Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); scFv Fragment
CAT#: NS-027CN-S(P)
Anti-FGFR2 antibody can be used for antibody-based therapies for FGFR2-related diseases or conditions such as cancer. This product also can be used in the diagnostics field.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm, cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human skin
Immunohistochemical staining of human skin shows strong ctyoplasmic positivity in keratinocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10886/26036_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, CACO-2, HaCaT, HAP1, NTERA-2, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000066468-FGFR2
❮
❯
Specifications
- Immunogen
- Recombinant Human FGFR2 protein
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human scFv
- Specificity
- Human FGFR2
- Species Reactivity
- Human, Mouse
- Clone
- M048-D01
- Applications
- ELISA, WB, FC
- Related Disease
- FGFR2-related diseases or conditions such as cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Fibroblast Growth Factor Receptor 2; Keratinocyte Growth Factor Receptor; Bacteria-Expressed Kinase; EC 2.7.10.1; K-SAM; KGFR; BEK; Protein Tyrosine Kinase, Receptor Like 14; BEK Fibroblast Growth Factor Receptor; Craniofacial Dysostosis 1; Jackson-Weiss Syndrome; Pfeiffer Syndrome; Crouzon Syndrome; CD332 Antigen; EC 2.7.10; FGFR-2; BFR-1; CD332; BBDS; CEK3; ECT1; TK14; TK25; CFD1; KSAM; JWS
- Gene ID
- 2263
- UniProt ID
- P21802
REVIEWS AND Q&AS
CITATIONS
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Robust scFv Performance
We used this scFv fragment (clone M048-D01) in ELISA to detect FGFR2. The binding was strong and specific. The phage display origin of this antibody seems to ensure high affinity for the fibroblast growth factor receptor.
Versatile Application Range
This product is versatile; we successfully tested it in WB and FC. It binds well to human FGFR2, aiding our research into the signaling cascades influenced by this receptor in cancer cell lines.
Q&As
-
How is this FGFR2 antibody produced?
A: This Human Anti-FGFR2 Recombinant Antibody (clone M048-D01) is an scFv Fragment produced via Phage display library technology. It is designed to bind Human FGFR2 and also reacts with Mouse FGFR2.
-
What research areas is this antibody suitable for?
A: The antibody can be used for antibody-based therapies research for FGFR2-related diseases or conditions such as cancer, as well as in diagnostics. It is validated for ELISA, Western Blot (WB), and Flow Cytometry (FC).
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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