Anti-Human FGFR2 Recombinant Antibody (GP369/4B9) (CAT#: TAB-055WM)
Recombinant monoclonal antibody to FGFR2. Clone GP369/4B9 is a mouse monoclonal antibody which can be potentially used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or overexpression of FGFR2.
Specific Inquiry
FC
Figure 1 FGFR2 cell surface expression by flow cytometry.
The cells were incubated with 100 μL of primary FGFR2 antibodies (5 μg/mL) for 1 h, followed by incubation with 1:100 phycoerythrin (PE)-conjugated secondary antibodies (Jackson ImmunoResearch) for 30 min. Analysis of stained cells was performed on a FC500 flow cytometer (Beckman Coulter).
Bai, A., Meetze, K., Vo, N. Y., Kollipara, S., Mazsa, E. K., Winston, W. M., ... & Jiang, J. (2010). GP369, an FGFR2-IIIb–specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling. Cancer research, 70(19), 7630-7639.
Specifications
- Immunogen
- A 1: 1 mixture of human FGFR2 IgD2-IgD3 (Illb) and human FGFR2 IgD2-IgD3 (IIIc) fused with a human Fc moiety at their C-termini
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- GP369/4B9
- Applications
- FC
- Related Disease
- Cell proliferative diseases
Applications
- Application Notes
- The FGFR2 antibody has been reported in applications of Flow Cytometry.The cells were incubated with 100 μL of primary FGFR2 antibodies (5 μg/mL) for 1 h, followed by incubation with 1:100 phycoerythrin (PE)-conjugated secondary antibodies (Jackson ImmunoResearch) for 30 min.
Target
- Alternative Names
- FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14
- Gene ID
- 2263
- UniProt ID
- P21802
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1370z | Mouse Anti-FGFR2 Recombinant Antibody (clone 5F10) | ELISA, IHC, WB | Mouse IgG2b, κ |
| MOB-0737CT | Recombinant Mouse anti-Human FGFR2 Monoclonal antibody (EML2262) | ICC/IF, IHC-P, WB | |
| MRO-0579-CN | Rabbit Anti-FGFR2 Recombinant Antibody (clone JM10-60) | WB, IP | Rabbit IgG |
| MRO-0580-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone 1-F1-E7) | WB, IF, FC | Mouse IgG1 |
| MRO-0581-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone A5-E10-G7) | WB, IF, IHC | Mouse IgG1 |
Customer Reviews and Q&As
Customer Review
Q&As
-
Detailed Documentation
The antibody comes with extensive and detailed documentation, including usage protocols and validation data. Makes experimental planning and execution straightforward. -
Rapid Delivery
The product was delivered quickly and in excellent condition. Prompt services along with an outstanding product redefine the user experience. -
Robust for Multiple Assays
Very robust antibody, suitable for various research applications. We used it in cell-based assays with consistent performance across the board.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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