISA, IF | Human Fab |
| HPAB-0171-CN-F(E) | Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0173-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) | ELISA | Humanized Fab |
| HPAB-0175-CN-F(E) | Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment | ELISA, WB, FC, IHC, IP | Human Fab |
| HPAB-2061-FY-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-2061-FY-F(E)) | FC, ELISA, IF | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-211 | Afuco™ Anti-FAP ADCC Recombinant Antibody (Sibrotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0661 | PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
| MHC-CN0662 | APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
| MHC-YF431 | A*02:01/Human FAP (GLFKCGIAV) MHC Pentamer | FCM | |
| MHC-YF432 | A*02:01/Human FAP alpha (ALVCYGPGI) MHC Pentamer | FCM | |
| MHC-YF573 | H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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